A5038252292- Machine Learning in Healthcare
- Sepsis Diagnosis and Treatment
- Telomeres, Telomerase, and Senescence
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Frailty in Older Adults
- Air Quality and Health Impacts
- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Palliative Care and End-of-Life Issues
- Cancer Cells and Metastasis
- Restraint-Related Deaths
- Cardiovascular and Diving-Related Complications
- Enhanced Recovery After Surgery
- Voice and Speech Disorders
- Neurogenetic and Muscular Disorders Research
- Microtubule and mitosis dynamics
- Liver Disease Diagnosis and Treatment
- Muscle Physiology and Disorders
- Chronic Disease Management Strategies
- Leprosy Research and Treatment
- Energy and Environment Impacts
- Metastasis and carcinoma case studies
- Liver Disease and Transplantation
- Facial Nerve Paralysis Treatment and Research
- Sleep and Work-Related Fatigue
Kangwon National University Hospital
2017-2025
Kangwon National University
2019-2024
Catholic University of Korea
2023
ORCID
2019
Cincinnati Children's Hospital Medical Center
2017
Worldwide, sepsis is the leading cause of death in hospitals. If mortality rates patients with can be predicted early, medical resources allocated efficiently. We constructed machine learning (ML) models to predict a hospital emergency department.
Background: Appropriate hospital-to-home transitional care has been recognized for its positive impact on health usage and outcomes in patients with COPD. However, there is limited research assessing effects patient-centered outcomes, focusing patient symptoms experiences. Methods: This single-blind randomized controlled trial included subjects diagnosed COPD at one of 2 university hospitals South Korea. The study 179 (transitional group [transitional care], 87; usual [usual 92). received...
: Studies have reported associations between long-term exposure to ambient air pollution and lung cancer. However, there been inconsistent reports of such with cancer by histological type. Thus, the aim this study was assess association particulate matter an aerodynamic diameter up 10 μm (PM10) nitrogen dioxide (NO2) incidence subtype in South Korea. This population-based cohort included 6,567,909 cancer-free subjects from Korean National Health Insurance Service (NHIS) database for...
Appropriate hospital-to-home transitional care has been recognized for its positive impact on health usage and outcomes in patients with COPD. However, there is limited research assessing effects patient-centered outcomes, focusing patient symptoms experiences.
Background/Aims: Sepsis-3 criteria and quick Sequential Organ Failure Assessment (qSOFA) have been advocated to be used in defining sepsis the general population. We aimed compare Chronic Liver Failure-SOFA (CLIF-SOFA) scores as predictors of in-hospital mortality cirrhotic patients admitted emergency department (ED) for infections.Methods: A total 1,622 cirrhosis at ED infections were assessed retrospectively. analyzed their demographic, laboratory, microbiological data upon diagnosis...
Background The development of lung cancer results from the interaction between genetic mutations and dynamic epigenetic alterations, although exact mechanisms are not completely understood. Changes in DNA methylation may be a promising biomarker for early detection prognosis cancer. We evaluated serial changes genome-wide patterns blood samples patients. Methods Blood were obtained three consecutive years patients (2 before, 1 year after detection) control subjects (without cancer). used...
Pressure ulcers (PUs) are a prevalent skin disease affecting patients with impaired mobility and in high-risk groups. These increase patients’ suffering, medical expenses, burden on staff. This study introduces clinical decision support system verifies it for predicting real-time PU occurrences within the intensive care unit (ICU) by using MIMIC-IV in-house ICU data. We develop various machine learning (ML) deep (DL) models real time validate Kangwon National University Hospital (KNUH)...
Background Chronic obstructive pulmonary disease (COPD) is a common chronic respiratory with increased prevalence in the elderly. Telomeres are repetitive DNA sequences found at end of chromosome, which progressively shorten as cells divide. Telomere length known to be molecular marker aging. This study aimed assess relationship between telomere and risk COPD, lung function, symptoms, emphysema index Obstructive Pulmonary Disease Dusty Areas (CODA) cohort. Methods We extracted from...
e15031 Background: Stage IV lung cancer is the most advanced state accompanied by metastasized to area around lungs or distant major organs. The common type of non-small cell cancer, which more aggressive and may spread quickly due organ-specific complex networks such as lymph blood vessels. Thus, only precise diagnostic strategy approaches will determine effectiveness actual successful clinical treatment. Until a recent date, Immunohistochemistry (IHC) for programmed death-ligand 1(PD-L1)...
<b>Background:</b> Anemia is a well-known comorbidity of COPD. Previous studies regarding hemoglobin and polycythemia have been investigated to be associated with increased mortality. In this study , we aimed retrospectively investigate the risk mortality serum hemoglobin(Hb) concentration level in COPD patients. <b>Methods:</b> A retrospective cohort study was designed using the Korean National Health Insurance Service (NHIS) -National Sample Cohort...
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TPS 682: Long-term health effects of air pollutants 2, Exhibition Hall, Ground floor, August 27, 2019, 3:00 PM - 4:30 Background: Studies have reported the associations between long-term exposure to ambient pollution and lung cancer. However, there been inconsistent reports for cancer by histological type. We aimed assess association particulate matter less than or equal 10 μm in a diameter (PM10) nitrogen dioxide (NO2) incidence subtype South Korea. Methods: This population-based...
<b>Background:</b> The Korean National Health and Nutrition Examination Survey in 2015 found that COPD prevalence was higher rural areas than urban areas. However, few studies were conducted Korea. Therefore, the purpose of this study is to investigate characteristics patients with a history employment agriculture. <b>Methods:</b> Data obtained from dusty (CODA) cohort analyzed. All participants evaluated spirometry. Questionnaires including occupational history, biomass exposure,...
<b>Purpose:</b> Sepsis is a leading cause of death in hospitals. If mortality rates septic patients can be predicted early, medical resources efficiently allocated. In this study, machine learning models were used to predict the hospital emergency department. Method: This study analyzed prospectively collected data from an ongoing multicenter cohort with sepsis identified During September 2019 and December 2020, total 7,113 analyzed. A model was developed 5,144 survivors 1,969 deaths. 130...
Abstract Gefitinib for EGFR mutated non-small cell lung cancer (NSCLC) is showing acquired resistance after 8-11 months, and about 60% of its mechanisms have been reported due to T790M mutation. In a third NSCLC, AXL expression can be observed at baseline status. And because could mechanism drug resistance, we decided monitor before treatment in NSCLC patients through circulating tumor cells (CTCs). Herein, Thirty-seven out 55 participants who showed EGFR-TKI were selected this prospective...
Although patients with chronic obstructive pulmonary disease (COPD) experience high morbidity and mortality worldwide, few biomarkers are available for COPD. Here, we analyzed potential the diagnosis of COPD by using word embedding.To determine which likely to be associated COPD, selected respiratory disease-related biomarkers. Degrees similarity between 26 were measured embedding. And infer through embedding model trained in large-capacity medical corpus, search among them. We used...