Magnus Wohlfahrt Rasmussen
A5083243657- Wheat and Barley Genetics and Pathology
- Plant-Microbe Interactions and Immunity
- Chromosomal and Genetic Variations
- Plant Genetic and Mutation Studies
- Fermentation and Sensory Analysis
- Plant Virus Research Studies
- Plant Pathogenic Bacteria Studies
- Microbial Community Ecology and Physiology
- Genetics and Plant Breeding
- Plant Disease Resistance and Genetics
- Plant Parasitism and Resistance
- Environmental DNA in Biodiversity Studies
- DNA Repair Mechanisms
- Legume Nitrogen Fixing Symbiosis
- Plant tissue culture and regeneration
- Plant Stress Responses and Tolerance
- Isotope Analysis in Ecology
- Crop Yield and Soil Fertility
- CRISPR and Genetic Engineering
- Polyamine Metabolism and Applications
- Plant Pathogens and Resistance
- Genetic Mapping and Diversity in Plants and Animals
- Mycorrhizal Fungi and Plant Interactions
- Biochemical and biochemical processes
- Biofuel production and bioconversion
Carlsberg Laboratory
2021-2025
Carlsberg Group (Denmark)
2022
University of Copenhagen
2012-2017
Late Pliocene and Early Pleistocene epochs 3.6 to 0.8 million years ago
Plant mitogen-activated protein kinase (MAPK) cascades generally transduce extracellular stimuli into cellular responses. These include the perception of pathogen-associated molecular patterns (PAMPs) by host transmembrane pattern recognition receptors which trigger MAPK-dependent innate immune In model Arabidopsis, genetic evidence implicates a number MAPK cascade components in PAMP signaling, and responses to immunity-related phytohormones such as ethylene, jasmonate, salicylate. few...
Abstract A pan-transcriptome describes the transcriptional and post-transcriptional consequences of genome diversity from multiple individuals within a species. We developed barley using 20 inbred genotypes representing domesticated by generating analyzing short- long-read RNA-sequencing datasets tissues. To overcome single reference bias in transcript quantification, we constructed genotype-specific (RTDs) integrated these into linear pan-genome framework to create pan-RTD, allowing...
Abstract MAP kinase (MPK) cascades in Arabidopsis thaliana and other vascular plants are activated by developmental cues, abiotic stress, pathogen infection. Much less is known of MPK functions nonvascular land such as the moss Physcomitrella patens. Here, we provide evidence for a signaling pathway P. patens required immunity triggered associated molecular patterns (PAMPs). This induces rapid growth inhibition, novel fluorescence burst, cell wall depositions, accumulation defense-related...
Improved agricultural and industrial production organisms are required to meet the future global food demands minimize effects of climate change. A new resource for crop microbe improvement, designated FIND-IT (Fast Identification Nucleotide variants by droplet DigITal PCR), provides ultrafast identification isolation predetermined, targeted genetic in a screening cycle less than 10 days. Using large-scale sample pooling combination with digital PCR (ddPCR) greatly increases size...
Pangenomes are collections of annotated genome sequences multiple individuals a species
Pangenomes are collections of annotated genome sequences multiple individuals a species. The structural variants uncovered by these datasets major asset to genetic analysis in crop plants. Here, we report pangenome barley comprising long-read sequence assemblies 76 wild and domesticated genomes short-read data 1,315 genotypes. An expanded catalogue variation the includes structurally complex loci that have become hot spots gene copy number evolutionarily recent times. To demonstrate utility...
SUMMARY Barley produces several specialized metabolites, including five α‐, β‐, and γ‐hydroxynitrile glucosides (HNGs). In malting barley, presence of the α‐HNG epiheterodendrin gives rise to undesired formation ethyl carbamate in beverage production, especially after distilling. Metabolite‐GWAS identified QTLs underlying gene candidates possibly involved control relative absolute content HNGs, an undescribed MATE transporter. By screening 325 genetically diverse barley accessions, we...
In nature, genetic variation occurs in every population and results the evolution of a diversity new properties, some which promote survival species. To accelerate nature's based on diversity, plant breeders may induce additional mutations to raise number variations increasing chances obtain varieties with desired traits like improved nutritive quality, yields resilience biotic abiotic stress factors. Induced mutagenesis chemical mutagens is considered non-GM has been used barley (Hordeum...
Species of Saccharomyces genus have played an irreplaceable role in alcoholic beverage and baking industry for centuries. S. cerevisiae has also become organism choice industrial production alcohol other valuable chemicals a model shaping the rise modern genetics genomics past few decades. Today´s brewing faces challenges decreasing consumption traditional beer styles increasing consumer demand new styles, flavors aromas. The number currently used brewer's strains their genetic diversity is...
Novel crop improvement methodologies, including the exploitation of natural genetic variation, are urgently required to feed our rapidly growing human population in context global climate change. Here we describe a ‘Fast Identification Nucleotide variants by DigITal PCR’ (FIND-IT) method for rapid identification pre-targeted or rare alleles large genomic populations. Libraries 500,000 individuals can be screened and desired isolated within two weeks. FIND-IT is widely applicable mining...