A5038150368- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Atrial Fibrillation Management and Outcomes
- Blood Coagulation and Thrombosis Mechanisms
- Pulmonary Hypertension Research and Treatments
- Diagnosis and Treatment of Venous Diseases
- Central Venous Catheters and Hemodialysis
- Mechanical Circulatory Support Devices
- Acute Myocardial Infarction Research
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Poisoning and overdose treatments
- Drug-Induced Hepatotoxicity and Protection
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Medical Imaging and Pathology Studies
- Thermal Regulation in Medicine
- Non-Invasive Vital Sign Monitoring
- Cardiac electrophysiology and arrhythmias
- Injury Epidemiology and Prevention
- Public Administration and Political Analysis
- Heart Failure Treatment and Management
- Trauma and Emergency Care Studies
- Antibiotics Pharmacokinetics and Efficacy
Mie University
2010-2024
Mie University Hospital
2013-2024
Weatherford College
2021
Suzuki (Japan)
2021
Yokohama National University
2020
Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences
2009
Kyushu University
2004
Pulmonary arterial hypertension (PAH) is a poor prognostic disease with limited treatment options. Rho-kinase involved in the pathophysiology of several diseases underlying smooth muscle hypercontraction, so purpose this study was to investigate efficacy fasudil, inhibitor, patients PAH.Fasudil 30 mg intravenously injected over min 8 (all female, mean +/- SD, 41+/-11 years) PAH. The lowest total pulmonary resistance (TPR) time within 30-60 after administration. Administration fasudil...
Summary There are three different diagnostic score systems for disseminated intravascular coagulation (DIC) established by the Japanese Ministry Health and Welfare (JMHW), International Society on Thrombosis Haemostasis (ISTH) Association Acute Medicine (JAAM). The JMHW criteria still used in Japan. In present study, all were to prospectively evaluate 413 patients with underlying diseases of DIC who treated at Mie University Hospital (JMHW, n= 166; ISTH, n=143; JAAM, n=291). odds ratio (95%...
To investigate the association between regional brain oxygen saturation (rSO2) at hospital arrival and neurological outcomes 90 days in patients with out-of-hospital cardiac arrest (OHCA).The Japan-Prediction of Outcomes post (J-POP) registry is a prospective, multicenter, cohort study to test whether rSO2 predicts after OHCA. We measured OHCA immediately using near-infrared spectrometer placed on forehead non-blinded fashion. The primary endpoint was "neurological outcomes" OHCA.EMS...
Prothrombin fragment 1 + 2 (F1 2) is considered to be useful for diagnosis of thrombosis. However, the evidence a thrombosis by F1 still not well established. The plasma concentrations 2, soluble fibrin, D-dimer, and thrombin-antithrombin complex were measured in 694 patients suspected having then correlated with Plasma significantly higher thrombosis, compared without When cutoff values more than 300 pmol/L used diagnosis, 50% thus found have findings showed that similar diagnostic ability....
Background: Circumstances and outcomes of out-of-hospital cardiac arrest (OHCA) in elementary middle school students while at the era public-access defibrillation are unknown. Methods Results: We conducted a nationwide hospital-based survey who had OHCA origin received prehospital resuscitation 2005–2009. Among 58 cases recruited, 90% were witnessed by bystanders; 86% ventricular fibrillation as initial rhythm; 74% resuscitated 24% defibrillated 55% occurred school; 66% exercise-related; 48%...
Background: Although stent implantation is used worldwide for peripheral arterial disease, there little data on the safety and long-term patency of stents implanted venous disease. Methods Results: We studied 13 patients with 14 lesions (6 males, 7 females, mean age: 63.2±10.2 years) diagnosed stenosis who underwent stenting. examined location stenosis, stenting, success rate, rate. All were suffering from in left common iliac vein because compression syndrome. No major complications...
Background The purpose of this study was to assess the use Günther Tulip Filter (GTF) for management venous thromboembolism (VTE). Methods and Results Between December 2000 April 2005, 118 patients (42 males, 76 females; mean age 60.5 years) diagnosed with VTE, underwent treatment a GTF. filter left permanently in 52 patients. In other 66 patients, attempts were made retrieve it, success 60 cases (90.9%). No major complication found throughout filter's use. Of 58 permanent filters, 41...
Elevated levels of factor VIII (FVIII) have been suggested as important for the pathogenesis venous thromboembolism (VTE). The objective this study was to explore association between elevated FVIII level and VTE in Japan.68 patients with objectively documented 40 controls were included. In patients, measured a mean follow-up period 52.6 months (3-348 months) after onset VTE, order avoid an acute-phase response. had higher than (154.5 ± 55.8 IU/dl vs. 114.3 16.0 IU/dl, P < 0.0001). According...
AimOur study aimed at filling the fundamental knowledge gap on characteristics of regional brain oxygen saturation (rSO2) levels in out-of-hospital cardiac arrest (OHCA) patients with or without return spontaneous circulation (ROSC) upon arrival hospital for estimating quality cardiopulmonary resuscitation and neurological prognostication these patients.MethodsWe enrolled 1921 OHCA from Japan – Prediction Neurological Outcomes Patients Post-cardiac Arrest Registry measured their rSO2...
The present study was designed to determine the cutoff values of D-dimer and soluble fibrin (SF) for diagnosis deep venous thrombosis (DVT) pulmonary embolism (PE) in Japanese patients. Plasma levels these molecules were measured 243 patients suspected having DVT 100 healthy volunteers (controls). Out patients, 20 diagnosed with DVT. In control group, plasma SF did not show normal distribution, 95% confidence intervals (CI) 2.45 μg/mL 6.92 μg/mL, respectively. significantly higher than those...
The aim of this study was to clarify the incidence and clinical predictors deep vein thrombosis (DVT) in patients with congestive heart failure (CHF) Japan.Between January 2003 2008, 161 were admitted Mie University Hospital a diagnosis CHF underwent venous compression ultrasonography. Of them, 18 (11.2%) diagnosed DVT. As defined by New York Heart Association (NYHA) functional class, class IV had higher rate DVT than those II or III (class II: 3 (4.4%), III: 2 (4.8%), IV: 13 (25.5%),...
Extracorporeal cardiopulmonary resuscitation (ECPR) is being used increasingly in the emergency and critical care field Japan. A major complication of ECPR bleeding; however, optimal initial heparin dose activated coagulation time (ACT) remain unknown. The aim this study was to assess appropriateness our anticoagulation protocol.We retrospectively evaluated dose, ACT value, incidence bleeding thrombotic complications post-cardiopulmonary arrest patients who received a fixed, body...
The simple risk index recorded in the emergency room (ER-SRI), which is calculated using formula (heart rate × [age / 10]
Abstract The present study was designed to determine the prevalence of lupus anticoagulant (LA) antibody and several antibodies for antiphospholipid syndrome (APS) in patients with deep vein thrombosis (DVT)/pulmonary embolism (PE) ( n = 48), cerebral (CT, 30), systemic erythematosus (SLE, 22), idiopathic thrombocytopenic purpura (ITP, 30). presence examined by using respective ELISA kits. LA positive 38.6% DVT/PE, suggesting that is one most important risk factors DVT/PE. highest anti‐β 2...
The aim of this study was to compare the prognosis and time reduction between helicopter emergency medical services (HEMS) with a physician ground (GEMS) in acute myocardial infarction (AMI) cases.This is registry-based Japan Helicopter Emergency Medical Service Registry from April 1, 2015, March 31, 2018.A total 605 cases AMI were registered HEMS group 794 GEMS group. In non-cardiopulmonary arrest (CPA), did not differ significantly. Regarding road distance, for ranges 20 40 km > km, times...
Introduction: Less than 10% of unnatural death cases have been examined by autopsy in Japan. In particular, the causes elderly not yet actively investigated. Here, we evaluated possible use postmortem computed tomography (PMCT) to investigate sudden unexpected natural (SUND) elderly. Methods and subjects: Death confirmed within 24 hours since onset symptoms at Emergency Department Mie University Hospital were defined as cases. A total 212 cases, including 175 SUND that occurred a 3-year...