A5056192249- Polyomavirus and related diseases
- SARS-CoV-2 and COVID-19 Research
- Viral gastroenteritis research and epidemiology
- SARS-CoV-2 detection and testing
- Full-Duplex Wireless Communications
- Antenna Design and Analysis
- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Energy Harvesting in Wireless Networks
- Hepatitis Viruses Studies and Epidemiology
- Water Treatment and Disinfection
- Wastewater Treatment and Reuse
- Aquatic Invertebrate Ecology and Behavior
- Environmental Toxicology and Ecotoxicology
- Evolution and Genetic Dynamics
- Medical Imaging Techniques and Applications
- COVID-19 Clinical Research Studies
- Hepatitis C virus research
- Cancer, Lipids, and Metabolism
- Ga2O3 and related materials
- School Health and Nursing Education
- HIV Research and Treatment
- Liver Diseases and Immunity
- Covalent Organic Framework Applications
- Membrane Separation Technologies
University of Coimbra
2011-2025
The complexity of water contaminants, both chemical and biological requires an efficient feasible treatment alternative. Herein, the photocatalytic ozonation using graphitic carbon nitride catalysts was effectively applied for elimination a mixture targeted Escherichia coli bacteria Human polyomavirus JC (JC virus) in real secondary wastewater. exfoliation compared prepared urea melamine as precursors. physical provided no significant enhancement urea-based catalyst, while improvement...
Oral squamous cell carcinoma (OSCC) is expected to rise ca. 40 % by 2040. Rosmarinic acid (RA) has been recognized for its anticancer properties, although role in OSCC neglected. This work exploits the activity of RA 2D and 3D models cells compel a roadmap properties. The results demonstrated that significantly reduced mass metabolic dose, time, cell-type-dependent manner, predominantly highly-invasive OSCC, without compromising normal mucosa therapeutic doses. decreased mitochondria...
Abstract JC virus (JCV) is ubiquitous in the human population, infecting children asymptomatically. After primary infection, JCV persists host throughout life and often excreted urine. Two hundred thirty‐four urine samples 78 serum samples, collected from 171 healthy individuals 63 patients infected with HIV, were used to characterize infection a Portuguese population. Using PCR, DNA was detected 38% of samples. A significant difference excretion rate observed between HIV (51%) (33%). The...
Water scarcity is one of the main problems this century. reclamation appears as an alternative due to reuse treated wastewater. Therefore, effluents treatment technologies (activated sludge, rotary biological discs, percolating beds) must be improved since they are not able remove emerging contaminants such enteric pathogens (bacteria and virus). These pollutants difficult from wastewater lead adverse consequences human health. Advanced oxidation processes, single catalytic ozonation, appear...
This work aims to evaluate the microbiological contamination of sewage sludge (SS) collected in urban wastewater treatment plants (WWTP) from Portugal. Two types SS were considered: mixed (UM) and anaerobic digestion (AD). The two samples characterized relation main physical chemical parameters, as well (Escherichia coli Salmonella spp). Then, sanitation tests conducted through thermal drying treatments. Towards a circular economy, industrial alkaline wastes (green liquor dregs - GLD, lime...
Genomic surveillance of SARS-CoV-2 in Portugal was rapidly implemented by the National Institute Health early stages COVID-19 epidemic, collaboration with more than 50 laboratories distributed nationwide.By applying recent phylodynamic models that allow integration individual-based travel history, we reconstructed and characterized spatio-temporal dynamics introductions dissemination Portugal.We detected at least 277 independent introductions, mostly from European countries (namely United...
1. Smith DB, Simmonds P, & International Committee on Taxonomy of Viruses Hepeviridae Study Group. Consensus proposals for classification the family Hepeviridae. J Gen Virol. 2014; 95: 2223-2232. Google Scholar
Dendritic cells (DCs) are the most specialized and proficient antigen-presenting cells. They bridge innate adaptive immunity display a powerful capacity to prime antigen-specific T The interaction of DCs with receptor-binding domain spike (S) protein from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is pivotal step induce effective against S protein-based vaccination protocols, as well SARS-CoV-2 virus. Herein, we describe cellular molecular events triggered by virus-like...
JC virus (JCV) is ubiquitous in the human population. Primary infection normally occurs during childhood and followed by a lifelong persistent infection. The main mode of transmission remains unknown. Several authors have hypothesized that JCV through respiratory route, secretions could represent possible source viral particles. present study intended to evaluate oropharyngeal fluids from patients infected with JCV, order ascertain if indeed constitute exposure this polyomavirus....
Introduction: Progressive Multifocal Leukoencephalopathy (PML) is a severe and often fatal CNS disease caused by JC human polyomavirus infection. Diagnosis of PML based upon suggestive clinical symptoms brain images, supported the presence virus genome in CSF samples. Objective: The main objective our study was search for an alternative method DNA detection samples, with sensitivity specificity characteristics close to that standard techniques, but feasible at any laboratory. Methods: In...
JC polyomavirus (JCPyV) is ubiquitous in the human population and causative agent of a rare, fatal demyelinating disease central nervous system named Progressive Multifocal Leukoencephalopathy (PML). The route JCPyV transmission remains unclear, but high values seroprevalence suggest an easy frequent mode, such as respiratory route.