Katarzyna Braune
A5093954249- Wheat and Barley Genetics and Pathology
- Crop Yield and Soil Fertility
- Biofuel production and bioconversion
- Plant Pathogens and Resistance
- Cassava research and cyanide
- Genetics and Plant Breeding
- Plant Disease Resistance and Genetics
- Fermentation and Sensory Analysis
- Genetic Mapping and Diversity in Plants and Animals
- Polyamine Metabolism and Applications
Carlsberg Laboratory
2024-2025
Abstract A pan-transcriptome describes the transcriptional and post-transcriptional consequences of genome diversity from multiple individuals within a species. We developed barley using 20 inbred genotypes representing domesticated by generating analyzing short- long-read RNA-sequencing datasets tissues. To overcome single reference bias in transcript quantification, we constructed genotype-specific (RTDs) integrated these into linear pan-genome framework to create pan-RTD, allowing...
Pangenomes are collections of annotated genome sequences multiple individuals a species
Pangenomes are collections of annotated genome sequences multiple individuals a species. The structural variants uncovered by these datasets major asset to genetic analysis in crop plants. Here, we report pangenome barley comprising long-read sequence assemblies 76 wild and domesticated genomes short-read data 1,315 genotypes. An expanded catalogue variation the includes structurally complex loci that have become hot spots gene copy number evolutionarily recent times. To demonstrate utility...
SUMMARY Barley produces several specialized metabolites, including five α‐, β‐, and γ‐hydroxynitrile glucosides (HNGs). In malting barley, presence of the α‐HNG epiheterodendrin gives rise to undesired formation ethyl carbamate in beverage production, especially after distilling. Metabolite‐GWAS identified QTLs underlying gene candidates possibly involved control relative absolute content HNGs, an undescribed MATE transporter. By screening 325 genetically diverse barley accessions, we...