A5075444567- Diabetes and associated disorders
- Autopsy Techniques and Outcomes
- Diet and metabolism studies
- Inflammatory Biomarkers in Disease Prognosis
- Biomedical Research and Pathophysiology
- Forensic Entomology and Diptera Studies
- Gastric Cancer Management and Outcomes
- Neurological and metabolic disorders
- Chronic Kidney Disease and Diabetes
- Electrocatalysts for Energy Conversion
- MicroRNA in disease regulation
- Natural product bioactivities and synthesis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer, Lipids, and Metabolism
- Cancer-related molecular mechanisms research
- Advanced Glycation End Products research
- Angiogenesis and VEGF in Cancer
- Brain Metastases and Treatment
- Thermal Regulation in Medicine
- Traditional Chinese Medicine Analysis
- Catalytic Processes in Materials Science
- Birth, Development, and Health
- Advanced Radiotherapy Techniques
- Neuroscience of respiration and sleep
- Curcumin's Biomedical Applications
Xuzhou Central Hospital
2013-2025
Nanjing University of Chinese Medicine
2020-2024
Shandong University of Science and Technology
2024
State Ethnic Affairs Commission
2022-2023
Southwest Minzu University
2022-2023
Wuhan Sports University
2023
Northeast Agricultural University
2014-2022
Xuzhou Cancer Hospital
2020
Jiangsu University
2020
Xuzhou Medical College
2020
VEGF/VEGFR2 pathway is the central therapeutic target in anti-angiogenic treatment multiple cancers. However, little work has been carried out concerning pro-malignancy functions of VEGFR2 that are independent its pro-angiogenesis effects gastric cancer. Here, we demonstrated up-regulation cancer tissues was a prognostic marker for poor disease-free survival and overall patients.Immunohistochemistry used to detect VTN expressions specimens. Kaplan-Meier curves were constructed analysis....
BACKGROUND: Gastric cancer is the fourth most frequent and second cause of cancer-related deaths worldwide. China has a high incidence gastric cancer. Inflammation critical component tumor progression. It been widely accepted that an inflammation-driven In this study, we investigated application value systemic inflammatory response (SIR) markers, platelet to lymphocyte ratio (PLR) neutrophil (NLR), in early diagnosis prognostic prediction patients with resectable MATERIALS AND METHODS: One...
In this multicenter, single-arm phase 2 trial (ChiCTR1900024428), patients with locally advanced gastric/gastroesophageal junction cancers receive one cycle of sintilimab (anti-PD1) and chemotherapy (S-1 nab-paclitaxel), followed by 5 weeks concurrent chemoradiotherapy sintilimab, another thereafter. Surgery is preferably scheduled within to three weeks, cycles adjuvant are administrated. The primary endpoint the pathological complete response. Our results meet pre-specified endpoint....
The aim of the study was to investigate application value neutrophil lymphocyte ratio (NLR) and platelet (PLR) in prediction chemotherapy response prognosis patients with advanced gastric cancer. In total, 120 unresectable cancer were included separated into two groups according median values NLR or PLR (NLR low: <4.62 high: ≥4.62 <235 ≥235, respectively). Low baseline level correlated improved clinicopathological characteristics, including smaller tumor size, well differentiation less...
An autoregressive distributed lag (ARDL) bounds approach and vector error correction model (VECM) are used here to better understand the role of financial development in energy demand China. Based on data from 1980 2014, ARDL yields empirical evidence that confirms existence long-run relationships among per capita, gross domestic product urbanization, economic structure, development. The VECM framework shows direction Granger causality combines short run long between variables. results...
// Yuan Gao 1, * , Wen-Jie Wang Qiaoming Zhi 2, Meng Shen 1 Min Jiang Xiaojie Bian Fei-Ran Gong 3 Chong Zhou 4 Lian 5 Meng-Yao Wu Jun Feng Tao 6 and Wei Li 6, 7 Department of Oncology, The First Affiliated Hospital Soochow University, Suzhou, China 2 General Surgery, Hematology, Radiation Xuzhou Central Hospital, Xuzhou, Suzhou Xiangcheng People's PREMED Key Laboratory for Precision Medicine, Center Systems Biology, These authors have contributed equally to this work Correspondence to: Li,...
Gastric cancer is the fourth most frequent and second cause of cancer-related mortalities worldwide. Platelets play an important multifaceted role in progression. Elevated mean platelet volume (MPV) detected peripheral blood has been identified various types cancer. In present study, we investigated application value MPV early diagnostic prognostic prediction patients with resectable gastric total, 168 were included separated into healthy control groups according to median pre-operatic (MPV...
Purpose To investigate the gut microbiome of lung cancer patients with brain metastases undergoing radiotherapy, identify key microorganisms associated radiotherapy response, and evaluate their potential as biomarkers. Methods materials This study enrolled 55 newly diagnosed metastases. Fecal samples were collected before analyzed by 16S rRNA sequencing to assess microbiome’s composition function. Patients categorized into response (n=28) non-response (n=27) groups based on treatment...
The aim of the present research was to examine toxic influence different doses zearalenone (ZEN) on liver, especially oxidative stress induced by ZEN liver. A total 48 pregnant Sprague-Dawley rats were randomly assigned into 4 treatments groups with 12 animals in each. fed a normal diet treated 0 mg/kg (control), 50 (treatment 1), 100 2), or 150 3) feed gestation days (GDs) 0–7 and then all GDs 8–20. experimental period lasted 21 days. results showed that exposure increase aspartate amino...
Gastric cancer is the fourth most frequent and second cause of cancer-related mortalities worldwide. Platelets play an important multifaceted role in progression. Elevated mean platelet volume (MPV) detected peripheral blood has been identified various types cancer. In present study, we investigated application value MPV prediction chemotherapy response prognosis patients with unresectable gastric A total 128 were included divided according to median values baseline (low MPV: <11.65 or high...
The reasonable design of atomically dispersed Ni-Nx sites in porous carbon nanostructures is an efficient strategy to enhance the electrochemical CO2 reduction reaction (CO2RR) catalytic activity. In this work, on hierarchically catalysts (HP-Ni-NC) were fabricated by a facile NaCl template-assisted pyrolysis method. exhibit large specific surface area and hierarchical structure, facilitating exposure numerous active mass/electron transport during CO2RR. Consequently, CO Faradaic efficiency...
Abstract A hydrolysis precipitation method was developed to prepare Cu based catalyst for methanol steam reforming. comparison of the and conventional coprecipitation conducted. The test results present that Cu‐ZnO@Al 2 O 3 prepared by exhibits better catalytic activity stability in MSR reaction. XRD, XRF, EDS, SEM, TPR, XPS N adsorption/desorption reveal high performance from could be attributed pore organization, surface enrichment active components higher reducibility.
Abstract: Subnuclear renal tubular epithelial cell vacuolization is a marker for diabetic ketoacidosis. Whether it because of hyperglycemia or ketoacidosis unclear. To examine the effect on cells in isolation, five cases lethal alcoholic without were examined (vitreous humor β‐hydroxybutyrate: 6.42–8.75 mM, mean 7.66 mM; and glucose: 0.1–4.2 1.46 mM). Microscopic examination kidneys revealed basal vacuoles three (60%). Seven control with acute alcohol toxicity (blood alcohol: 0.18–0.43%,...
Abstract: Basal vacuolization of renal tubular epithelial cells (so‐called Armanni–Ebstein phenomenon) has been attributed to hyperglycemia causing accumulation cytoplasmic glycogen. Review 34 autopsy cases with significant (vitreous glucose ≥15 mmol/L/270 mg/dL) was undertaken determine whether there any association between the degree and severity this morphological change (graded as 0, 1+, 2+, 3+). No demonstrated. subgroup 14 terminal without ketoacidosis then assess effect in isolation...
Angiogenesis is a critical step of breast cancer metastasis. Oncogenic Ras promotes the remodeling microenviroment. Tumor-associated macrophages (TAMs) are prominent inflammatory cell population emerging in microenviroment and facilitating angiogenesis In present study, we tried to investigate relationship between expression infiltration TAM, both which could further promote angiogenesis. Expressions Ras, CD68 CD34 were assessed by immunohistochemistry. The was evaluated counting number...
Abstract To investigate the spectrum of diseases seen in diabetes mellitus a forensic context, all autopsy reports diabetic individuals who presented to Forensic Science, South Australia ( FSSA ), over 5‐year period from 2005 2009 were studied. The leading cause death was cardiovascular disease (55.0%), followed by unnatural deaths (15.4%) and infections (9.4%). In type 1 diabetics, principal causes included (44.7%), acute metabolic complications (18.7%), (17.9%), (8.9%). However,...