A5049220907- Photochromic and Fluorescence Chemistry
- Radical Photochemical Reactions
- Advanced biosensing and bioanalysis techniques
- Carbon and Quantum Dots Applications
- Organic Chemistry Cycloaddition Reactions
- Biosensors and Analytical Detection
- Analytical chemistry methods development
- Synthesis of Organic Compounds
- Photoreceptor and optogenetics research
- Synthesis of Indole Derivatives
- Quantum Dots Synthesis And Properties
- Photopolymerization techniques and applications
- Oxidative Organic Chemistry Reactions
- Advanced Chemical Sensor Technologies
- Analytical Chemistry and Chromatography
- Mass Spectrometry Techniques and Applications
- Electrospun Nanofibers in Biomedical Applications
- bioluminescence and chemiluminescence research
- Blood groups and transfusion
- Molecular Sensors and Ion Detection
- SARS-CoV-2 detection and testing
- Plant chemical constituents analysis
- Porphyrin and Phthalocyanine Chemistry
- Luminescence and Fluorescent Materials
- Various Chemistry Research Topics
Polytechnic Institute of Porto
2018-2024
University of Minho
2006-2023
Universidade do Porto
2012
A highly sensitive fluorescence detection probe was developed by tailoring plastic antibodies on the external surface of aqueous soluble quantum dots (QDs). The target Myoglobin (Myo), a cardiac biomarker that quenched intrinsic fluorescent emission cadmium telluride (CdTe) QDs capped with mercaptopropionic acid (CdTe-MPA-QDs). were incubated protein and further modified molecularly-imprinted polymer (MIP) produced radical polymerization acrylamide bisacrylamide. main physical features...
In this work, the conjugation of molecularly imprinted polymers (MIPs) to quantum dots (QDs) was successfully applied in assembly an cellulose membrane [hydroxy ethyl (HEC)/MIP@QDs] for specific recognition cardiac biomarker myoglobin (Myo) as a sensitive, user-friendly, and portable system with potential point-of-care (POC) applications. The concept is use MIPs biorecognition elements, previously prepared on surface semiconductor cadmium telluride QDs detection particles. fluorescent...
Abstract The photoinduced release of several neurotransmitter amino acids (glycine, alanine, glutamic acid, β‐alanine and γ‐aminobutyric acid) was accomplished from ester cages based on a new photoremovable protecting group consisting coumarin built the julolidine nucleus, namely (11‐oxo‐2,3,5,6,7,11‐hexahydro‐1 H ‐pyrano[2,3‐ f ]pyrido[3,2,1‐ ij ]quinolin‐9‐yl)methyl group. Photolysis steady‐state sensitization studies revealed that active molecule occurred in short irradiation times at...
Abstract (6‐Methoxy‐2‐oxo‐2 H ‐naphtho[1,2‐ b ]pyran‐4‐yl)methyl esters of valine or phenylalanine as model bifunctional molecules were synthesised to assess its applicability a photocleavable protecting group for solution phase organic synthesis and in caging applications at longer wavelengths. The behaviour the corresponding derivatives towards photolysis was evaluated by irradiation 350 419 nm mixture HEPES buffer acetonitrile methanol photochemical reactor, followed HPLC/UV monitoring....
Cancer antigen 15-3 (CA 15-3) is a biomarker for breast cancer used to monitor response treatments and disease recurrence. The present work demonstrates the preparation application of fluorescent biosensor ultrasensitive detection CA protein tumor marker using mercaptopropionic-acid-functionalized cadmium telluride (CdTe@MPA) quantum dots (QDs) conjugated with antibodies. First, QDs were synthesized by hydrothermal route, resulting in spherical nanoparticles up 3.50 nm diameter....
Abstract In order to develop butyric acid photoactive prodrugs, new heteroaromatic conjugates based on oxygen and nitrogen were synthesised evaluated under irradiation at 254, 300, 350 419 nm. Light‐triggered uncaging of from the corresponding heterocyclic cages was achieved with complete release drug in short times. Naphtho[2,3‐ d ]oxazole, naphtho[1,2‐ 3‐oxo‐3 H ‐benzo[ f ]benzopyran, 2‐oxo‐2 h ]benzopyran 6‐oxo‐6 ‐benzopyrano[6,7‐ ]oxazole readily photolysed, best results obtained for...
A dual-emissive fluorescent probe was developed for the sensitive and selective detection of matrix metalloproteinase 7 (MMP7), a protein biomarker associated with pancreatic cancer. The ratiometric consisting blue emitting carbon dots (CDs) molecularly imprinted polymers (MIPs) previously assembled around red quantum (QDs) successfully combined MMP7 protein. concept is to use MIPs that function as biorecognition elements, conjugated cadmium telluride QDs, sensing system. fluorescence...