A5103133158- Chemical Synthesis and Characterization
- Radioactive element chemistry and processing
- Covalent Organic Framework Applications
- Extraction and Separation Processes
- Adsorption and biosorption for pollutant removal
- Muscle Physiology and Disorders
- Adipose Tissue and Metabolism
- RNA Research and Splicing
- Analytical chemistry methods development
- Gut microbiota and health
- Spondyloarthritis Studies and Treatments
- Muscle metabolism and nutrition
- Metal-Organic Frameworks: Synthesis and Applications
- Rheumatoid Arthritis Research and Therapies
- Recycling and Waste Management Techniques
- Prion Diseases and Protein Misfolding
- Iron Metabolism and Disorders
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Radiopharmaceutical Chemistry and Applications
- Mass Spectrometry Techniques and Applications
- MicroRNA in disease regulation
- Graphite, nuclear technology, radiation studies
- Bone and Joint Diseases
- Bone health and osteoporosis research
Shanghai Jiao Tong University
2019-2025
Guangdong Academy of Sciences
2018-2025
Institute of Microbiology
2018-2025
Chongqing Medical University
2023-2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2023-2025
Hong Kong Polytechnic University
2022-2024
Shenyang Pharmaceutical University
2019-2024
Paul Scherrer Institute
2024
Southern Medical University
2020
Zhujiang Hospital
2020
In this study, 2-acrylamidophenylboronate (2-APB) was synthesised and its ability to bind with glucose investigated both in solution when integrated into a holographic sensor. Multiple forms of 2-APB, resulting from the neighbouring effect amido group boronic acid through an intramolecular B--O-coordinated interaction, were shown exist by using multinuclear NMR spectrometry. It found that 2-APB predominantly adopts zwitterionic tetrahedral form at physiological pH values. The complex...
Osteosarcoma is the most common type of bone cancer, especially in children and young adults. Recently, long noncoding RNAs (lncRNAs) have emerged as new prognostic markers gene regulators several cancers, including osteosarcoma. In this study, we investigated contributions lncRNA MALAT1 osteosarcoma with a specific focus on its transcriptional regulation interaction EZH2. Our results showed that was significantly increased specimens cell lines. ROC curve analysis had higher area under than...
Iron homeostasis is essential for maintaining cellular function in a wide range of cell types. However, whether iron affects the thermogenic properties adipocytes currently unknown. Using integrative analyses multi-omics data, transferrin receptor 1 (Tfr1) identified as candidate regulating thermogenesis beige adipocytes. Furthermore, it shown that mice lacking Tfr1 specifically have impaired thermogenesis, increased insulin resistance, and low-grade inflammation accompanied by deficiency...
Advances in next-generation sequencing (NGS) have revolutionized microbial studies many fields, especially clinical investigation. As the second human genome, microbiota has been recognized as a new approach and perspective to understand biological pathologic basis of various diseases. However, massive amounts data remain huge challenge researchers, those who are unfamiliar with analysis. The mathematic algorithm approaches introduced from another scientific field will bring bewildering...
This study explores the effectiveness of radiografted chelating adsorbents for recovery rhodium (Rh) from acidic wastewater, focusing on functionalized materials with and without loaded silver (Ag). Platinum group metals (PGMs), particularly Rh, are essential yet rare, necessitating efficient methods industrial waste. Rh exhibits complex chemistry in environments, often complicating its extraction recovery. Traditional such as solvent ion exchange adsorption have limitations, prompting...
<title>Abstract</title> <bold>Background</bold> Oxidative stress (OS) induced by local reactive oxygen species (ROS) accumulation plays a vital role in initiating and accelerating intervertebral disc degeneration (IDD). Cerium oxide nanoparticles (CeNPs) have specific efficient catalytic activity for ROS. Its nanoscale particle size non-stringent reaction conditions might address challenges faced traditional antioxidants remaining stable when used the degenerative avascular (IVD)....
// Qingbo Li 1 , Xiaohan Pan 2 Xiqian Wang Xiejia Jiao Jiachun Zheng Zhiqiang and Yanqing Huo Department of Orthopedics, The Second Hospital Shandong University, Jinan, 250133, Province, China Health Management, Correspondence to: Huo, email: hyq_doctor@163.com Keywords: MALAT1, osteosarcoma, miR-205, proliferation, SMAD4 Received: April 21, 2017 Accepted: July 26, Published: September 06, ABSTRACT Increasing evidences have indicated that long non-coding RNAs (lncRNAs) play an important role...
The mechanical properties of SF nanofibrous matrices were enhanced through crosslinking with HA/EDC/NHS for soft tissue engineering.
Neural progenitor cells (NPCs) undergo rapid proliferation during neurulation. This growth generates a high demand for mRNA translation in timing-dependent manner, but its underlying mechanism remains poorly understood. Lin28 is an RNA-binding protein with two paralogs, Lin28a and Lin28b, mammals. Mice Lin28b deletion exhibit no developmental defects, whereas we previously reported that led to microcephaly. Here found Lin28a/b double knockout (dKO) mice displayed neural tube defects (NTDs)...
Abstract The cellular prion protein (PrP C ) is required for skeletal muscle function. Here, we report that a higher level of PrP accumulates in the cytoplasm six myopathy patients compared to controls. inhibits cell autophagy, and blocks myoblast differentiation. selectively binds subset miRNAs during differentiation, colocalization miR-214-3p was observed with excessive . We demonstrate overexpressed cells under pathological conditions, differentiation by physically interacting miRNAs,...