A5018651121- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Gynecological conditions and treatments
- Pregnancy-related medical research
- Reproductive System and Pregnancy
- Pregnancy and preeclampsia studies
- Ovarian function and disorders
- Sexual function and dysfunction studies
- Menstrual Health and Disorders
- Pelvic floor disorders treatments
- Reproductive Health and Technologies
- Ectopic Pregnancy Diagnosis and Management
- Toxic Organic Pollutants Impact
- Intestinal and Peritoneal Adhesions
- COVID-19 Impact on Reproduction
- Reproductive tract infections research
- Urinary Tract Infections Management
- Air Quality and Health Impacts
- Pregnancy and Medication Impact
- Effects and risks of endocrine disrupting chemicals
- Maternal and fetal healthcare
- Per- and polyfluoroalkyl substances research
- Fetal and Pediatric Neurological Disorders
Sapienza University of Rome
2016-2025
Policlinico Umberto I
2016-2025
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2022
Vita-Salute San Raffaele University
2022
Istituti di Ricovero e Cura a Carattere Scientifico
2022
Università degli Studi di Enna Kore
2016
University of Trieste
2016
National University Health System
2016
University of Milano-Bicocca
2016
Health City Institute
2005
The aim of this preliminary study was to determine whether psychiatric disorders, psychopathological symptoms, and alexithymia are associated with endometriosis in an Italian population.A comprising 37 patients surgically confirmed 43 controls, without clinical ultrasound signs endometriosis, carried out. Both controls were evaluated for the presence/absence alexithymia, pain symptoms (nonmenstrual pelvic pain, dysmenorrhea, dyspareunia).Statistically significant differences found between...
Endometriosis is a common gynecologic disease characterized by the ectopic growth of endometrial tissue. In industrialized countries, it affects approximately 10% women reproductive age. Its etiology unclear, but multifactorial origin considered to be most plausible. Environmental organochlorinated persistent pollutants, in particular dioxins and polychlorinated biphenyls (PCBs), have been hypothesized play role etiopathogenesis. However, results studies carried out on humans are...
Aim of this prospective, case–control study was to evaluate uterine arteries' blood flow before and after laparoscopic surgery in patients with ovarian endometriosis its possible correlation infertility. We prospectively enrolled 110 women reproductive age; 69 endometriomas scheduled for surgery, 41 controls. At enrolment, a detailed medical, gynecologic obstetric history collected. Fertility pregnancy desire were assessed. All underwent complete physical examination. Transvaginal ultrasound...
The aim of this study was to characterize the placental transfer some environmental pollutants, and explore possibility quantitatively predicting in utero exposure these contaminants from concentrations assessed maternal blood. Levels toxic substances such as pesticides (p,p’-DDE, β-HCH, HCB), polychlorinated biphenyls (PCBs), perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA) were determined serum samples 38 pregnant women living Rome cord blood their respective newborns....
A network of endometriosis experts from 16 Italian academic departments and teaching hospitals distributed all over the country made a critical appraisal available evidence definition 10 suggestions regarding measures to be de-implemented. Strong were only when high-quality was available. The aim select low-value medical interventions, characterized by an unfavorable balance between potential benefits, harms, costs, which should discouraged in women with endometriosis. following agreed...
Urged by the unmet medical needs in endometriosis treatment, often with undesirable side effects, and encouraged N-acetylcysteine (NAC) efficacy an animal model of virtual absence toxicity this natural compound, we performed observational cohort study on ovarian endometriosis. NAC treatment or no was offered to 92 consecutive Italian women referred our university hospital ultrasound confirmed diagnosis scheduled undergo laparoscopy 3 months later. According patients acceptance refusal,...
Is the combined excisional/ablative technique for treatment of ovarian endometriomas better than traditional stripping in terms recurrence rate? There is no evidence that technique, as similar rates were observed two techniques. The associated with results compared ablative, non-excisional techniques endometriomas. Excisional techniques, such stripping, have, however, been reduced reserve evaluated anti-Mullerian hormone, and surgical preserve are needed. A prospective, multicentre,...
Endometriosis is frequently associated with high levels of CA125. This marker therefore not useful for discriminating ovarian endometrioma from malignancy. The aim this study was to establish a panel complementary biomarkers that could be helpful in the differential diagnosis between endometriosis or other benign masses and cancer.Blood samples 50 healthy women, 17 patients tumors, 57 39 cancer were analyzed serum values measured following biomarkers: CA125, HE4 CA72-4.Serum CA125...
The immune system seems to be involved in the pathogenesis of endometriosis. Peritoneal chronic inflammation is present and natural killer cells macrophages abnormalities have been reported women with disease. Moreover, a higher production serum autoantibodies has found, which could related various factors; some still need clarified. correlation between endometriosis autoimmune diseases unclear few conflicting available data. aim this study was evaluate prevalence diseases, as conditions...
Alimentary nickel (Ni) may result in allergic contact mucositis (ACM), whose prevalence is >30% and present with IBS-like extra-intestinal symptoms. These symptoms are also frequent endometriosis, Ni dermatitis has already been observed endometriosis. Therefore, intestinal endometriosis depend on a ACM, low-Ni diet could improve We studied the of ACM focused effects gastrointestinal, extra-intestinal, gynecological recruited 84 women symptomatic for gastrointestinal disorders. Thirty-one...
Women with endometriosis often suffer from genito-pelvic pain. The objective of the present study was to analyze relationship between cognitive and psycho-emotional factors sexual functioning women endometriosis, comparing without endometriosis. A total 87 (EG) 100 (CG) completed a socio-demographic questionnaire; short-form McGill Pain Questionnaire (SF-MPQ); Female Sexual Functioning Index (FSFI); Distress Scale (SDS); Symptoms Checklist (SCL-90-R); Toronto Alexithymia (TAS-20); Positive...
The aim of the study was to assess length diagnostic delay symptomatic endometriosis in Italy and analyse presence correlations between socio-demographic status patients clinical characteristics/type diagnosis.This multicenter cross-sectional questionnaire-based conducted 10 tertiary Italian referral centres for diagnosis treatment endometriosis. A total 689 respondents with histologically proven onset disease pain symptoms completed an on-line self-reported questionnaire written their own...
Endometriosis is a chronic, estrogen-dependent, inflammatory disease, whose pivotal symptoms are dysmenorrhea, dyspareunia, and chronic pelvic pain (CPP). Besides the usual medical treatments, recent evidence suggests there potential benefits of oral N-acetylcysteine (NAC) on endometriotic lesions pain. The primary objective this prospective single-cohort study was to confirm effectiveness NAC in reducing endometriosis-related size ovarian endometriomas. secondary assess if may play role...