Cynthia Voss

ORCID: 0000-0002-2600-9957
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About
Contact & Profiles
Research Areas
  • Wheat and Barley Genetics and Pathology
  • Cassava research and cyanide
  • Chromosomal and Genetic Variations
  • Crop Yield and Soil Fertility
  • Rice Cultivation and Yield Improvement
  • Fermentation and Sensory Analysis
  • Polyamine Metabolism and Applications
  • Plant Disease Resistance and Genetics
  • Plant tissue culture and regeneration
  • Plant Genetic and Mutation Studies
  • Genetics and Plant Breeding
  • Biofuel production and bioconversion
  • Plant Pathogens and Resistance
  • Genetic Mapping and Diversity in Plants and Animals
  • Food composition and properties

Carlsberg Laboratory
2019-2025

Abstract A pan-transcriptome describes the transcriptional and post-transcriptional consequences of genome diversity from multiple individuals within a species. We developed barley using 20 inbred genotypes representing domesticated by generating analyzing short- long-read RNA-sequencing datasets tissues. To overcome single reference bias in transcript quantification, we constructed genotype-specific (RTDs) integrated these into linear pan-genome framework to create pan-RTD, allowing...

10.1038/s41588-024-02069-y article EN cc-by Nature Genetics 2025-02-03

Improved agricultural and industrial production organisms are required to meet the future global food demands minimize effects of climate change. A new resource for crop microbe improvement, designated FIND-IT (Fast Identification Nucleotide variants by droplet DigITal PCR), provides ultrafast identification isolation predetermined, targeted genetic in a screening cycle less than 10 days. Using large-scale sample pooling combination with digital PCR (ddPCR) greatly increases size...

10.1126/sciadv.abq2266 article EN cc-by-nc Science Advances 2022-08-24

Pangenomes are collections of annotated genome sequences multiple individuals a species

10.1038/s41586-024-08187-1 article EN cc-by-nc-nd Nature 2024-11-13

Pangenomes are collections of annotated genome sequences multiple individuals a species. The structural variants uncovered by these datasets major asset to genetic analysis in crop plants. Here, we report pangenome barley comprising long-read sequence assemblies 76 wild and domesticated genomes short-read data 1,315 genotypes. An expanded catalogue variation the includes structurally complex loci that have become hot spots gene copy number evolutionarily recent times. To demonstrate utility...

10.1101/2024.02.14.580266 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2024-02-18

SUMMARY Barley produces several specialized metabolites, including five α‐, β‐, and γ‐hydroxynitrile glucosides (HNGs). In malting barley, presence of the α‐HNG epiheterodendrin gives rise to undesired formation ethyl carbamate in beverage production, especially after distilling. Metabolite‐GWAS identified QTLs underlying gene candidates possibly involved control relative absolute content HNGs, an undescribed MATE transporter. By screening 325 genetically diverse barley accessions, we...

10.1111/tpj.16768 article EN cc-by-nc The Plant Journal 2024-04-23

Abiotic environmental stresses have a negative impact on the yield and quality of crops. Understanding these is an essential enabler for mitigating breeding strategies it becomes more important as frequency extreme weather conditions increases due to climate change. This study analyses response barley (Hordeum vulgare L.) heat wave during grain filling in three distinct stages: itself, return normal temperature regime, process maturation desiccation. The properties structure starch produced...

10.1093/pcp/pcz155 article EN cc-by Plant and Cell Physiology 2019-08-05

Novel crop improvement methodologies, including the exploitation of natural genetic variation, are urgently required to feed our rapidly growing human population in context global climate change. Here we describe a ‘Fast Identification Nucleotide variants by DigITal PCR’ (FIND-IT) method for rapid identification pre-targeted or rare alleles large genomic populations. Libraries 500,000 individuals can be screened and desired isolated within two weeks. FIND-IT is widely applicable mining...

10.1101/2021.05.20.444969 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-05-21
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