- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Pulmonary Hypertension Research and Treatments
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Function and Risk Factors
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Acute Myocardial Infarction Research
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac Imaging and Diagnostics
- Gastric Cancer Management and Outcomes
- Central Venous Catheters and Hemodialysis
- Respiratory Support and Mechanisms
- Tracheal and airway disorders
- Cardiac Arrest and Resuscitation
- Heart Failure Treatment and Management
- Vascular anomalies and interventions
- Infectious Aortic and Vascular Conditions
- Dysphagia Assessment and Management
- Vascular Anomalies and Treatments
- Cardiovascular Issues in Pregnancy
Universität Hamburg
2019-2025
Asklepios
2025
Semmelweis University
2020-2024
Universitätsklinikum Gießen und Marburg
2009-2020
Klinikum Lüdenscheid
2014-2020
Justus-Liebig-Universität Gießen
2006-2018
Universities of Giessen and Marburg Lung Center
2013-2018
German Center for Lung Research
2016-2018
Kerckhoff Klinik
2015-2017
St. Agnes Hospital
2016
Einleitung: Bei Post-Covid können das periphere (PNS) und zentrale Nervensystem (ZNS) betroffen sein. Im PNS treten überwiegend demyelinisierende Polyneuropathien (PNP) auf. ZNS sind inflammatorische Veränderungen wie Enzephalitis Vaskulitis oder zerebrale Ischämien beschrieben. Morphologische Analysen einer Post-COVID assoziierten Erkrankung selten.
Introduction: Arrhythmias are a frequent complication of pulmonary hypertension (PH). Supraventricular tachycardias (SVT) predominantly reported and associated with clinical deterioration an increased mortality. In contrast, the prevalence relevance bradycardias is largely unclear. Therefore, aim present study was to determine in PH patients outline their relevance. Material methods: Between January 2000 June 2013, consecutive were pro- retrospectively enrolled two cohorts. Patients received...
Background: Recirculation during veno-venous extracorporeal membrane oxygenation reduces oxygen exchange and patient oxygenation. To minimize recirculation maximize delivery (DO2) the interaction of cannulation, ECMO flow cardiac output requires careful consideration. We investigated this in an observational trial. Methods: In 19 patients with acute respiratory distress syndrome ECMO, we measured ultrasound dilution technique calculated transfer (VO2), assess impact (CO), included CO...
Preoperative 5-fluorouracil-based radiochemotherapy (RCT), followed by total mesorectal excision, is accepted as standard therapy in rectal cancers (UICC stages II and III). The accurate evaluation of ypN status after RCT with valuable lymph node (LN) harvest essential for postoperative risk-adapted treatment decisions. Actual numbers assessed LNs validity vary extensively depending on the methods used.This prospective study validates acetone compression (AC), whole compartment embedding...
The diagnostic benefit of capsule endoscopy in suspected small-bowel disease is high and seems to be superior that with conventional methods scintigraphy. Because the limited clinical experience patients cardiac pacemakers other implanted electrical devices, it recommended should not used such cases. We investigated potential for interfere vitro.21 different leads were positioned a 0.9 % saline solution tank. Pin jacks placed contact solution. pacemaker impulse was recorded an inhibiting...
Background: Several studies have analyzed arrhythmias in patients with pulmonary hypertension (PH) and increased P-wave duration was identified as a risk factor for development of atrial fibrillation (AF). Methods: We retrospectively the incidence an initial diagnosis PH during long-term follow-up assessed prognostic value electrocardiography (ECG) data. Data from 167 were (Dana Point Classification: Group 1: 59 patients, 2: 28 3: 39 4: 41 patients). Clinical, 6-minute walk distance test,...
Background: Chronic thromboembolic pulmonary hypertension (CTEPH) may lead to typical electrocardiographic changes that can be reversed by balloon angioplasty (BPA). The aim of this study was investigate the significance rarely used electrocardiogram (ECG) parameters, possible differences between residual and significantly improved CTEPH role parameters in low mPAP (mean arterial pressure) ranges since threshold for definition has recently been adjusted (≥25 mmHg >20 mmHg). Material...
Background: Cephalic vein cutdown (CVC) and subclavian puncture (SVP) are the most commonly used access sites for transvenous lead placement of cardiac implantable electronic devices (CIEDs). Limited knowledge exists about long-term patency vascular lumen housing leads. Methods: Among 2703 patients who underwent CIED procedures between 2005 2013, we evaluated phlebographies 162 scheduled an elective replacement (median 6.4 years after first operation). The were divided into four stenosis...
Background: Central venous catheters (CVCs) are indispensable tools in intensive care and emergency medicine. CVC malpositions still occur frequently can cause various complications leading to increased patient mortality. A microbubbles test (MBT) be used confirm correct positioning. However, there is serious doubt regarding whether the currently applied threshold of a 2 s push-to-bubbles time (PTB time) for rapid atrial swirl sign (RASS) an MBT reliable accurate. The aim present study was...
Background:The evaluation of the QT interval in presence left bundle branch block (LBBB) is associated with challenge to discriminate native from prolongation due increase QRS duration.The newest formula evaluate LBBB suggests: modified during = measured minus 50% purpose this study therefore validate abovementioned clinical setting. Methods:Validation two separate groups patients: Patients who alternated between narrow and intermittent patients developed after transcatheter aortic valve...
Background and study aims: Capsule endoscopy is already an established diagnostic tool, the newly introduced capsule PillCam COLON now entering clinical studies. Because of very limited experience in patients with implantable cardioverter-defibrillators (ICDs), it generally recommended that should not be used these patients. Therefore, we investigated, vitro, possible interference between three different capsules (Given Imaging Olympus) ICDs.
Background and Aims . The study was a repeated evaluation of the experience capsule endoscopy (CE) in patients with cardiac pacemaker or implantable cardioverter defibrillator (ICD). Patients Methods A standardized questionnaire sent by manufactors Given Imaging Olympus to all centers Germany, Austria, Switzerland providing service. covers number examined patients, monitoring during CE, check electric implants before after occurrence arrhythmia, quality CE video, complications, indication...
Hemodynamic measurements provide important parameters for determining prognosis and therapy in patients with pulmonary arterial hypertension (PAH). Current guidelines do not incorporate the possible predictive value of individual changes hemodynamic variables during disease time course, there is no consensus about point reevaluation. We aimed to assess long‐term prognostic short‐term parameters. The study included 122 PAH from Giessen Pulmonary Hypertension Registry who underwent evaluation...
Pulmonary hypertension (PH) is frequently associated with an increase in sympathetic tone. This may adversely affect cardiac autonomic control. Knowledge about the clinical impact of dysfunction patients PH limited. We aimed to assess whether parameters heart rate variability (HRV) are related disease severity children PH.Parameters HRV [SDNN, standard deviation normal-to-normal intervals and SDANN, mean values for over 5 min] were determined from Holter electrocardiograms 17 without active...