A5073584743- RNA modifications and cancer
- RNA and protein synthesis mechanisms
- Corneal Surgery and Treatments
- Research in Cotton Cultivation
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Spaceflight effects on biology
- Gene expression and cancer classification
- Genomics and Phylogenetic Studies
- Corneal surgery and disorders
- Trace Elements in Health
- Network Security and Intrusion Detection
- Anomaly Detection Techniques and Applications
- Heavy Metal Exposure and Toxicity
- Smart Cities and Technologies
- Bone and Joint Diseases
- Chemical Synthesis and Reactions
- Internet Traffic Analysis and Secure E-voting
- Genomics and Chromatin Dynamics
- ZnO doping and properties
- Ocular Surface and Contact Lens
- Graphene research and applications
- IoT and Edge/Fog Computing
- Supply Chain Resilience and Risk Management
- Genetics, Aging, and Longevity in Model Organisms
Northwestern Polytechnical University
2019-2024
Changzhi Medical College
2010-2024
Zhengzhou Children's Hospital
2015-2024
Zhengzhou University
2024
Anhui Medical University
2008-2023
Henan University of Engineering
2023
PLA Information Engineering University
2022
Guilin University of Electronic Technology
2020
Jiaozuo University
2020
Chinese Research Academy of Environmental Sciences
2020
Abstract Motivation With the decreased cost of RNA-Seq, an increasing number non-model organisms have been sequenced. Due to lack reference genomes, de novo transcriptome assembly is required. However, there limited systematic research evaluating quality assemblies and how influences downstream analysis. Results We used two authentic RNA-Seq datasets from Arabidopsis thaliana, produced using eight programs with a series k-mer sizes (from 25 71), including BinPacker, Bridger, IDBA-tran,...
Summary Methylation at the MdMYB1 promoter in apple sports has been reported as a regulator of anthocyanin pathway, but little is known about how locus recognized by methylation machinery to regulate accumulation. In this study, we analysed three differently coloured ‘Fuji’ apples and found that differences transcript levels , which encodes key biosynthesis, control content (and therefore colour) fruit skin. The CHH MR3 region (−1246 −780) were be negatively correlated with expression. Thus,...
Oral supplemented nutraceuticals derived from food sources are surmised to improve the human health through interaction with gastrointestinal bacteria. However, lack of fundamental quality control and authoritative consensus (e.g. formulation, route administration, dose dosage regimen) these non-medical yet bioactive compounds one main practical issues resulting in inconsistent individual responsiveness confounded clinical outcomes consuming nutraceuticals. Herein, we studied effects widely...
Background This study aimed to provide a comprehensive assessment of burden estimates and the secular trend vision loss due retinopathy prematurity (ROP) among people younger than 20 years, at global, regional national levels. Methods Data were obtained from Global Burden Disease Study 2019 database. The average annual percentage change (AAPC) was calculated quantify temporal trends in measures loss. Results In 2019, global age-standardised rates (ASRs) prevalence per 100 000 population 86.4...
Purpose: Without effective adjunctive therapy, the recurrence rate after excision of recurrent pterygia is high. In an effort to determine a way better reduce pterygia, we compared efficacy and safety amniotic membrane graft (AMG) alone AMG combined with intraoperative mitomycin C pterygia. Methods: Patients were randomly assigned receive followed by or 0.025% for 3 minutes (AMG-mitomycin C). who could be up more than 12 months entered data analysis. Conjunctival (potential) corneal (true)...
Lipopolysaccharide (LPS) has been associated with adverse developmental outcome, including embryonic resorption, fetal death and growth retardation, preterm delivery. In the present study, we showed that an ip injection LPS daily from gestational day (gd) 8 to gd 12 resulted in incidence of external malformations. The highest malformed fetuses was observed dams exposed 20 microg/kg LPS, which 34.9% per litter were externally malformed. addition, 17.4% 30 group 12.5% 10 Importantly,...
We describe and compare two machine learning approaches for cell classification based on label-free quantitative phase imaging with transport of intensity equation methods. In one approach, we design a multilevel integrated classifier including various individual models such as artificial neural network, extreme generalized logistic regression. another apply pretrained convolutional network using transfer the classification. As validation, show performances both between macrophages cultured...
The application of enzyme-inorganic hybrid nanoflowers in time-temperature indicators (TTIs) was studied for the first time. Lipase@Cu3(PO4)2 were prepared by interaction between lipase and copper ions. Compared with free lipase, activity increased 137%, storage stability also improved significantly. Based on enzymatic reaction glycerol triacetate, six TTI prototypes different concentrations lipase@Cu3(PO4)2 investigated. color TTIs changed from purple to yellow, finally green, activation...
Abstract Atherosclerosis is one of the leading causes morbidity and mortality, mainly due to immune response triggered by recruitment monocytes/macrophages in artery wall. Accumulating evidence have shown that matrix stiffness oxidized low‐density lipoproteins (ox‐LDL) play important roles atherosclerosis through modulating cellular behaviors. However, whether there a synergistic effect for ox‐LDL on macrophages behavior has not been explored yet. In this study, we developed model system...
Cultured human limbocorneal epithelial (HLE) cells secrete endostatin-related molecules that are augmented when the cultivated on denuded amniotic membrane (DAM). This study is to identify mechanisms for enhanced endostatin production by HLE AM.HLE were cultured dish, intact AM (IAM) or DAM. Collagen XVIII alpha1 mRNA was analyzed real-time quantitative PCR. In HLE/DAM cultures, inhibitors of MMPs (GM-6001; 1,10-phenanthroline), cathepsins (E64; cathepsin B inhibitor II), elastase...
Abstract Summary: The NCI-60 human tumor cell line panel is an invaluable resource for cancer researchers, providing drug sensitivity, molecular and phenotypic data a range of types. CellMiner web that provides tools the acquisition analysis quality-controlled data. supports queries up to 150 drugs or genes, but output Excel file each gene. This format makes it difficult researchers explore from large queries. Companion application facilitates exploration visualization CellMiner, further...
Network security situational assessment, the core task of network awareness, can obtain situation by comprehensively analyzing various factors that affect status. Thus, assessment provide accurate state evaluation and trend prediction for users. Although plenty methods have been proposed, there are still many problems to solve. First, because high dimensionality input data, computational complexity in model construction could be very high. Moreover, most existing schemes trade overhead...
Epidemiological studies about the effect of essential metal mixture on fasting plasma glucose (FPG) levels among elderly people are sparse. The object this study was to examine associations single metals and with FPG in Chinese community-dwelling people.The recruited 2348 total. Inductively coupled plasma-mass spectrometry adopted detect vanadium (V), selenium (Se), magnesium (Mg), cobalt (Co), calcium (Ca), molybdenum (Mo) urine. relationships between were evaluated by linear regression...
Abstract Transplantation of cultivated human limbo‐corneal epithelial (HLE) cells has been recognized as an effective stem cell (SC) therapy for treating corneal SC deficiency caused by burn or other diseases. With this technique, cryo‐preserved intact amniotic membrane (IAM) successfully used a culture substrate and carrier, is reported to preferentially preserve HLE stem/progenitor in vitro. However, little known about what factors released are involved the progenitor cell‐preserving...