Hironobu Sasaki

ORCID: 0000-0001-5355-6799
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About
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Research Areas
  • Advanced Mathematical Physics Problems
  • Spectral Theory in Mathematical Physics
  • Manufacturing Process and Optimization
  • Quantum Computing Algorithms and Architecture
  • Robotics and Sensor-Based Localization
  • Diabetes and associated disorders
  • Pancreatic function and diabetes
  • Robot Manipulation and Learning
  • Quantum Information and Cryptography
  • Quantum and electron transport phenomena
  • Advanced Surface Polishing Techniques
  • Diabetes Management and Research
  • Flexible and Reconfigurable Manufacturing Systems
  • Robotic Path Planning Algorithms
  • Nonlinear Waves and Solitons
  • Advanced Vision and Imaging
  • Distributed Control Multi-Agent Systems
  • advanced mathematical theories
  • Image Processing Techniques and Applications
  • Advanced Manufacturing and Logistics Optimization
  • Diabetes Treatment and Management
  • Quantum many-body systems
  • Teleoperation and Haptic Systems
  • Neural Networks and Applications
  • CCD and CMOS Imaging Sensors

Kagawa University
2024

Keio University
1993-2022

Keio University Hospital
2020-2022

Chiba University
2011-2021

Tohoku University Hospital
2005-2020

Nagoya University
2009-2015

Sapporo Medical University
2014

Tokyo University of Science
2010

Tokyo Metropolitan University
2006-2008

University of Fukui
2005-2006

The vaccine for the coronavirus disease 2019 (COVID-19) has been reported to potentially cause or worsen diabetes. A 73-year-old Japanese woman received two doses of Moderna COVID-19 vaccine. Four weeks after second vaccination, her glycemic control began deteriorate, and 8 patient was diagnosed with new-onset type 1 diabetes that strongly positive autoantibodies showed a disease-susceptible human leukocyte antigen haplotype, DRB1*04:05:01-DQB1*04:01:01. glucagon stimulation test suggested...

10.1111/jdi.13757 article EN cc-by-nc Journal of Diabetes Investigation 2022-01-28

Article abstract-We measured plasma levels of amyloid beta protein (A beta) ending at positions 40 40) and 42(43) [A 42(43)] in six carriers APP717 (Val to Ile) mutation linked familial Alzheimer9s disease (FAD) as well patients with sporadic AD (sAD) controls. The percentage the level A were significantly higher relative sAD, whereas decreased. In contrast, ratios similar regardless stage disease, compared non-AD neurologic controls nondemented control individuals. These results suggest...

10.1212/wnl.48.3.741 article EN Neurology 1997-03-01

Purpose The purpose of this paper is to propose a model assembly strategy generation and selection for human robot coordinated (HRC) cell assembly. High‐Mix, Low‐Volume production in small manufacturing industry, tends employ more flexible cells. authors innovative cells solve the problem persistent growing cost resources occasional changes programs configurations robots. first issue find out an optimal way allocate subtasks both humans Design/methodology/approach A dual Generalized...

10.1108/17563781111186761 article EN International Journal of Intelligent Computing and Cybernetics 2011-11-22

We study large time behavior of quantum walks (QWs) with self-dependent (nonlinear) coin. In particular, we show scattering and derive the reproducing formula for inverse in weak nonlinear regime. The proof is based on space-time estimate (linear) QWs such as dispersive estimates Strichartz estimate. Such argument standard Schrödinger equations discrete but it seems to be first applied QWs.

10.3934/dcds.2018159 article EN Discrete and Continuous Dynamical Systems 2018-01-01

Abstract Aims/hypothesis Type 2 diabetes is characterised by reduced beta cell mass (BCM). However, it remains uncertain whether the reduction in BCM type due to a decrease size or number of cells. Our aim was examine impact and on islet morphology humans with without diabetes. Methods Pancreas samples were obtained from 64 Japanese adults ( n = 26) 38) who underwent pancreatectomy. Using pancreatic tissues stained for insulin, we estimated based diameter. Beta product fractional area...

10.1007/s00125-021-05467-7 article EN cc-by Diabetologia 2021-05-03

Manufacturing industry tends to employ more flexible assembly cells for High-Mix, Low-Volume production. We has proposed an innovative human and robot hybrid cell within this purpose solve the problem of persistent growing cost resources now again changes in programs configurations robots, achieve a high manufacturing efficiency. One key issues is find out optimal way allocating subtasks both robot. In paper, model strategy generation selection coordinated (HRC) proposed. A Dual Generalized...

10.1109/iros.2011.6094715 article EN 2011 IEEE/RSJ International Conference on Intelligent Robots and Systems 2011-09-01

An extremely rare alga, Aegagropila linnaei, is known for its beautiful spherical filamentous aggregations called Lake Ball (Marimo). It has long been a mystery in biology as to why this species forms 3D ball-like aggregations. This alga also two-dimensional mat-like Here we show that forming an adaptive strategy increase biomass the limited environments suitable growth of alga. We estimate maximum attained by ball colonies and compare it mat colonies. As result, colony can become larger...

10.1038/srep03761 article EN cc-by Scientific Reports 2014-01-20

Abstract Aims/hypothesis Low birthweight is associated with a high risk of diabetes, but there are no reports discussing and pancreatic tissues in humans. The purpose this study was to examine the correlation between beta alpha cell mass Methods Sixty-four Japanese adults without diabetes who underwent pancreatectomy were able recall their weight history including included. Pancreatic stained for insulin glucagon, fractional area (BCA) (ACA) quantified. Islet size density replication also...

10.1007/s00125-020-05127-2 article EN cc-by Diabetologia 2020-04-01

Abstract We present some numerical results for nonlinear quantum walks (NLQWs) studied by the authors analytically (Maeda et al 2018 Discrete Contin. Dyn. Syst. 38 3687–3703; Maeda Quantum Inf. Process. 17 215). It was shown that if nonlinearity is weak, then long time behavior of NLQWs are approximated linear walks. In this paper, we observe decay range wider than in 3687–3703). addition, treat strong regime and show solitonic solutions appears. There several kinds soliton dynamics becomes...

10.1088/2399-6528/aafe2c article EN cc-by Journal of Physics Communications 2019-01-14

A robotic wiring harness assembly system, basing on vision and force/torque sensors, is developed to realize mating of electric connectors. In this cameras are firstly used detect the position pose a grasped connector, then corresponding bias calculated roughly guarantee connector can be contacted with other opposite part. After that, sensor judge contact styles assist system in applying searching inserting strategies correspondingly. The experiment results show proposed diagnose errors...

10.1109/mhs.2010.5669533 article EN International Symposium on Micro-NanoMechatronics and Human Science 2010-11-01

In electronic manufacturing systems, the design of robotic hand is important for successful accomplishment assembly task, and also human robot coworker coordinated assembly. Due to restrictions on architecture traditional hands, status parts, such as position rotation during process cannot be detected effectively. this research, an intelligent – i-Hand, equipped with multiple small sensors designed built purpose. Mating connectors by robot, experimental case in paper, studied evaluate i-Hand...

10.20965/jrm.2012.p0441 article EN cc-by-nd Journal of Robotics and Mechatronics 2012-06-20

In cell divisions, relative size of daughter cells should play fundamental roles in gametogenesis and embryogenesis. Differences gamete between the two mating types underlie sexual selection. Size is a key factor to regulate divisions during cleavage. cleavage, form (equal/unequal size) determines developmental fate each blastomere. However, strict validation rarely demonstrated. We cannot distinguish equal unequal by analysing only mean cells, because their means can be same. contrast,...

10.1038/srep13672 article EN cc-by Scientific Reports 2015-09-03

To detect and recover the errors occurred in task of mating connectors is vital robotic wiring harness systems. In our previous work, a set-membership approach for static piecewise affine (PWA) system was proposed. Although using force model, can be detected effectively during connectors, there are still some mistaken detections unrecognized faults, due to insufficient sensor information limitation model. Before task, various kinds grasping errors. Only unable this study, new hybrid...

10.1109/mhs.2009.5352078 article EN International Symposium on Micro-NanoMechatronics and Human Science 2009-11-01

10.1016/j.jde.2011.07.022 article EN publisher-specific-oa Journal of Differential Equations 2011-08-13

10.1016/0091-6749(88)90919-0 article EN Journal of Allergy and Clinical Immunology 1988-02-01

PRP19alpha and CDC5L are major components of the active spliceosome. However, their association process is still unknown. Here, we demonstrated that PRP19 alpha/14-3-3beta/CDC5L complex formation regulated by Akt during nerve growth factor (NGF)-induced neuronal differentiation PC12 cells. Analysis alpha mutants revealed phosphorylation at Thr 193 was critical for its binding with 14-3-3beta to translocate into nuclei in differentiation. Forced expression either sense or RNAs promoted...

10.1002/jnr.22455 article EN Journal of Neuroscience Research 2010-07-13

Correctly mating connectors is vital in robotic harness wiring systems. Although a static force model has been established based on and position information during mating, there are difficulties to be overcome implement process monitoring task with insufficient training samples. It difficult obtain consistent features from successful samples under different conditions using existing models, which makes it recognize whether the correctly completed by learning few In this study, simple new...

10.20965/jrm.2012.p0666 article EN cc-by-nd Journal of Robotics and Mechatronics 2012-08-20

We consider quantum walks with position dependent coin on 1D lattice $\mathbb{Z}$. The dispersive estimate $\| U^{t} P_{c} u_0\|_{l^{\infty}} \lesssim (1+|t|)^{-1/3} \|u_0\|_{l^1}$ is shown under $l^{1,1}$ perturbation for the generic case and $l^{1,2}$ exceptional case, where $U$ evolution operator of a walk $P_{c}$ projection to continuous spectrum. This an analogous result Schrödinger operators discrete operators. proof based oscillatory integrals expressed by Jost solutions.

10.2969/jmsj/85218521 article EN Journal of the Mathematical Society of Japan 2021-08-05

To evaluate the efficacy and safety of once-weekly (q.w.) extended-release exenatide after switching from twice-daily (b.i.d.) in patients with type 2 diabetes.

10.1111/jdi.13146 article EN cc-by-nc Journal of Diabetes Investigation 2019-09-13
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