- Advanced Radiotherapy Techniques
- Drug Solubulity and Delivery Systems
- Radiation Therapy and Dosimetry
- Drug Transport and Resistance Mechanisms
- Neuropeptides and Animal Physiology
- RNA Interference and Gene Delivery
- Medical Imaging Techniques and Applications
- Advanced Drug Delivery Systems
- Radiation Dose and Imaging
- Microbial Natural Products and Biosynthesis
- Peptidase Inhibition and Analysis
- Cannabis and Cannabinoid Research
- Radiomics and Machine Learning in Medical Imaging
- Neuroscience and Neuropharmacology Research
- Nanoplatforms for cancer theranostics
- Barrier Structure and Function Studies
- Nanoparticle-Based Drug Delivery
- Immunotherapy and Immune Responses
- Advanced X-ray and CT Imaging
- Fungal Biology and Applications
- Virus-based gene therapy research
- Gastrointestinal motility and disorders
- Analytical Chemistry and Chromatography
- Nicotinic Acetylcholine Receptors Study
- Signaling Pathways in Disease
Okayama University
2020-2025
Nagoya Institute of Technology
2023-2024
Kansai Medical University
2011-2021
University of Miyazaki
2021
Kumamoto University Hospital
1998-2020
Ritsumeikan University
2010-2014
Kumamoto University
2010
Kyoto Pharmaceutical University
2001-2009
Kyoto University
1993-2009
RIKEN
2007-2009
cDNAs representing the alpha subunit of polyomavirus enhancer binding protein 2 (PEBP2; also called PEA2) were isolated. The products are highly homologous to that Drosophila segmentation gene runt (run) for an N-proximal 128-amino acid region showing 66% identity. run homology encompasses domain capable a specific nucleotide sequence motif and dimerizing with companion beta subunit. human AML1 related t(8;21) acute myeloid leukemia had region. Together subunit, which increases affinity DNA...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTExcess and partial volumes of some alcohol-water glycol-water solutionsKoichiro Nakanishi, Nobuyuki Kato, Masato MaruyamaCite this: J. Phys. Chem. 1967, 71, 4, 814–818Publication Date (Print):March 1, 1967Publication History Published online1 May 2002Published inissue 1 March 1967https://pubs.acs.org/doi/10.1021/j100863a005https://doi.org/10.1021/j100863a005research-articleACS PublicationsRequest reuse permissionsArticle...
Targeting immune checkpoint proteins has recently gained substantial attention due to the dramatic success of this strategy in clinical trials for some cancers. Inducible T-cell co-stimulator ligand (ICOSLG) is a member B7 family regulatory ligands, expression which cancer implicated disease progression regulation antitumor adaptive immunity. Although aberrant ICOSLG been reported glioma cells, underlying mechanisms that promote glioblastoma (GBM) remain elusive.Here, we investigated causal...
The effects of nitric oxide (NO) donors NOC5 [3-(2-hydroxy-1-(methylethyl)-2-nitrosohydrazino)-1-propanamine ] and NOC12 [N-ethyl-2-(1-ethyl-hydroxy-2-nitrosohydrazino)-ethanamine] on the permeability 5(6)-carboxyfluorescein (CF) across intestinal membrane were examined by an in vitro Ussing chamber method. NO significantly increased CF their absorption-enhancing concentration-dependent over range 0.01 to 0.1 mM. Regional differences observed (colon > jejunum). effect reduced as molecular...
Laeverin/aminopeptidase Q (APQ) is a cell surface protein specifically expressed on human embryo-derived extravillous trophoblasts that invades the uterus during placentation. The cDNA cloning of Laeverin/APQ revealed sequence encodes with 990 amino acid residues, and contains HEXXHX18E gluzincin motif, which characteristic M1 family aminopeptidases, although exopeptidase motif family, GAMEN, uniquely substituted for HAMEN sequence. In this study, we recombinant using baculovirus expression...
GABA has important functions in brain plasticity related processes like memory, learning, locomotion and during the development of nervous system. It is synthesized by glutamic acid decarboxylase (GAD). There are two isoforms GAD, GAD1 GAD2, which encoded different genes. During embryonic transcription mRNA regulated alternative splicing several transcripts were distinguished human, mouse rat. Despite fact that structure gene been extensively studied, knowledge its exact structural...
Abstract Introduction Due to its spherical surface, scalp angiosarcoma requires careful consideration for radiation therapy planning and dose delivery. Herein, we investigated whether volumetric modulated arc (VMAT) is superior intensity (IMRT) in terms of the plan quality delivery time. Methods Three different coplanar treatment plans were created four patients, comprising a two‐arc VMAT as well 5‐field 9‐field IMRT with 6 MV beams. The X‐ray Voxel Monte Carlo algorithm was employed...