A5013818140- Dental Implant Techniques and Outcomes
- Neurotransmitter Receptor Influence on Behavior
- Forensic Toxicology and Drug Analysis
- Periodontal Regeneration and Treatments
- Psychedelics and Drug Studies
- Nicotinic Acetylcholine Receptors Study
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and Biological Evaluation
- Dental materials and restorations
- Alcohol Consumption and Health Effects
- Chemical Synthesis and Analysis
- Corneal surgery and disorders
- Dental Radiography and Imaging
- Phenothiazines and Benzothiazines Synthesis and Activities
- Bone Tissue Engineering Materials
- Head and Neck Surgical Oncology
- Quinazolinone synthesis and applications
- Craniofacial Disorders and Treatments
- Synthesis and Reactivity of Heterocycles
- Innovative Microfluidic and Catalytic Techniques Innovation
- Oral and gingival health research
- Catalytic Cross-Coupling Reactions
- Glaucoma and retinal disorders
- Synthesis and Reactions of Organic Compounds
- Chemical Safety and Risk Management
Universitat Ramon Llull
2009-2025
Universitat Internacional de Catalunya
2016-2025
Institut Químic de Sarrià
2009-2020
Universidad Europea
2011-2019
Hospital Carlos Van Buren
2011
Instituto Tecnológico de Tijuana
2001
Abstract Objectives: The purpose of this animal study was to radiologically measure the influence abutment disconnection on bone resorption and compare platform‐switched vs. non‐platform‐switched implants. Methods: design included extraction all mandibular premolars in five canines . After 2 months, six implants were placed each dog. Four them ( PS ) two NPS Some or abutments connected disconnected at pre‐ordained post‐surgical intervals. Radiographs taken time implant placement every...
The emergence of new synthetic cathinones continues to be a matter public health concern. In fact, they are quickly replaced by structurally related alternatives. main goal the present study was characterize pharmacological profile, psychostimulant and rewarding properties novel (pentedrone, N-ethyl-pentedrone, α-PVP, N,N-diethyl-pentedrone α-PpVP) which only differs in their amino terminal substitution. Rat synaptosomes were used for [3H]dopamine uptake experiments. HEK293 transfected cells...
Abstract Recent studies have sparked renewed interest in the therapeutic potential of psychedelics for treating depression and other mental health conditions. Simultaneously, novel psychoactive substances (NPS) phenomenon, with a huge number NPS emerging constantly, has changed remarkably illicit drug market, being their scientific evaluation an urgent need. Thus, this study aims to elucidate impact amino-terminal modifications 5-MeO-DMT molecule on its interactions serotonin receptors...
While complete-arch digital-implant-scanning protocols have been described, their clinical outcomes when using polymethyl methacrylate (PMMA) as a provisional material remain insufficiently substantiated. This study aims to integrate digital solutions into implant dentistry and establish PMMA reliable for immediate-loaded protocols. Fifty-six patients received 432 implants 72 immediate fixed interim prostheses, all fabricated fully workflow. Patients were followed up at 3 months evaluate...
Several new synthetic cathinones, which mimic the effect of classical psychostimulants such as cocaine or MDMA, have appeared in global illicit drug market last decades. In fact, is continually evolving by constantly adding small modifications to common chemical structure cathinones. Thus, aim this study was investigate vitro and vivo structure-activity relationship (SAR) six novel cathinones currently popular recreational drugs, pentedrone, pentylone, N-ethyl-pentedrone (NEPD),...
The aim of this study was to describe the average angulation and dimensions pterygomaxillary area in atrophic maxilla facilitate orientation pterygoid implants during their placement.A retrospective radiologic made. A virtual implant, 13, 15, or 18 mm long, placed following axis bone, with a distance at least 2 maintained between artery palatine nerve implant. long implant inclined slightly toward palatal follow cortical bone. angles Frankfort horizontal were measured both sagittal frontal...
Changes in the molecular structure of synthetic cathinones has led to an increase number novel emerging drugs illicit drug market at unprecedented rate. Unfortunately, little is known about neuropsychopharmacology recently emerged halogen-substituted α-PVP derivatives. Thus, aim this study was investigate role para- and meta-halogen (F-, Cl-, Br-) substitutions on vitro, silico, vivo effects α-pyrrolidinopentiophenone (α-PVP) HEK293 cells expressing human dopamine or serotonin transporter...
To determine the visual and refractive outcome of photorefractive keratectomy (PRK) laser in situ keratomileusis (LASIK) eyes with prior posterior chamber phakic intraocular lens implantation for high myopia.We studied a series 37 consecutive 31 patients who underwent LASIK or PRK residual error following collamer (IOL) (Staar Surgical Implantable Contact Lens) into eye. Twenty-eight had nine PRK. Mean follow-up was 8.1 +/- 4.7 months after ablation (range, 3 to 18 mo).The preoperative mean...
Synthetic cathinones are β-keto amphetamine derivatives whose appearance has increased dramatically in the past decades. N-Ethyl substituted have been proven to potently inhibit dopamine (DA) uptake and induce psychostimulant rewarding effects mice. However, little is known about influence of alpha-carbon side-chain length N-ethyl on their pharmacological toxicological effects. Thus, aim this study was synthesize investigate vitro vivo five cathinones: N-ethyl-cathinone (NEC),...
An unusual Michael addition between 2-aryl-substituted acrylates and 3,3-dimethoxypropanenitrile which leads, depending on the reaction temperature (60 or −78 °C, respectively), to a 4-methoxymethylene-substituted 4-cyanobutyric ester 4-dimethoxymethyl is described. These compounds can be subsequently converted 4-unsubstituted pyrido[2,3-d]pyrimidines upon treatment with guanidine system under microwave irradiation.
Background: Early peri-implant bone loss has been associated to long-term implant-prosthetic failure. Different technical, surgical, and prosthetic techniques have introduced enhance the clinical outcome of dental implants in terms crestal preservation. The aim present cohort study was observe mean marginal level around two-part with gingivally tapered abutments one year after loading. Methods: Mean levels change were computed following radiological calibration linear measurement on...
Typically, healing or temporary abutments are connected and disconnected several times between implant placement definitive restoration delivery, soft tissue disruption occurs each time the abutment is reconnected. This histologic event supposed to cause bone resorption around after second-stage surgery. To minimize this clinical scenario, immediately placing never removing a day of insertion (one-stage protocol) at surgery in cases submerged implants (two-stage was suggested. paper details...
Abstract Background and Purpose New psychoactive substances such as N ‐ethylpentylone (NEP) are continuously emerging in the illicit drug market, knowledge of their effects risks, which may vary between sexes, is scarce. Our present study compares some key NEP male female mice. Experimental Approach Psychostimulant, rewarding reinforcing were investigated by tracking locomotor activity, conditioned place preference (CPP) paradigm through a self‐administration (SA) procedure, respectively,...
The objectives of this study were to record the prevalence and degree absence maxillary midline interdental papilla proportion patients displaying during maximum smile among a Caucasian population. Papillary recession was found in 46.4% participants (n = 211), while visible 38.4%, which statistically significantly less than that diagnosed intraorally with loss papillary height (P < .001). Correlations between age level lip line as well identified for individuals over 65 years age. high...
N-ethyl-pentedrone (NEPD, 2-(ethylamino)-1-phenyl-1-pentanone) is one of the latest synthetic cathinone derivatives that emerged into illicit drug market. This has psychostimulant properties and been related with several intoxications even fatalities. However, information about consequences its acute repeated consumption lacking. Thus, aim our study was to investigate behavioral effects after both NEPD exposure as well neurochemical changes. Male OF1 mice were treated an dose (1, 3 or 10...
Inverted papilloma (IP) is a benign tumour involving the paranasal sinuses. Given its tendency to recurrence and potential for malignancy, complete removal of remains treatment choice. Since 1994, we have routinely employed an extended endoscopic approach resection inverted papillomas. We present our methods outcomes.The study was conducted in academic tertiary care hospital-based practice. It retrospective review patients treated by single surgeon. IP diagnosed biopsy before surgery. With...
Two new protocols for the dehydrogenation of 5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-ones to pyrido[2,3-d]pyrimidin-7(8H)--ones are described.The first one uses NaH in DMSO an affords corresponding pyridopyrimidines when aryl substituent is present at C6.The second a more general use, allowing and alkyl substituted 5,6-dihydropyridopyrimdines upon treatment with Na 2 SeO 3 DMSO.