A5101607071- Endometrial and Cervical Cancer Treatments
- Folate and B Vitamins Research
- Endometriosis Research and Treatment
- Ovarian cancer diagnosis and treatment
- Lung Cancer Treatments and Mutations
- Thyroid Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Iron Metabolism and Disorders
- Multiple and Secondary Primary Cancers
- Ultrasound and Cavitation Phenomena
- Privacy-Preserving Technologies in Data
- Privacy, Security, and Data Protection
- Cervical Cancer and HPV Research
- Cancer Immunotherapy and Biomarkers
- Uterine Myomas and Treatments
- Fluoride Effects and Removal
- Occupational and environmental lung diseases
- Cancer-related gene regulation
- Pancreatic and Hepatic Oncology Research
- Renal cell carcinoma treatment
- Wnt/β-catenin signaling in development and cancer
- Fluid Dynamics and Mixing
- Nuclear reactor physics and engineering
- Cancer Risks and Factors
- Autophagy in Disease and Therapy
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
University of Chinese Academy of Sciences
2023
Soochow University
2023
Shaanxi Normal University
2017-2022
The Affiliated Yongchuan Hospital of Chongqing Medical University
2020-2021
Chongqing Medical University
2020-2021
Argonne National Laboratory
2021
Xijing Hospital
2020
Wenzhou Medical University
2019
First Affiliated Hospital of Wenzhou Medical University
2019
Purpose Splenic metastases (SM) from breast cancer (SMBC) are exceedingly rare. To date, the relevant literature is primarily based on pan-tumour species, with only a few studies exploring SM specifically in relation to cancer. As such, present retrospective study explored clinicopathological characteristics and prognoses of patients SMBC at care centre authors’ hospital. Methods Data newly diagnosed metastatic (MBC) between June 2017 2022 were extracted medical records Clinicopathological...
The purpose of this study was to find a cut-off value the immunohistochemical parameter Ki67 for stage I-II endometrial cancer.The clinicopathological data 318 patients with stages cancer who received primary surgical treatment were retrospectively analyzed. A predicting recurrence determined by using receiver operating characteristic curve and Youden index. Cox regression performed screen factors associated cancer. Based on Ki67, divided into two groups, differences parameters between...
Cannabinoid receptor 2 (CB2R) has been reported to play an important role in the regulation of pathogenesis and progression myocardial infarction (MI). Here we tried investigate its potential mechanisms. The ratio infarct size heart issue was detected by TTC staining, cardiac functions were calculated according echocardiographic evaluation. Cell viability cardiomyocytes investigated Counting Kit-8 (CCK-8) lactate dehydrogenase (LDH) release assays. Western blot used detect autophagy-related...
Background After the 1998 mandatory folic acid fortification of enriched cereal-grain products in U.S., safety concerns were raised that excess consumption and high blood folate biomarkers detected adults may increase risk certain types cancer. Methods Baseline data from about 1400 participants National Health Nutrition Examination Survey (NHANES) 1999–2002, aged ≥ 57 years linked to Medicare mortality files through December 31, 2007. Using cox proportional hazards regression models, we...
Background The purpose of this study was to establish a nomogram combining classical parameters and immunohistochemical markers predict the recurrence patients with stage I-II endometrial cancer (EC). Methods 419 who received primary surgical treatment at First Affiliated Hospital Chongqing Medical University were involved in as training cohort. Univariate multivariate Cox regression analysis screening prognostic factors performed cohort develop model, which further validated 248 (validation...
Abstract Background and Objectives We aimed to explore the capacity of combined ratio biomarkers predict recurrence Stage I–III endometrial cancer (EC). Methods A total 473 patients were enrolled after screening. The cut‐off value was calculated by receiver operating characteristic curve (ROC). univariate multivariate Cox regression analysis used assess correlation between EC. differences clinicopathological parameters two groups divided based on threshold compared. Result ROC showed that...
Thyroid cancer is maintaining at a high incidence level and its carcinogenesis mainly affected by complex gene interaction. By analysis of the next-generation resequencing paired papillary thyroid (PTC) adjacent tissues, we found that Growth Associated Protein 43 (GAP43), phosphoprotein activated protein kinase C, might be novel markers associated with PTC. However, function in carcinoma has been poorly understood. We discovered GAP43 was significantly overexpressed these results were...
ABSTRACT Craniosynostosis, the premature fusion of one or more sutures between calvarial bones, is a common birth defect. Mutations in genes encoding receptors for transforming growth factor-beta (TGFβ) family signaling molecules have been associated with craniosynostosis, but how TGFβ regulated during suture development not known. In present study, we found that expression Smad2 and Smad3, intracellular mediators canonical signaling, gradually increases early postnatal rat both coronal...
Background Pancreatic cancer (PC) is widely recognized as one of the most malignant forms worldwide. Monotherapy with immune checkpoint inhibitors (ICI) has shown limited efficacy in treating this disease. There was controversy surrounding whether combining ICI chemotherapy provided superior outcomes compared to alone. Methods In study, patients diagnosed unresectable stage III/IV pancreatic were classified receiving programmed cell death protein 1 (PD-1) blockade plus gemcitabine and...
The aim of this study was to establish a nomogram predict the recurrence endometrial cancer (EC) by immunohistochemical markers and clinicopathological parameters evaluate discriminative power model.The data 473 patients with stages I-III who had received primary surgical treatment between October 2013 May 2018 were randomly split into two sets: training cohort validation at predefined ratio 7:3. Univariate multivariate Cox regression analysis screening prognostic factors performed in...
It is a challenging problem to preserve the friendly-correlations between individuals when publishing social-network data. To alleviate this problem, uncertain graph has been presented recently. The main idea of converting an original into form, where correlations associated probability. However, existing methods lack rigorous guarantees privacy and rely on assumption adversary's knowledge. In paper we first introduced general model for constructing graphs. Then, proposed algorithm under...
When users use location-based services to obtain accurate recommendation results, the provider needs a large amount of user's located information. At this time, worry about their information which be leaked abandon service, and some even upload dummy Owing problem that privacy is easy leaked, we proposed user-centered location model based on differential in paper, makes efficient recommendations while protecting users' privacy. Through controlling expected utility error autonomously, not...
Since the kidneys are highly involved in maintaining folate homeostasis, effect of folic acid fortification grain products may be affected by reduced kidney function. However, it is unclear what impact renal insufficiency on status. This study investigated associations function with levels serum and red blood cell (RBC) folate, plasma homocysteine presence unmetabolized (UMFA) U.S. adults. Data participants National Health Nutrition Examination Survey (NHANES) 1999–2002 aged 蠅 40 years were...
Folate and cancer incidence among adults in the U.S. Jing Hu, Wenyen Juan, Ph.D. Nadine R. Sahyoun, Ph.D., R.D. Folic acid fortification of grain products has significantly improved population folate status decreased Neural Tube Defects. Recently, concerns were raised that excessive folic intake may increase risk. We tested association between post‐fortification years NHANES 1999‐2002 participants aged 57 over. Cancer was obtained from Medicare files with 5‐8 follow up. Cox proportional...
Objective To investigate the application of accelerators in primary hospitals, and to explore advantages disadvantages domestic accelerators. Methods Twenty-six hospitals that used an equal number imported were enrolled study. Comparison was made by group t test. Results (1) The mean numbers patients treated every day 28.08 for 26 with 39.23 (P=0.45). (2) There no significant relationship hospital level equipment brand, patients, or treatment technology.(3) proportions need...
Objective To observe the gastric changes in adult male Sprague-Dawly (SD) rats irradiated by single large dose electron beam, providing animal experimental evidence for intraoperative radiotherapy cancer. Methods Thirty-eight SD were randomly divided into control and groups. The stomach of group subject to 6 MeV 20 Gy irridiation using patent technology Accurate Irradiation Experiment Table Small Animal Radiation. general conditions, injury body weight change observed at different...