A5015892000- MicroRNA in disease regulation
- Autophagy in Disease and Therapy
- Cancer Immunotherapy and Biomarkers
- Histone Deacetylase Inhibitors Research
- Angiogenesis and VEGF in Cancer
- Pancreatic and Hepatic Oncology Research
- Cancer, Hypoxia, and Metabolism
- Cancer-related molecular mechanisms research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- Cancer-related gene regulation
- Circular RNAs in diseases
- Sarcoma Diagnosis and Treatment
- Protein Degradation and Inhibitors
- Hepatocellular Carcinoma Treatment and Prognosis
- Nutrition and Health in Aging
- Cancer Treatment and Pharmacology
- Extracellular vesicles in disease
- Cancer Mechanisms and Therapy
- CAR-T cell therapy research
- Estrogen and related hormone effects
- Cytokine Signaling Pathways and Interactions
- PARP inhibition in cancer therapy
- Ubiquitin and proteasome pathways
National and Kapodistrian University of Athens
2018-2025
Hospital Agioi Anargyroi
2025
Academy of Athens
2014-2025
Biomedical Research Foundation of the Academy of Athens
2025
Laiko General Hospital of Athens
2023
Athens Medical Center
2020
Molecular Oncology (United States)
2019
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies worldwide, while it persists as fourth most prevalent cause cancer-related death in United States America. Although there are several novel therapeutic strategies for approach this intensely aggressive tumor, remains a clinical challenge, hard to identify early stages, due its asymptomatic course. A diagnosis usually established when disease already late chemoresistance constitutes an obstacle optimal management...
Objectives: Autophagy plays a dual role in tumorigenesis. In the initial stages, it promotes cell survival and suppresses carcinogenesis, whereas cancer development, induces survival. this study, we investigate of autophagy as protective or tumor suppressor mechanism colorectal (CRC) lines evaluate its potential biomarker human samples. Materials Methods: The data 68 patients with CRC treated at our Department from January 1 to December 31, 2016 were analyzed. Immunohistochemistry evaluation...
The present cross-sectional prospective study (from January 2017 until December 2020) aimed to evaluate the interrelation between nutritional parameters at initial evaluation with changes in QOL indicators and Progression-Free Survival Overall 97 patients pancreatic cancer. Dietary risk assessments, an of Frailty Functional Status were performed. Health-related Quality Life was evaluated EORTC QLQ-C30 questionnaire. Nutritional risk, as by MNA-SF score, negatively associated age (p = 0.003)...
Ongoing research continues to elucidate the complex role of ephrin receptors (EPHs) and their ligands (ephrins) in breast cancer pathogenesis, with varying expression patterns implied have an important impact on patients' outcome. The current study aims investigate clinical significance EPHA2, EPHA4, EPHA7 triple-negative (TNBC) cases. protein was assessed immunohistochemically formalin-fixed paraffin-embedded (FFPE) TNBC tissue sections from 52 patients correlated key clinicopathologic...
Background/Aim: Triple negative breast cancer belongs to the most aggressive forms. Histone deacetylases (HDACs) constitute a class of enzymes that exhibit significant role in genesis and progression. In this study, we aimed at assessing clinical importance HDAC-2 triple cancer. Materials Methods: A total 138 specimens were examined on an immunohistochemical basis. statistical analysis was performed order examine association between survival clinicopathological features patients. Results:...