A5040944191- Advanced biosensing and bioanalysis techniques
- 14-3-3 protein interactions
- Ubiquitin and proteasome pathways
- Microbial Natural Products and Biosynthesis
- RNA Interference and Gene Delivery
- ATP Synthase and ATPases Research
- Mitochondrial Function and Pathology
- Monoclonal and Polyclonal Antibodies Research
- Identification and Quantification in Food
- DNA and Nucleic Acid Chemistry
- Genetic diversity and population structure
- Biosensors and Analytical Detection
- Pesticide Exposure and Toxicity
- Hemiptera Insect Studies
- Nanoplatforms for cancer theranostics
- Bacillus and Francisella bacterial research
- Phytoplasmas and Hemiptera pathogens
- Lepidoptera: Biology and Taxonomy
- Insect-Plant Interactions and Control
- Bacteriophages and microbial interactions
- Pesticide and Herbicide Environmental Studies
- Scarabaeidae Beetle Taxonomy and Biogeography
- Sulfur Compounds in Biology
- Forest Insect Ecology and Management
- Luminescence and Fluorescent Materials
Institute of Biophysics
2021-2024
Chinese Academy of Sciences
2021-2024
Renji Hospital
2018-2023
Shanghai Jiao Tong University
2018-2023
Ministry of Agriculture and Rural Affairs
2018-2020
Lanzhou University
2020
Huazhong University of Science and Technology
2013
Hong Kong University of Science and Technology
2013
Institute of Molecular Functional Materials
2013
University of Hong Kong
2013
Heteroptera, or true bugs, are the largest, morphologically diverse and economically important group of insects with incomplete metamorphosis. However, phylogenetic relationships within Heteroptera still in dispute most previous studies were based on morphological characters single gene (partial whole 18S rDNA). Besides, so far, divergence time estimates for totally rely fossil record, while no have been performed molecular rates. Here, first time, we used maximum parsimony (MP), likelihood...
Chitosan with tetraphenylethene pendants (TPE-CS) are synthesized by reaction between amine and isothiocyanate groups of chitosan (TPE), respectively. Nanoparticles TPE-CS (TPE-CS NPs) fabricated ionic gelation method. The NPs uniform in size, spherical shape, monodispersed, positive surface charge. suspension emits strong blue fluorescence under photoexcitation due to the aggregation-induced emission characteristics TPE moieties. can be internalized into cytoplasm through endocytosis...
ConspectusBacillus anthracis, present in two forms of vegetative cells and spores, is a pathogen that infects humans through contact with infected animals or contaminated animal products also maliciously used terrorist acts. Therefore, rapid sensitive test for B. anthracis necessary but challenging. The challenge comes from the following aspects: an accurate distinction other Bacillus species due to their high genomic similarity horizontal gene transfer between members; direct detection...
Switchable interfaces, also known as smart can alter their macroscopic properties in response to external stimuli. Compared an artificial switchable interface, DNA-based biointerfaces have high diversity, uniformity, reproducibility, and functionality are easily designed developed with atomic precision because the sequence of DNA strand strictly governs structural active its assembly. Moreover, various structures such double strands based on Watson–Crick base-pairing rule, G-quadruplexes,...
Glutathione (GSH), the constituent of redox buffer system, is a scavenger reactive oxygen species (ROS), and its ratio to oxidized glutathione (GSSG) key indicator oxidative stress in cell. Acute myeloid leukemia (AML) highly aggressive hematopoietic malignancy characterized by aberrant levels reduced GSH due stress. Therefore, real-time, dynamic, sensitive detection GSH/GSSG AML cells great interest for clinical diagnosis treatment leukemia. The application genetically encoded sensors...
To determine population genomic structure through high-throughput sequencing techniques has revolutionized research on non-model organisms. The coconut leaf beetle, Brontispa longissima (Gestro), is a widely distributed pest in Southern China. Here, we used restriction site-associated DNA (RAD) genotyping to assess the invasion pathway by detecting and estimating degree of genetic differentiation among 51 B. accessions collected from A total 10,127 SNPs were obtained, screened single...
Detection of viral infections (e.g., SARS-CoV-2) with high precision is critical to disease control and treatment. There an urgent need develop point-of-care detection methods complement the gold standard laboratory-based PCR assay comparable sensitivity specificity. Herein, we developed a method termed mCAD achieve ultraspecific SARS-CoV-2 RNA while maintaining by programming multiplex rolling circle amplification toehold-mediated strand displacement reactions. RCA offers sufficient targets...
The Epic® system, a high-throughput label-free optical biosensor is applied for the biochemical interrogation of phosphor-specific interactions 14-3-3 protein and its substrates. It has shown capability not only characterization binding rank affinity but also exploration potential interacting kinases A perspective applications diagnostics biomarker discovery, as well cell-based endogenous receptors viral infection characterization, are provided.
Here we sequenced and annotated the complete mitochondrial genome (mitogenome) of Illiberis ulmivora (Lepidoptera: Zygaenidae). This mitogenome was 15,334 bp long encoded 13 protein-coding genes (PCGs), 22 transfer RNA (tRNAs), 2 ribosomal unit (rrnL rrnS) a large non-coding region (putative control region). Compared with putative ancestral arrangement insects, gene rearrangements were found in two tRNA clusters (IQM ARNS1EF) I. mitogenome: changing trnI-trnQ-trnM to trnM-trnI-trnQ,...