A5013873807- Cervical Cancer and HPV Research
- Hepatitis B Virus Studies
- Genital Health and Disease
- Global Maternal and Child Health
- Reproductive tract infections research
- Innovations in Medical Education
- Colorectal and Anal Carcinomas
- Syphilis Diagnosis and Treatment
- Healthcare Policy and Management
- Hepatitis C virus research
- Primary Care and Health Outcomes
- Global Cancer Incidence and Screening
- Hepatitis Viruses Studies and Epidemiology
- Problem and Project Based Learning
- Vaccine Coverage and Hesitancy
- Healthcare Systems and Practices
- Viral-associated cancers and disorders
- Molecular Biology Techniques and Applications
- Cancer-related gene regulation
- Epigenetics and DNA Methylation
- Medication Adherence and Compliance
- Healthcare Operations and Scheduling Optimization
- Infectious Diseases and Mycology
- Global Health and Surgery
- Veterinary Practice and Education Studies
London School of Hygiene & Tropical Medicine
2015-2025
Royal College of Surgeons in Ireland
2024
Princess Margaret Cancer Centre
2023
University Health Network
2023
University of London
2012-2023
University College Cork
2023
National Cancer Institute
2021-2022
National Institutes of Health
2022
Institut d'Investigació Biomédica de Bellvitge
2019-2021
Division of Cancer Epidemiology and Genetics
2021
Abstract In 2020, the World Health Organization (WHO) launched a strategy to eliminate cervical cancer as public health problem. To support strategy, WHO published updated screening guidelines in 2021. inform this update, we used an established modeling platform, Policy1-Cervix , evaluate impact of seven primary scenarios across 78 low- and lower-middle-income countries (LMICs) for general population women. Assuming 70% coverage, found that human papillomavirus (HPV) approaches were most...
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Abstract There is limited access to effective cervical cancer screening programs in many resource‐limited settings, resulting continued high burden. Human papillomavirus (HPV) testing increasingly recognized be the preferable primary approach if affordable due superior long‐term reassurance when negative and adaptability self‐sampling. Visual inspection with acetic acid (VIA) an inexpensive but subjective inaccurate method widely used either for or triage of HPV‐positive individuals. A deep...
Background Cervical cancer screening strategies using visual inspection or cytology may have suboptimal diagnostic accuracy for detection of precancer in women living with HIV (WLHIV). The optimal screen and screen–triage strategy, age to initiate, frequency WLHIV remain unclear. This study evaluated the sensitivity, specificity, positive predictive value different cervical Africa. Methods findings aged 25–50 years attending treatment centres Burkina Faso (BF) South Africa (SA) from 5...
The COVID-19 pandemic has profoundly altered the ways in which health care professionals engage with continuing professional development (CPD), but extent to these changes are permanent remains unknown at present. This mixed-methods research aims capture perspectives of on their preferences for CPD formats, including conditions that inform in-person and online events optimum length type events.A survey was used gain a high-level perspective professionals' engagement CPD, areas interest,...
Educational research highlights active approaches to learning are more effective in knowledge retention and problem-solving. It has long been acknowledged that adapting ways of form part the challenge for new university students as pedagogical distance between didactical approach largely followed by secondary school systems world over differs quite significantly from often student-led, critical taken universities. University encounter various challenges, particularly during transition...
Squamous cervical cancers generally arise as a result of persistent infection with high-risk human papillomaviruses (hrHPV) and occur near to the squamocolumnar junction (SCJ) within transformation zone (TZ). The susceptibility TZ HPV-related carcinogenesis appears linked epithelial cell plasticity, squamous metaplasia originating from specialized stem population at this site. Two alternative populations have been implicated: keratin (K)7+ve cuboidal cells located SCJ, versus more broadly...
<ns3:p>Female genital schistosomiasis (FGS) and male (MGS) are gender-specific manifestations of urogenital schistosomiasis. Morbidity is a consequence prolonged inflammation in the human tract caused by entrapped eggs waterborne parasite, <ns3:italic>Schistosoma (S.) haematobium.</ns3:italic> Both diseases affect sexual reproductive health (SRH) millions people globally, especially sub-Sahara Africa (SSA). Awareness knowledge these largely absent among affected communities healthcare...
Abstract To support a strategy to eliminate cervical cancer as public health problem, the World Health Organisation (WHO) reviewed its guidelines for screening and treatment of pre-cancerous lesions in 2021. Women living with HIV have 6-times risk compared women general population, we harnessed model platform (‘Policy1-Cervix-HIV’) evaluate benefits harms range strategies Tanzania, country endemic HIV. Assuming 70% coverage, found that 3-yearly primary HPV without triage would reduce...
Introduction Multiplathogen home-based self-sampling offers an opportunity to increase access screening and treatment in endemic settings with high coinfection prevalence of sexually transmitted (HIV, Trichomonas vaginalis (Tv), human papillomavirus (HPV)) non-sexually pathogens ( Schistosoma haematobium (Sh )). Chronic coinfections may lead disability (female genital schistosomiasis) death (cervical cancer). The Zipime-Weka-Schista (Do self-testing sister!) study aims evaluate the validity,...
Female genital schistosomiasis (FGS) and male (MGS) are gender-specific manifestations of urogenital schistosomiasis. Morbidity is a consequence prolonged inflammation in the human tract caused by entrapped eggs waterborne parasite,
ABSTRACT Introduction Multiplathogen home-based self-sampling offers an opportunity to increase access screening and treatment. Infections include sexually transmitted (HIV, Trichomonas vaginalis (Tv), human papillomavirus [HPV] for cervical precancer detection) non-sexually pathogens ( Schistosoma haematobium (Sh)) pathogens, in endemic settings with high co-infection prevalence. Chronic infection may lead disability (female genital schistosomiasis (FGS) death (cervical cancer). The...
Background: Medications play an essential role in the management of patients who have experienced a stroke. Despite recognised importance and widespread availability secondary prevention guidelines, Irish research has shown continuous failure to meet targets upon discharge. While complex interventions involving healthcare professionals (HCPs) such as Speech Language Therapists (SLT), Occupational (OTs) Pharmacists been effective combatting medication non-adherence, community...
The World Health Organization (WHO) recommends a 2-dose HPV vaccine schedule for girls aged 9–14 years. As randomised controlled trials assessing the immunogenicity and efficacy of 1-dose are ongoing, we interviewed immunisation programme managers advisors in low middle-income countries (LMIC) about hypothetical, future reduction schedule. We conducted semi-structured interviews with LMIC national technical advisory group members (key informants; KIs) 2017, recruited their...