A5100703626- Helicobacter pylori-related gastroenterology studies
- Galectins and Cancer Biology
- Veterinary medicine and infectious diseases
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Brucella: diagnosis, epidemiology, treatment
- Bacteriophages and microbial interactions
- Oral microbiology and periodontitis research
- Amoebic Infections and Treatments
- Circular RNAs in diseases
- Dental Health and Care Utilization
- Toxin Mechanisms and Immunotoxins
- Gastric Cancer Management and Outcomes
- Dental Radiography and Imaging
- Genomics, phytochemicals, and oxidative stress
- Burkholderia infections and melioidosis
- Clostridium difficile and Clostridium perfringens research
- HIV, Drug Use, Sexual Risk
- Spine and Intervertebral Disc Pathology
- Salivary Gland Disorders and Functions
- Heme Oxygenase-1 and Carbon Monoxide
- Fire effects on ecosystems
- Animal Diversity and Health Studies
- MicroRNA in disease regulation
- Endodontics and Root Canal Treatments
Sichuan University
2024
West China Hospital of Sichuan University
2024
Changzhi Medical College
2023
Xinjiang Medical University
2019-2023
Shenzhen Polytechnic
2023
First Affiliated Hospital of Xinjiang Medical University
2019-2023
Army Medical University
2008-2017
Xinjiang Entry-Exit Inspection and Quarantine Bureau
2012-2015
Cytotoxin-associated-gene A (CagA) of Helicobacter pylori (H. pylori) is a virulence factor that plays critical roles in H. pylori-induced gastric inflammation. In the present study, biopsies were used for genotyping cagA and vacA genes, determining autophagic activity, severity inflammation response. It was revealed autophagy mucosal tissues infected with cagA-positive strains lower than levels produced by cagA-negative strains, accompanied accumulation SQSTM1 decreased LAMP1 expression....
Background Gastric cancer is one of the most common malignant diseases worldwide. Emerging evidence has shown that microRNAs (miRNAs) are associated with tumor development and progression. Our previous studies have revealed H. pylori infection was able to induce altered expression miR-30b in gastric epithelial cells. However, little known about potential role cancer. Methods We analyzed cell lines human tissues. examined effect mimics on apoptosis cells vitro by flow cytometry (FCM)...
The aim of this study was to prepare a novel nanoemulsion loaded with poorly water-soluble chlorhexidine acetate (CNE) improve its solubility, and specifically enhance the antimicrobial activity against Streptococcus mutans in vitro vivo. In study, CNE an average size 63.13 nm zeta potential -67.13 mV comprising 0.5% CNE, 19.2% Tween 80, 4.8% propylene glycol, 6% isopropyl myristate prepared by phase inversion method. Important characteristics such as content, size, potential, pH value did...
The crystal structure of a heme oxygenase (HO) HugZ from Helicobacter pylori complexed with has been solved and refined at 1.8 Å resolution. is part the iron acquisition mechanism H. pylori, major pathogen human gastroenteric diseases. It required for adaptive colonization in hosts. Here, we report that distinct all other characterized HOs. exists as dimer solution crystals, adopts split-barrel fold often found FMN-binding proteins but not observed hemoproteins. located intermonomer...
Abstract Brucellosis is one of the major public health problems in China, and human brucellosis represents a serious concern Xinjiang requires prediction analysis to help making early planning putting forward science preventive control countermeasures. According characteristics time series monthly reported cases from January 2008 June 2020, we used seasonal autoregressive integrated moving average (SARIMA) method nonlinear regression neural network (NARNN) method, which are widely prevalent...
BACKGROUND: Retromolar canal (RMC) arises from the mandibular (MC) behind second or third molar and travels anterosuperiorly to a retromolar foramen (RMF). RMCs RMFs have generally been ignored in anatomical textbooks rarely reviewed studied dental literature until last decades. OBJECTIVE: This study aimed characterize RMF Chinese population concerning its incidence, origin, classification via periapical radiography. METHODS: 123 dry adult mandibles were collected observe incidence of RMFs....
Skin/muscle incision and retraction (SMIR) during surgeries can lead to chronic postsurgical pain (CPSP). The underlying mechanisms are still unclear. In the present study, we showed that SMIR of thigh induced phosphorylation extracellular signal-regulated kinase (ERK), followed by serum- glucocorticoid-inducible kinase-1 (SGK1) activation in spinal dorsal horn. Intrathecal injection PD98059, an ERK inhibitor, or GSK650394, a SGK1 significantly attenuated mechanical hypersensitivity rats....
Hantaviruses are important zoonotic pathogens, and they pose a profound risk to public health. So far, there has been no evidence showing that Tula virus (TULV), one species of hantavirus, is endemic in China. In this study, we captured rodents found the had infected voles Yili region, Xinjiang, China.Rodents were by flooding their burrows mountain pasture areas Narati, Xinyuan County, Hantavirus L gene fragments amplified nest RT-PCR using genus-specific primers. Positive samples further...
This study examined the efficacy and pharmacological mechanism of pronase-assisted low-dose antibiotics for eradication Helicobacter pylori. Mongolian gerbils infected with H. pylori received 7-day treatment (omeprazole, different concentrations pronase, amoxicillin, clarithromycin), was assessed using rate colonization In orally administered thickness gastric mucous layer (GML) immunohistochemical alcian blue staining, amoxicillin in tissue serum were detected high-performance liquid...