A5045470234- Neurobiology of Language and Bilingualism
- Interpreting and Communication in Healthcare
- Language Development and Disorders
- Functional Brain Connectivity Studies
- Transcranial Magnetic Stimulation Studies
- Delphi Technique in Research
- Stroke Rehabilitation and Recovery
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Reading and Literacy Development
- Education Methods and Technologies
- Cell Image Analysis Techniques
- Cardiac Imaging and Diagnostics
- Linguistic Education and Pedagogy
- Electrical and Bioimpedance Tomography
- Clinical practice guidelines implementation
Universitätsmedizin Greifswald
2024
Klinik und Poliklinik für Neurologie
2024
Düsseldorf University Hospital
2021-2023
Forschungszentrum Jülich
2021-2023
Heinrich Heine University Düsseldorf
2021-2023
RWTH Aachen University
2021
Electrode positioning errors contribute to variability of transcranial direct current stimulation (tDCS) effects. We investigated the impact electrode on flow for tDCS set-ups with different focality.
Primary progressive aphasia (PPA) is a neurodegenerative disease characterised by impairment of speech and language abilities. Intensive teletherapy combined with remotely supervised, self-administered tDCS may be suited to remove barriers accessing potentially effective treatments, but there only limited evidence on the feasibility this approach. This pilot case series investigated feasibility, tolerability, preliminary efficacy novel telerehabilitation programme home-based, for people...
The human frontal operculum (FOp) is a brain region that covers parts of the ventral cortex next to insula. Functional imaging studies showed activations in this tasks related language, somatosensory, and cognitive functions. While precise cytoarchitectonic areas correlate these processes have not yet been revealed, earlier receptorarchitectonic analysis resulted detailed parcellation FOp. We complemented by study sample ten postmortem brains mapped posterior FOp serial, cell-body stained...
Human brain atlases provide spatial reference systems for data characterizing organization at different levels, coming from brains. Cytoarchitecture is a basic principle of the microstructural brain, as regional differences in arrangement and composition neuronal cells are indicators changes connectivity function. Automated scanning procedures observer-independent methods prerequisites to reliably identify cytoarchitectonic areas, achieve reproducible models segregation. Time becomes key...
Impaired phonological processing is a leading symptom of multifactorial language and learning disorders suggesting common biological basis. Here we evaluated studies dyslexia, dyscalculia, specific impairment (SLI), the logopenic variant primary progressive aphasia (lvPPA) seeking for shared risk genes in Broca's Wernicke's regions, being key within complex network. The identified "phonology-related genes" from literature were functionally characterized using Atlas-based expression mapping...
Zusammenfassung Einleitung/Hintergrund DC_TRAIN_APHASIA ist eine multizentrische, randomisiert-kontrollierte Studie, die seit November 2019 unter Federführung der Universitätsmedizin Greifswald durchgeführt wird (ClinicalTrials.gov Identifier: NCT03930121). Die Studie untersucht, ob adjuvante transkranielle Gleichstromstimulation („transcranial direct current stimulation“, tDCS) den Erfolg einer 3‑wöchigen intensiven Sprachtherapie bei chronischer Aphasie steigern kann. Material und Methode...
Speech-language therapists/pathologists (SLT/Ps) are key professionals in the management and treatment of primary progressive aphasia (PPA), however, there gaps education training within discipline, with implications for skills, confidence, clinical decision-making. This survey aimed to explore areas need amongst SLT/Ps working people living PPA (PwPPA) internationally upskill current future workforce communication disorders. One hundred eighty-six from 27 countries who work PwPPA...
Speech-language therapists/pathologists (SLT/Ps) are key professionals in the management and treatment of primary progressive aphasia (PPA), however, there gaps education training within discipline, with implications for skills, confidence, clinical decision-making. This survey aimed to explore areas need amongst SLT/Ps working people living PPA (PwPPA) internationally upskill current future workforce communication disorders. One hundred eighty-five from 27 countries who work PwPPA...
Abstract Objective Electrode positioning errors contribute to variability of transcranial direct current stimulation (tDCS) effects. We investigated the impact electrode on flow for tDCS set-ups with different focality. Methods Deviations from planned positions were determined using data acquired in an experimental study (N=240 datasets) that administered conventional and focal during magnetic resonance imaging (MRI). Comparison individualized electric field modeling empirically derived...
Abstract Background Although primary progressive aphasia (PPA) is considered a rarer form of dementia, individuals living with PPA are increasingly identified by healthcare professionals. Research investigating speech‐language assessment and intervention in has been conducted primarily monolingual speakers little known about clinical decision‐making pathologists (SLPs) working bilinguals PPA. Methods A comprehensive survey containing questions regarding clinician confidence, prioritization,...
Abstract Purpose Intensive speech-language therapy (SLT) delivered as telerehabilitation in combination with transcranial direct current stimulation (tDCS) may be an effective treatment option for people primary progressive aphasia (pwPPA). However, such combined approaches are technically challenging and feasibility pwPPA has not yet been established. We aimed to involve stakeholders the development of a novel approach combining remotely-supervised but independently self-administered...