- Dermatologic Treatments and Research
- Facial Rejuvenation and Surgery Techniques
- melanin and skin pigmentation
- Hair Growth and Disorders
- Botulinum Toxin and Related Neurological Disorders
- Acute Ischemic Stroke Management
- Reconstructive Facial Surgery Techniques
- Cancer Diagnosis and Treatment
- Laser Applications in Dentistry and Medicine
- Acne and Rosacea Treatments and Effects
- Facial Nerve Paralysis Treatment and Research
- Genital Health and Disease
- Vascular Malformations and Hemangiomas
- Analytical Chemistry and Sensors
- Body Contouring and Surgery
- Autoimmune Bullous Skin Diseases
- Cutaneous lymphoproliferative disorders research
- Diagnosis and Treatment of Venous Diseases
- Venous Thromboembolism Diagnosis and Management
- Dialysis and Renal Disease Management
- Reconstructive Surgery and Microvascular Techniques
- Microfluidic and Capillary Electrophoresis Applications
- Systemic Sclerosis and Related Diseases
- Amoebic Infections and Treatments
- Ginkgo biloba and Cashew Applications
Chang Gung University of Science and Technology
2013-2023
Chang Gung University
2013-2023
Chang Gung Memorial Hospital
2013-2023
Xiamen Chang Gung Hospital
2020-2021
National Defense Medical Center
2017
Tri-Service General Hospital
2017
Keelung Chang Gung Memorial Hospital
2013
Cathay General Hospital
2008-2011
University of Cambridge
2004-2006
PA Consulting Group
2006
<h3>Importance</h3> Varicose veins are common but rarely associated with serious health risks. Deep venous thrombosis (DVT), pulmonary embolism (PE), and peripheral artery disease (PAD) also vascular diseases systemic effects. Little is known about the association between varicose incidence of other including DVT, PE, PAD. <h3>Objective</h3> To investigate whether an increased risk or <h3>Design, Setting, Participants</h3> A retrospective cohort study using claims data from Taiwan’s National...
Abstract Common genetic variants that increase the risk for Parkinson's disease may differentiate patient subgroups and influence future individualized therapeutic strategies. Herein we show evidence leucine‐rich repeat kinase 2 (LRRK2) c.4883G>C (R1628P) as a factor in ethnic Chinese populations. A study of 1,986 individuals from 3 independent centers Taiwan Singapore demonstrates Lrrk2 R1628P increases (odds ratio, 1.84; 95% confidence interval, 1.20–2.83; p = 0.006). Haplotype analysis...
A glucose sensor comprising a reflection hologram incorporated into thin, acrylamide hydrogel film bearing the cis-diol binding ligand, 3-acrylamidophenylboronic acid (3-APB), is described. The diffraction wavelength (color) of changes as polymer swells upon cis-diols. effect various concentrations glucose, variety mono- and disaccharides, α-hydroxy acid, lactate, on holographic response was investigated. displayed reversible in function concentration, with sensitivity system being dependent...
In this study, 2-acrylamidophenylboronate (2-APB) was synthesised and its ability to bind with glucose investigated both in solution when integrated into a holographic sensor. Multiple forms of 2-APB, resulting from the neighbouring effect amido group boronic acid through an intramolecular B--O-coordinated interaction, were shown exist by using multinuclear NMR spectrometry. It found that 2-APB predominantly adopts zwitterionic tetrahedral form at physiological pH values. The complex...
Atrophic facial acne scars is one of the most common problems in patients with inflammatory acne. Ablative laser resurfacing has unpleasant complications and a long recovery period. Nonablative therapies yield less improvement satisfaction. The introduction fractional photothermolysis (FP) an alternative treatment for atrophic scars.To evaluate effectiveness safety nonablative 1,550-nm erbium-doped fiber FP session.Forty-five (skin type III-IV, mean age 29) were enrolled study. Each patient...
Abstract Background Dark eye circle ( DEC ) is a common problem that usually lacks detailed classification in the etiology and structural variations. A newly‐developed Assessment Score using Wood's lamp ultrasonogram will provide more precise evaluation of for improving treatment results. Materials methods Sixty‐five cases, including eight males 57 females with mean age 38.9 years, were enrolled. classified into pigmented (brown), vascular (blue to purple), structural, mixed type by...
In recent years, using the 1,064-nm Q-switched neodymium-doped yttrium aluminium garnet (Nd:YAG) laser (QSNYL) with or without exogenous topical carbon solution application for facial skin rejuvenation has become popular in Southeast Asia, but there not been any published clinical report discussing effect of QSNYL Asian patients.To evaluate efficacy improvement pore size, sebaceous secretion, texture, and tone patients. We also observed whether is enhancement before therapy.Twenty-four...
Background and Objectives The picosecond (PICO) laser has been a new promising device. But, so far, there have not many prospective studies investigating the efficacy in acne scar treatment. This study evaluated safety of dual‐wavelength treatment scar. Study Design/Materials Methods A total 20 patients with skin type III–IV were enrolled this study. Eighteen completed All six sessions within 1‐month interval. treated using both 532 1,064 nm fractionated handpieces. In evaluation, Goodman...
Background: Varicose veins are a common problem worldwide. Although it was reported that varicose have cosmetic and symptomatic effects can also lead to an increased risk of incident deep venous thrombosis, pulmonary embolism, peripheral artery disease, whether vein treatment prevents those serious complications is unknown. Methods: This retrospective cohort study used claims data extracted from the Chang Gung Research Database National Health Insurance in Taiwan. The subjects were patients...
Abstract Background Lower blepharoplasty is a common cosmetic operation that relies on minimal postoperative scarring, but Asian patients are at higher risk than Caucasians for hypertrophic and/or widened scars. Botulinum toxin type A (BTX) injections widely employed to alleviate dynamic facial rhytids and also can improve scar quality by reducing tension. The authors assessed whether simultaneous transcutaneous lower BTX could subciliary quality. Objectives objective of this study was...
BACKGROUND This investigation reports a 68-year-old man with history of hepatocellular carcinoma (HCC) diagnosed 2 years previously who developed single, easy-bleeding, pyogenic granuloma (PG)-like lesion on his right upper abdomen, located in the area previous therapeutic percutaneous ethanol injection (PEI) for HCC treatment. The 3 months after injection. tumor was found to be identical HCC. OBJECTIVE To describe case cutaneous seeding during PEI presented as PG-like lesion. our knowledge,...
The follicular unit transplantation strip harvesting surgery is one of the gold standard methods hair transplantation; counting ratio and density a major step in donor site evaluation.We conducted study for analyzing preoperative evaluation comparison actual harvested estimated units transplantation.In this retrospective study, we enrolled 65 male patients with androgenetic alopecia who underwent transplantation. Before procedure, counted calculated percentage each unit. And then, compared...
Lower eyelid aging is a complicated process, and for that reason, comprehensive assessment of the lower important before treatment.This study was conducted to analyze assess process between different age groups Asian women.The authors developed rating scale (CLEARS). The contains 3 domains each composed items. Individuals were evaluated by group starting with third decade (20-29 years) through seventh (60-69 2 dermatologists working independently.A total 114 cases evaluated. scores CLEARS...
Melasma is a common acquired facial hypermelanosis with irregular brownish macules and patches. The clinical course often fluctuated refractory to treatment. present study was conducted evaluate the efficacy safety of pulsed alexandrite laser for treatment melasma.In study, we enrolled Asian patients melasma. All received four monthly treatments laser. severity melasma evaluated by blinded dermatologist, using Modified Area Severity Index (MMASI), patient assessment, visual analogue scale,...