A5029245192- Transcranial Magnetic Stimulation Studies
- Stroke Rehabilitation and Recovery
- Acute Ischemic Stroke Management
- Facial Nerve Paralysis Treatment and Research
- Ear Surgery and Otitis Media
- Functional Brain Connectivity Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurosurgical Procedures and Complications
- Neuroscience and Neuropharmacology Research
- Vestibular and auditory disorders
- Dialysis and Renal Disease Management
- Muscle activation and electromyography studies
- Mitochondrial Function and Pathology
- Voice and Speech Disorders
- Ear and Head Tumors
- Trigeminal Neuralgia and Treatments
- Head and Neck Surgical Oncology
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Neuroscience and Neural Engineering
- Migraine and Headache Studies
- Epilepsy research and treatment
- EEG and Brain-Computer Interfaces
- Pain Management and Treatment
- Motor Control and Adaptation
- Moyamoya disease diagnosis and treatment
I-Shou University
2006-2023
National Yang Ming Chiao Tung University
2020-2023
E-Da Hospital
2004-2023
Taipei Veterans General Hospital
2021
China Medical University Hospital
2017
China Medical University
2017
Chiayi Chang Gung Memorial Hospital
2004
University of Iowa
1997
Kaohsiung Chang Gung Memorial Hospital
1993-1994
Abstract Background Bihemispheric transcranial direct current stimulation (tDCS) of the primary motor cortex (M1) can simultaneously modulate bilateral corticospinal excitability and interhemispheric interaction. However, how tDCS affects subacute stroke recovery remains unclear. We investigated effects bihemispheric on in patients. Methods enrolled inpatients who had first-ever ischemic at subcortical regions moderate-to-severe baseline Fugl-Meyer Assessment Upper Extremity (FMA-UE) score...
Summary: Purpose: Prolonged and continuous epileptic seizure (status epilepticus) results in cellular changes that lead to neuronal damage. We investigated whether these entail mitochondrial dysfunction ultrastructural damage the hippocampus, by using a kainic acid (KA)‐induced experimental status epilepticus model. Methods: In Sprague–Dawley rats maintained under chloral hydrate anesthesia, KA (0.5 nmol) was microinjected unilaterally into CA3 subfield of hippocampus induce seizure‐like...
Abstract Background Dual transcranial direct current stimulation (tDCS) to the bilateral primary motor cortices (M1s) has potential benefits in chronic stroke, but its effects subacute when behavioural might be expected greater, have been relatively unexplored. Here, we examined neurophysiological and factors influencing responsiveness of dual-tDCS stroke survivors. Methods We conducted a randomized sham-controlled crossover study 18 survivors with first-ever, unilateral subcortical...
Tolosa-Hunt syndrome (THS) manifests as a benign or an inflammatory type disease. The nosography differences between these types remain to be elucidated. We aimed analyze and compare the clinical presentations of THS.The ward patients who presented with THS from January 1990 May 2011 were retrospectively reviewed. was diagnosed according recommendations International Headache Society.Of 53 cases (49 patients), 30 (56.6%) classified 23 (43.4%) THS. There strong similarities groups in terms...
The relationship between cholesterol level and hemorrhagic stroke is inconclusive. We hypothesized that low levels may have association with intracerebral hemorrhage (ICH) severity at admission 3-month outcomes. This study used data obtained from a multi-center registry program in Taiwan. categorized acute spontaneous ICH patients, based on their baseline of total (TC) measured admission, into 3 groups <160, 160-200 >200 mg/dL TC. evaluated risk having initial severity, National Institutes...
Status epilepticus may cause molecular and cellular events, leading to hippocampal neuronal cell death. Peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) is an important regulator of vascular endothelial growth factor (VEGF) VEGF 2 (VEGFR2), also known as fetal liver kinase 1 (Flk-1). Resveratrol activator PGC-1α. It has been suggested provide neuroprotective effects in epilepsy, stroke, neurodegenerative diseases. In the present study, we used microinjection kainic acid...
Abstract We report a family with familial amyloid polyneuropathy (FAP), showing an early‐onset and fatal outcome before age 30. Transthyretin (TTR) gene analysis showed one point mutation (T → C change) in the second base of codon 55, corresponding amino acid substitution proline (Pro) for leucine (Leu) was confirmed at protein level. This is first FAP Taiwanese origin demonstrating causative abnormality, TTR‐Pro 55 considered to be more serious compared other forms FAP. © 1994 John Wiley...
One of the factors that induces eustachian tube dysfunction caused by invasion nasopharyngeal carcinoma is paralysis tensor veli palatini muscle. Electromyography (EMG), computed tomography (CT), and/or magnetic resonance imaging (MRI) were used to study muscle and related paratubal structures parapharyngeal space. This study, from 44 patients with carcinoma, showed 67% muscles on side symptomatic ear yielded abnormal electromyographic waveforms, which usually indicated a neurogenic...
Abstract Epilepsy and spreading depolarization (SD) are both episodic brain disorders often exist together in the same individual. In CA1 pyramidal neurons of mouse hippocampal slices, induction SD evoked epileptiform activities, including ictal-like bursts, which occurred during repolarizing phase SD, subsequent generation paroxysmal shifts (PDSs), characterized by mild plateau with overriding spikes. The duration activity was correlated recovery time potential whereas parameters PDSs were...
Cerebrospinal fluid (CSF) leak can be spontaneous or nonspontaneous. The management options include conservative treatments, blood patch, and surgical repairs. We compared clinical symptoms, image findings, options, hospitalization, relapse rates among different causes of CSF leaks. Eighty-one patients were recruited: 20 with 61 nonspontaneous Nonspontaneous included lumbar puncture, surgery, trauma. Surgery sites comprised sphenoid, spine, skull base, calvaria. Spontaneous came from the...
To research the pathophysiology of Eustachian tube (ET), electromyographies (EMG) tensor and levator veli palatini muscles (TVP LVP) in 46 fresh specimens nasopharyngeal carcinoma (NPC) were studied.Sixty-eight percent TVP on symptomatic side had abnormal EMG. Normal EMG recordings noted all asymptomatic side. The observed most often was poor interference pattern or decreased with swallowing, not uncommonly, there some motor unit action potentials serrated large polyphasic waveforms found...
Many Chinese like to drink alcohol soaked with creatures for promoting health. This study reports a 49‐year‐old male who presented multiple focal neuropathies of the upper limbs, coagulopathy, erythematous swelling bilateral extremities and trunk bullous skin lesions, rhabdomyolysis associated acute renal failure after drinking centipede. Soaking centipede, Scolopendra subspinipes mutilans, in 53% alcohol, produced wine. Supportive treatment was administered, lesions improved subsequent...