- Nanoparticles: synthesis and applications
- Nanoparticle-Based Drug Delivery
- Coagulation and Flocculation Studies
- Carbon and Quantum Dots Applications
- Electrostatics and Colloid Interactions
- Surfactants and Colloidal Systems
- Gold and Silver Nanoparticles Synthesis and Applications
- Iron oxide chemistry and applications
- Diffusion Coefficients in Liquids
- Heme Oxygenase-1 and Carbon Monoxide
- Arsenic contamination and mitigation
- Advanced Polymer Synthesis and Characterization
- Dendrimers and Hyperbranched Polymers
- Nanopore and Nanochannel Transport Studies
- Geochemistry and Elemental Analysis
- Pickering emulsions and particle stabilization
- Air Quality and Health Impacts
- Field-Flow Fractionation Techniques
- Spectroscopy and Quantum Chemical Studies
- Particle Dynamics in Fluid Flows
- Proteins in Food Systems
- Force Microscopy Techniques and Applications
- Heavy Metal Exposure and Toxicity
- Polymer composites and self-healing
- Thermography and Photoacoustic Techniques
Adolphe Merkle Institute
2015-2019
University of Fribourg
2015-2019
Fribourg Development Agency
2015-2019
Philipps University of Marburg
2015
Abstract As a highly interdisciplinary field, working with nanoparticles in biomedical context requires robust understanding of soft matter physics, colloidal behaviors, nano-characterization methods, biology, and bio-nano interactions. When reporting results, it can be easy to overlook simple, seemingly trivial experimental details. In this context, we set out understand how vitro technique, specifically the way administer particles 2D culture, influence outcomes. Gold coated...
As the commercial use of synthetic amorphous silica nanomaterials (SiO2-NPs) increases, their effects on environment and human health have still not been explored in detail. An often-insurmountable obstacle for SiO2-NP fate hazard research is challenging analytics solid particulate species, which involves toxic corrosive hydrofluoric acid (HF). We therefore developed validated a set simple acid-free sample preparation methods quantification SiO2 micro- nanoparticles. To circumvent HF, we...
Size polydispersity is a common phenomenon that strongly influences the physicochemical properties of nanoparticles (NPs). We present an analytical approach universally applicable to characterizing optically anisotropic round NPs and determines directly number-averaged size distribution via depolarized dynamic light scattering (DDLS). To demonstrate, we use aqueous suspensions Au different sizes surface functionalization.
Little is known about the simultaneous uptake of different engineered nanoparticle types, as it can be expected in our daily life. In order to test such co-exposure effects, murine macrophages (J774A.1 cell line) were incubated with gold (AuNPs) and iron oxide nanoparticles (FeO x NPs) either alone or combined. Environmental scanning electron microscopy revealed that single NPs both types bound within minutes on surface but a distinctive difference between FeO AuNPs. Uptake analysis studies...
We show that the statistical analysis of photon counts in depolarized dynamic light scattering experiments allows for accurate characterization rotational Brownian dynamics particles. Unlike correlation spectroscopy, technique is even at low temporal resolution and enables discontinuous data acquisition, which offers several advantages. To demonstrate usefulness method, we present a case study analyze aqueous suspensions tunicate cellulose nanocrystals silica particles, discuss aspects are...
Polymers with pendant ligands furnish single-chain polymeric nanoparticles upon intramolecular metal–ligand complex formation different metal-ions and Taylor dispersion analysis is employed to reliably characterize the dispersed particles.
Inhalation of combustion-derived ultrafine particles (≤0.1 μm) has been found to be associated with pulmonary and cardiovascular diseases. However, correlation the physicochemical properties carbon-based such as surface charge agglomeration state adverse health effects not yet established, mainly due limitations related detection carbon in biological environments. The authors have therefore applied model mimics simplified derived from incomplete combustion, namely, nanodots (CNDs) different...