Laure Champ‐Rigot
A5053948267- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Cardiovascular Syncope and Autonomic Disorders
- Hormonal Regulation and Hypertension
- Neurological disorders and treatments
- Cardiac Structural Anomalies and Repair
- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Congenital Heart Disease Studies
- Heart Rate Variability and Autonomic Control
- Combustion and Detonation Processes
- Advanced MRI Techniques and Applications
- Obstructive Sleep Apnea Research
- Takotsubo Cardiomyopathy and Associated Phenomena
- Venous Thromboembolism Diagnosis and Management
- Blood Pressure and Hypertension Studies
- Transplantation: Methods and Outcomes
- ECG Monitoring and Analysis
- Antiplatelet Therapy and Cardiovascular Diseases
- EEG and Brain-Computer Interfaces
- Genetic Neurodegenerative Diseases
- Acute Myocardial Infarction Research
Université de Caen Normandie
2013-2025
Centre Hospitalier Universitaire de Caen
2010-2025
Normandie Université
2015-2025
Centre Hospitalier Universitaire de Tours
2020-2022
Thion Medical (France)
2020
Inserm
2020
Weatherford College
2019
Superior vena cava (SVC) isolation during atrial fibrillation catheter ablation is limited by the risk of collateral damage to sinus node and/or phrenic nerve. Due its tissue-specificity, we hypothesized feasibility and safety pulsed-field (PFA)-based SVC isolation.
There has been an increasing focus on integrated, multidisciplinary, and holistic care in the treatment of atrial fibrillation (AF). The 'Atrial Fibrillation Better Care' (ABC) pathway proposed to streamline integrated AF. We evaluated impact outcomes ABC adherent management a contemporary real-life European-wide AF cohort.Patients enrolled ESC-EHRA EURObservational Research Programme General Long-Term Registry with baseline data evaluate criteria available follow-up were considered for this...
Background: Recurrences of atrial fibrillation (AF) after pulmonary vein isolation (PVI) are mainly due to reconnection. However, a growing number patients have AF recurrences despite durable PVI. The optimal ablative strategy for these is unknown. We analyzed the impact current ablation strategies in large multicenter study. Methods: Patients undergoing redo and presenting PVI were included. freedom from arrhythmia vein-based, linear-based, electrogram-based, trigger-based compared....
The explosion of novel anticancer therapies has meant emergence cardiotoxicity signals including atrial fibrillation (AF). Reliable data concerning the liability drugs in inducing AF are scarce. Using World Health Organization individual case safety report database, VigiBase®, we aimed to determine association between and AF.A disproportionality analysis evaluating multivariable-adjusted reporting odds ratios for with their 99.97% confidence intervals was performed 176 U.S. Food Drug...
Pulmonary vein isolation (PVI) is well established as a primary treatment for atrial fibrillation (AF). The POLAR ICE study was designed to collect prospective real world data on the safety and effectiveness of POLARxTM cryoballoon PVI treat paroxysmal AF.POLAR ICE, prospective, non-randomized, multicenter (international) registry (NCT04250714), enrolled 399 patients across 19 European centers. Procedural characteristics, such time isolation, cryoablations per pulmonary (PV), balloon nadir...
Background: Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease, and sudden cardiac death represents an important mode in these patients. Data evaluating implantable cardioverter defibrillator (ICD) this patient population remain scarce. Methods: A Nationwide French Registry including all patients with tetralogy ICD was initiated 2010 by Institute Health Medical Research. The primary time to event end point from implantation first appropriate therapy. Secondary...
ABSTRACT Introduction Radiofrequency ablation is a cornerstone therapy for patients with ischemic cardiomyopathy (ICM) presenting ventricular tachycardia (VT). In this context, typically performed endocardially as first‐line approach. However, despite acute procedural success, the risk of recurrence remains high, potentially due to presence epicardial substrate. Several observational studies have suggested potential benefits endo‐epicardial approach in decreasing recurrence. EPIC‐VT trial...
Pulmonary vein isolation (PVI) using a cryoballoon is well-established for the treatment of paroxysmal atrial fibrillation (PAF). Compared to other available technologies, usage stable, low-pressure (POLARx, Boston Scientific) has demonstrated lower nadir temperatures and longer thawing times. However, 1-year efficacy safety still needs be proven. The aim POLAR ICE Study was evaluate outcomes ablation in patients with fibrillation. ICE, prospective, non-randomized, international, multicenter...
Abstract Aims Heart transplantation (HT) can be proposed as a therapeutic strategy for patients with severe refractory electrical storm (ES). Data in the literature are scarce and based on case reports. We aimed at determining characteristics survival of transplanted ES. Methods results Patients registered HT waiting list during following days after ES eventually transplanted, from 2010 to 2021, were retrospectively included 11 French centres. The primary endpoint was in-hospital mortality....
Sudden cardiac arrest remains a major complication of acute myocardial infarction (AMI) and is frequently related to ventricular fibrillation (VF). Incidence impact VF among patients hospitalized for AMI were evaluated.Data from the FAST-MI programme consisting 5 French nationwide prospective cohort studies between 1995 2015 analysed, totally including 14 423 with (66 ± years, 72% males, 59% ST-elevation infarction). Overall, proportion presenting in-hospital decreased 3.9% in 1.8% (P <...
Highly localized impedance (LI) measurements during atrial fibrillation (AF) ablation have the potential to act as a reliable predictor of durability lesions created.We aimed collect data on procedural parameters affecting LI-guided in large multicenter registry.A total 212 consecutive patients enrolled CHARISMA registry and undergoing their first pulmonary vein (PV) isolation for paroxysmal persistent AF were included.In all, 13,891 radiofrequency (RF) applications ≥3 s duration assessed....
Myocardial inflammation has been consistently associated with genetic arrhythmogenic cardiomyopathy (ACM) and it hypothesized that episodes mimicking acute myocarditis (AM) could represent early inflammatory phases of the disease.We evaluated temporal association between recurrent (RAM) later diagnosis a ACM.Between January 2012 December 2021, patients RAM no previous were included (Recurrent Acute Myocarditis Registry, NCT04589156). A follow-up visit including clinical evaluation, resting...
Takotsubo cardiomyopathy is a reversible frequently precipitated by sudden emotional or physical stress. The exact physiopathology still debated and may involve catecholamine-induced myocardial stunning. Alcohol withdrawal associated with an hyperadrenergic state be period at risk of cardiac events. We report 56-year-old man triggered alcohol withdrawal.[Alexandre J, Benouda L, Champ-Rigot Labombarda F. withdrawal. Drug Rev 2011;30:434–437]
After an old myocardial infarction (MI), patients are at risk for reentrant ventricular tachycardia (VT) due to scar tissue that can be accurately identified by late gadolinium enhancement cardiac magnetic resonance (LGE-CMR). Although the ability of LGE-CMR predict sustained VT in implantable cardioverter-defibrillator (ICD) recipients has been well established, its use monomorphic (sustained or not) cycle length (CL) and so, optimize ICD programming never investigated. We included...
Integrating remote monitoring (RM) into existing healthcare practice for heart failure (HF) patients to improve clinical outcome remains challenging. The ECOST-CRT study compared the of a comprehensive RM scheme including patient questionnaire capturing signs and symptoms HF notifications specific parameters traditional in with cardiac resynchronization therapy (CRT) devices. Patients were randomized 1:1 standard daily (notification technical ventricular arrhythmias; control group) or...
Abstract Aims Limited data exist concerning fragmented QRS complexes (fQRSs) on the surface electrocardiogram (ECG) of apparently healthy athletes. We aimed to study prevalence and significance fQRS in lead V1 (fQRSV1), representing right ventricular (RV) activation, regarding training-induced RV morphological remodelling. Methods results Between January 2017 August 2019, 434 consecutive non-sedentary subjects underwent preparticipation cardiovascular screening, including a 12-lead ECG....
The left ventricular ejection fraction (LVEF) is the key selection criterion for an implanted cardioverter defibrillator (ICD) in primary prevention of sudden cardiac death. LVEF usually assessed by two-dimensional echocardiography, but cardiovascular magnetic resonance (CMR) imaging increasingly used. aim our study was to evaluate whether assessment using CMR (CMR-LVEF) or echocardiography (2D echo-LVEF) may predict differently occurrence clinical outcomes.