A5068442243- Spondyloarthritis Studies and Treatments
- Psoriasis: Treatment and Pathogenesis
- Wireless Body Area Networks
- Autoimmune and Inflammatory Disorders Research
- Bayesian Modeling and Causal Inference
- Voice and Speech Disorders
- Parkinson's Disease Mechanisms and Treatments
- Rheumatoid Arthritis Research and Therapies
- Mental Health Research Topics
- Statistical Methods and Inference
Sage Bionetworks
2021-2024
Psoriatic disease remains underdiagnosed and undertreated. We developed validated a suite of novel, sensor-based smartphone assessments (Psorcast app) that can be self-administered to measure cutaneous musculoskeletal signs symptoms psoriatic disease. Participants with psoriasis (PsO) or arthritis (PsA) healthy controls were recruited between June 5, 2019, November 10, 2021, at 2 academic medical centers. Concordance accuracy digital measures image-based machine learning models compared...
Abstract Background Psoriasis and psoriatic arthritis are common immune-mediated inflammatory conditions that primarily affect the skin, joints entheses can lead to significant disability worsening quality of life. Although early recognition treatment prevent development permanent damage, disease remains underdiagnosed undertreated due in part disparity between prevalence relative lack access clinical specialists dermatology rheumatology. Remote patient self-assessment aided by smartphone...
Ideally, a patient’s response to medication can be monitored by measuring changes in performance of some activity. In observational studies, however, any detected association between treatment (“on-medication” vs “off-medication”) and the outcome (performance activity) might due confounders. particular, causal inferences at personalized level are especially vulnerable confounding effects that arise cyclic fashion. For quick acting medications, confounded circadian rhythms daily routines....