A5087823974- Global Cancer Incidence and Screening
- Breast Cancer Treatment Studies
- Digital Radiography and Breast Imaging
- Colorectal Cancer Screening and Detection
- Cancer Risks and Factors
- AI in cancer detection
- BRCA gene mutations in cancer
- COVID-19 and healthcare impacts
- Cervical Cancer and HPV Research
- Economic and Financial Impacts of Cancer
- Breast Lesions and Carcinomas
- Health, Environment, Cognitive Aging
- Genetic factors in colorectal cancer
- Medical Imaging Techniques and Applications
- Healthcare innovation and challenges
- Reproductive tract infections research
- Health Systems, Economic Evaluations, Quality of Life
- Hepatitis B Virus Studies
- Radiomics and Machine Learning in Medical Imaging
- Cancer Genomics and Diagnostics
- Health Services Management and Policy
- Advanced X-ray Imaging Techniques
- Breast Implant and Reconstruction
- Advanced X-ray and CT Imaging
- Infrared Thermography in Medicine
Cancer Council NSW
2011-2024
The University of Sydney
2020-2024
The University of Melbourne
2014-2024
Cancer Council Australia
2013-2021
Royal Women's Hospital
2018
The Royal Melbourne Hospital
2018
Breastscreen Victoria
2018
Screen
2018
Peter MacCallum Cancer Centre
2018
Melbourne Health
2012
Key points• Emerging evidence suggests the COVID-19 pandemic has, to some extent, disrupted delivery and improvement of cancer screening programs, thus delayed diagnoses, resulting in potential adverse morbidity mortality • The extent effects is emerging.Rapid research into will inform urgent responses could also fast-track for optimisation Australia, with benefits during after response recovery AbstractThe coronavirus disease 2019 (COVID-19) has caused major disruptions many aspects life...
Australia introduced COVID-19 infection prevention and control measures in early 2020. To help prepare health services, the Australian Government Department of Health commissioned a modelled evaluation impact disruptions to population breast, bowel, cervical cancer screening programmes on outcomes services. We used Policy1 modelling platforms predict for potential participation, covering periods 3, 6, 9, 12 mo. estimated missed screens, clinical (cancer incidence, tumour staging), various...
The aim of this study was to optimise the experimental protocol and data analysis for in-vivo breast cancer x-ray imaging. Results are presented experiment at SYRMEP beamline Elettra Synchrotron using propagation-based phase-contrast mammographic tomography method, which incorporates not only absorption, but also phase information. In images tissue samples, a size corresponding full human breast, with radiologically acceptable doses were obtained, degree improvement image quality (from...
While Cumulus – a semi-automated method for measuring breast density is utilised extensively in research, it labour-intensive and unsuitable screening programmes that require an efficient valid measure on which to base recommendations. We develop automated (AutoDensity) compare terms of association with cancer risk outcomes. AutoDensity automatically identifies the area mammogram classifies similar way Cumulus, through fast, stand-alone Windows or Linux program. Our sample comprised 985...
Introduction:There are three government-funded population-based screening programs in Australia -the national breast cancer program (BreastScreen Australia), the National Cervical Screening Program (NCSP), and Bowel Cancer (NBCSP).Options for early detection of other cancers (e.g.hepatocellular carcinoma melanoma) under investigation.This study provides an overview health benefits, harms cost-effectiveness population-level breast, cervical colorectal screening, targeted-risk lung Lynch...
Mammography (MG) is the standard imaging in surveillance of women with a personal history breast cancer or DCIS (PHBC), supplemented ultrasound. Contrast Enhanced (CEM) has higher sensitivity than MG and US. We report performance CEM compared ± US.A retrospective study patients undergoing their first an Australian hospital setting between June 2006 October 2020. Cases where patient was recalled for assessment were identified, recording radiology, pathology treatment details. Blinded...
Abstract It is possible that the performance of mammographic screening would be improved if it targeted at women higher risk breast cancer or who are more likely to have their missed screening, through intensive alternative modalities. We conducted a case-control study within population-based Australian program (1,706 invasive cancers and 5,637 randomly selected controls). used logistic regression examine effects density, age, hormone therapy use, all known influence both sensitivity on...
There is a growing interest in delivering more personalised, risk-based breast cancer screening protocols. This requires population-level validation of practical models that can stratify women into risk groups. Few studies have evaluated the Gail model (NCI Breast Cancer Risk Assessment Tool) population setting; we validated this tool large, screened population. We used data from 40,158 aged 50–69 years (via lifepool cohort) participating Australia's BreastScreen programme. investigated...
Abstract Overdiagnosis is a harmful consequence of screening which particularly challenging to estimate. An unbiased setting measure overdiagnosis in breast cancer requires comparative data from screened and an unscreened cohort for at least 30 years. Such randomised will not become available, leaving us with observational over shorter time periods outcomes modelling. This collaborative effort the International Cancer Screening Network quantified variation estimated organised programmes...
Women with a personal history of breast cancer have an increased risk subsequent malignancy and may benefit from more sensitive surveillance than conventional mammography (MG). We previously reported outcomes for first episode using contrast-enhanced (CEM), demonstrating higher sensitivity comparable specificity to MG. now report CEM performance surveillance.
Objectives Breast cancer prognosis is better for smaller tumours. Women with high breast density are at higher risk of and have larger screen-detected interval cancers in mammographic screening programmes. We assess which continuous measures the strongest predictors tumour size detection therefore best to identify women who might benefit from more intensive or alternative strategies. Setting methods compared association between 1007 341 diagnosed an Australian programme 1994 1996, three...
There are currently no single disruptors to breast cancer screening akin the impact of human papillomavirus testing and vaccination on cervical screening. However, there is a groundswell interest review BreastScreen Australia program consider more risk-based protocols establish whether routinely inform women about their density. We propose framework for considered, evidence-based review. Population-level effectiveness ultimately measured through its mortality, this has been realised in...