- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Advanced Neuroimaging Techniques and Applications
- Medical Imaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Bone Tumor Diagnosis and Treatments
- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Glioma Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Meningioma and schwannoma management
- Bone and Joint Diseases
- Nuclear Physics and Applications
- Medical Imaging and Analysis
- Sarcoma Diagnosis and Treatment
- Advanced NMR Techniques and Applications
- COVID-19 diagnosis using AI
- Ultrasound in Clinical Applications
- Oral and Maxillofacial Pathology
- Gastric Cancer Management and Outcomes
- Particle accelerators and beam dynamics
- Pituitary Gland Disorders and Treatments
- Ocular Oncology and Treatments
- Advanced X-ray and CT Imaging
- Surgical Simulation and Training
Siemens Healthcare (Germany)
2024
Politecnico di Milano
2018-2023
German Cancer Research Center
2019
Heidelberg University
2019
National Center for Tumor Diseases
2019
KTH Royal Institute of Technology
2018
Commonwealth Scientific and Industrial Research Organisation
2016
Australian e-Health Research Centre
2016
Skull-base chordoma (SBC) can be treated with carbon ion radiotherapy (CIRT) to improve local control (LC). The study aimed explore the role of multi-parametric radiomic, dosiomic and clinical features as prognostic factors for LC in SBC patients undergoing CIRT. Before CIRT, 57 underwent MR CT imaging, from which tumour contours dose maps were obtained. MRI CT-based selected fed two survival models, singularly or by combining them factors. Adverse was given in-field recurrence progression....
Chest radiographs (CXRs) are still of crucial importance in primary diagnostics, but their interpretation poses difficulties at times.
MRI-treatment units enable 2D cine-MRI centred in the tumour for motion detection radiotherapy, but they lack 3D information due to spatio-temporal limits. To derive time-resolved information, different approaches have been proposed literature, a rigorous comparison among these strategies has not yet performed. The goal of this study is quantitatively investigate five published that volumetric MRI MRI-guided radiotherapy: Propagation, out-of-plane compensation, Fayad model, ROI-based model...
Abstract Background Quantitative imaging such as Diffusion‐Weighted MRI (DW‐MRI) can be exploited to non‐invasively derive patient‐specific tumor microstructure information for characterization and local recurrence risk prediction in radiotherapy. Purpose To characterize according proliferative capacity predict through microstructural markers derived from pre‐treatment conventional DW‐MRI, skull‐base chordoma (SBC) patients treated with proton (PT) carbon ion (CIRT) Methods Forty‐eight...
Abstract Purpose To define an optimal set of b ‐values for accurate derivation diffusion MRI parameters in the brain with segmented Intravoxel Incoherent Motion (IVIM) model. Methods Simulations signals were performed to targeting different perfusion regimes, by relying on optimization procedure which minimizes total relative error estimated IVIM computed a fitting procedure. Then, was acquired vivo healthy subjects and skull base chordoma patients compare optimized protocol clinical one....
To develop and validate an artificial intelligence algorithm for the positioning assessment of tracheal tubes (TTs) central venous catheters (CVCs) in supine chest radiographs (SCXRs) by using approach allowing adjustable definitions intended device positioning.
Purpose Proton therapy could benefit from noninvasively gaining tumor microstructure information, at both planning and monitoring stages. The anatomical location of brain tumors, such as meningiomas, often hinders the recovery information histopathology, conventional noninvasive imaging biomarkers, like apparent diffusion coefficient (ADC) diffusion‐weighted MRI (DW‐MRI), are nonspecific. aim this study was to retrieve discriminative microstructural markers ADC for meningiomas treated with...
To investigate the static magnetic field generated by a proton pencil beam as candidate for range verification means of Monte Carlo simulations, thereby improving upon existing analytical calculations. We focus on impact statistical current fluctuations and secondary protons electrons.We considered pulsed (10 μ${\umu}$ s pulse duration) during duty cycle with peak 0.2 μ$\umu$ A an initial energy 100 MeV. ran Geant4-DNA simulations in water extracted independent particle phase spaces....
________________________________________________________________________________dominant focal lesion between MR, where it is visible, and CT, not visible.Here we present preliminary technical results from a new combined registrationsegmentation framework for mapping of the dominant cancer foci defined on MR onto radiotherapy planning CT images in prostate cancer.The approach has potential to be used adaptive radiotherapy.Material Methods: Diagnostic acquired General Electric Genesis Signa...