Lieselotte Cloetens

ORCID: 0000-0001-5324-4410
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About
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Research Areas
  • Diet and metabolism studies
  • Food composition and properties
  • Nutritional Studies and Diet
  • Microbial Metabolites in Food Biotechnology
  • Digestive system and related health
  • Diet, Metabolism, and Disease
  • Nutrition and Health in Aging
  • Obesity, Physical Activity, Diet
  • Fatty Acid Research and Health
  • Probiotics and Fermented Foods
  • Adipokines, Inflammation, and Metabolic Diseases
  • Gut microbiota and health
  • Adipose Tissue and Metabolism
  • Metabolomics and Mass Spectrometry Studies
  • Phytoestrogen effects and research
  • Parasites and Host Interactions
  • Food Industry and Aquatic Biology
  • Body Composition Measurement Techniques
  • Research on Leishmaniasis Studies
  • Liver Disease Diagnosis and Treatment
  • Nutrition, Genetics, and Disease
  • Advanced MRI Techniques and Applications
  • Lipid metabolism and biosynthesis
  • Gastrointestinal motility and disorders
  • Statistical Methods in Clinical Trials

Lund University
2012-2024

International Union for Pure and Applied Biophysics
2019

University of Eastern Finland
2014

Oulu University Hospital
2014

Kuopio University Hospital
2014

KU Leuven
2008-2012

Abstract Background Different healthy food patterns may modify cardiometabolic risk. We investigated the effects of an isocaloric N ordic diet on insulin sensitivity, lipid profile, blood pressure and inflammatory markers in people with metabolic syndrome. Methods conducted a randomized dietary study lasting for 18–24 weeks individuals features syndrome (mean age 55 years, BMI 31.6 kg m −2 , 67% women). Altogether 309 were screened, 200 started intervention after 4‐week run‐in period, 96...

10.1111/joim.12044 article EN Journal of Internal Medicine 2013-03-02

The tolerance and prebiotic effect following oral intake by healthy human subjects of arabinoxylan-oligosaccharides (AXOS), produced partial enzymic hydrolysis the wheat fibre arabinoxlyan, were studied. A total twenty participated in present randomised, placebo-controlled cross-over study. They consumed 10 g AXOS or placebo per d each for 3 weeks with a 4-week wash-out period between. Before immediately after period, blood samples taken to measure haematological clinical chemistry...

10.1017/s0007114509992248 article EN British Journal Of Nutrition 2009-12-10

AbstractObjective: Arabinoxylooligosaccharides (AXOS) are non-digestible in the upper gastrointestinal tract and have been shown to exert prebiotic effects animals. The aim of this study was characterize influence AXOS with an average degree polymerization 15 arabinose substitution 0.26 (AXOS-15-0.26) on motility colonic bacterial metabolism healthy human volunteers.Methods: Twelve volunteers received five test meals, containing different amounts AXOS-15-0.26, one week intervals between each...

10.1080/07315724.2008.10719733 article EN Journal of the American College of Nutrition 2008-08-01

Oat beta-glucans (OBG) lower postprandial blood glucose by increasing gastrointestinal viscosity, delaying gastric emptying, and slowing absorption. While the European Food Safety Authority (EFSA) recommends a minimum intake of...

10.1039/d5fo00353a article EN cc-by Food & Function 2025-01-01

The aim of this investigation was to quantitatively compare the novel positron emission tomography (PET) hypoxia marker 2-(2-nitroimidazol-1-yl)-N-(3[(18)F],3,3-trifluoropropyl)acetamide ([(18)F]EF3) with reference tracer [(18)F]fluoromisonidazole ([(18)F]FMISO).[(18)F]EF3 or [(18)F]FMISO injected every 2 days into two separate groups rats bearing syngeneic rhabdomyosarcoma tumours. In vivo PET analysis done by drawing regions interest on images selected tissues. resulting activity data were...

10.1007/s00259-008-0907-x article EN cc-by-nc European Journal of Nuclear Medicine and Molecular Imaging 2008-08-08

Background and Aim Few studies have explored the possible plasma cholesterol lowering effects of rye consumption. The aim this secondary analysis in SYSDIET study was to investigate association between alkylresorcinols (AR), a biomarker for whole grain wheat intake, blood lipid concentrations population with metabolic syndrome. Furthermore, we analyzed associations AR C17∶0/C21∶0 ratio, suggested marker relative intake grain/bran rye, concentrations. Methods Participants were 30–65 years...

10.1371/journal.pone.0110827 article EN cc-by PLoS ONE 2014-10-23

Diet has a great impact on the risk of developing features metabolic syndrome (MetS), type 2 diabetes mellitus (T2DM), and cardiovascular diseases (CVD). We evaluated whether long-term healthy Nordic diet (ND) can modify expression inflammation lipid metabolism-related genes in peripheral blood mononuclear cells (PBMCs) during 2-h oral glucose tolerance test (OGTT) individuals with MetS. A multicenter randomized dietary study included subjects (n = 213) MetS, to ND group or control (CD)...

10.1186/s12263-016-0521-4 article EN cc-by Genes & Nutrition 2016-03-17

A healthy dietary pattern is associated with a lower risk of metabolic syndrome (MetS) and reduced inflammation. To explore this at the molecular level, we investigated effect Nordic diet (ND) on changes in gene expression profiles inflammatory lipid-related genes peripheral blood mononuclear cells (PBMCs) individuals MetS. We hypothesized that intake an ND compared to control (CD) would alter involved lipid metabolism. The MetS underwent 18/24-week randomized intervention compare CD....

10.3390/nu11122932 article EN Nutrients 2019-12-03

It has been suggested that intake of polar lipids may beneficially modulate various metabolic variables. The purpose this study was to evaluate the effect oat on postprandial and second meal glycemic regulation, blood lipids, gastrointestinal hormones, subjective appetite-related variables in healthy humans. In a randomized design, twenty subjects ingested four liquid cereal-based test beverages (42 g available carbohydrates) containing: i. 30 oil with low concentration (4%) (PLL), ii....

10.3390/nu13030988 article EN Nutrients 2021-03-18

To explore the effect of a healthy Nordic diet on global transcriptome profile in peripheral blood mononuclear cells (PBMCs) subjects with metabolic syndrome.Subjects syndrome undergo 18/24 week randomized intervention study comparing an isocaloric average habitual served as control (SYSDIET study). Altogether, 68 participants are included. PBMCs obtained before and after total RNA is subjected to analysis. 1302 probe sets differentially expressed between groups (p-value < 0.05). Twenty-five...

10.1002/mnfr.201801405 article EN Molecular Nutrition & Food Research 2019-04-09
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