Qingjie Ma
A5053762070- Thyroid Cancer Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Medical Imaging Techniques and Applications
- Nanoplatforms for cancer theranostics
- Medical Imaging and Pathology Studies
- Radiation Therapy and Dosimetry
- Nasolacrimal Duct Obstruction Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Photoacoustic and Ultrasonic Imaging
- Lung Cancer Treatments and Mutations
- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Extracellular vesicles in disease
- Corneal Surgery and Treatments
- Peptidase Inhibition and Analysis
- Advanced MRI Techniques and Applications
- Hydrogen's biological and therapeutic effects
- Sarcoma Diagnosis and Treatment
- Ophthalmology and Eye Disorders
Union Hospital
2015-2023
Jilin University
2013-2023
Union Hospital
2013-2022
Mudanjiang Medical University
2013
The phase II/III study of donafenib was initiated when there no available treatment indicated for Chinese patients with progressive radioactive iodine-refractory differentiated thyroid cancer (RAIR-DTC). Donafenib, an oral tyrosine kinase inhibitor (TKI), showed good efficacy and tolerability in the II study. We aimed to further evaluate antitumor activity safety RAIR-DTC.This multicenter, double-blind, placebo-controlled, III enrolled 191 RAIR-DTC randomized a ratio 2:1 (300 mg twice daily,...
Abstract Bioimaging guided‐radiotherapy is widely investigated as one of the mainstream cancer theranostic strategies for precision medicine. Nevertheless, background noise with “always‐on” imaging signal and inadequate tumor enrichment restrict disease diagnosis therapy. Here, a nanogapped gold nanoparticles (AuNNPs)–silver sulfide (Ag 2 S) vesicle (Ve) designed “biological switch” through self‐assembly pH‐responsive polymer thiolated polystyrene‐ co ‐poly(4‐vinylpyridine) grafted AuNNPs Ag...
The aim of the present study was to investigate inhibitory effects 90Sr-90Y β-irradiation in a rat model alkali burn-induced corneal neovascularization (CNV). Alkali CNV induced right eyes 30 female Wistar rats, which were randomly divided into following three groups (n=10/group): i) burn control group, received balanced salt solution treatment; ii) group 1, treatment with angiogenesis inhibitors; and iii) 2, treatment. A further 10 rats comprised blank only solution. Digital photographs...
<div>Abstract<p>Purpose: The phase II/III study of donafenib was initiated when there no available treatment indicated for Chinese patients with progressive radioactive iodine-refractory differentiated thyroid cancer (RAIR-DTC). Donafenib, an oral tyrosine kinase inhibitor (TKI), showed good efficacy and tolerability in the II study. We aimed to further evaluate antitumour activity safety RAIR-DTC patients. Patients Methods: This multicenter, double-blind, placebo-controlled, III...
<p>Figure S1: Thyroglobulin concentrations changes for individual patients with negative thyroglobulin antibody from baseline to the end of cycle 2.</p>
<p>Figure S1: Thyroglobulin concentrations changes for individual patients with negative thyroglobulin antibody from baseline to the end of cycle 2.</p>
Abstract Background: Radiation therapy is a main treatment option for cancer. Due to normal tissue toxicity, radiosensitizers are commonly used enhance RT. In particular, heavy metal or high-Z materials, such as gold nanoparticles, have been investigated radiosensitizers. So far, however, the related studies focused on spherical nanoparticles. this study, we assessed potential of ultra-thin nanowires radiosensitizer, which first time. Methods: Gold were synthesized by reduction HAuCl 4 in...
6095 Background: In the multicenter, double-blind, randomized, phase 3 REALITY study, apatinib significantly improved clinical benefits in terms of progression-free survival (PFS), overall (OS) and objective response rate (ORR) compared to placebo with a tolerable safety profile patients progressive locally advanced or metastatic radioactive iodine-refractory, differentiated thyroid cancer (RAIR-DTC). Here, we investigate association between baseline characteristics endpoints. Methods:...
<div>AbstractPurpose:<p>The phase II/III study of donafenib was initiated when there no available treatment indicated for Chinese patients with progressive radioactive iodine-refractory differentiated thyroid cancer (RAIR-DTC). Donafenib, an oral tyrosine kinase inhibitor (TKI), showed good efficacy and tolerability in the II study. We aimed to further evaluate antitumor activity safety RAIR-DTC.</p>Patients Methods:<p>This multicenter, double-blind,...
<p>Figure S1: Thyroglobulin concentrations changes for individual patients with negative thyroglobulin antibody from baseline to the end of cycle 2.</p>
<div>Abstract<p>Purpose: The phase II/III study of donafenib was initiated when there no available treatment indicated for Chinese patients with progressive radioactive iodine-refractory differentiated thyroid cancer (RAIR-DTC). Donafenib, an oral tyrosine kinase inhibitor (TKI), showed good efficacy and tolerability in the II study. We aimed to further evaluate antitumour activity safety RAIR-DTC patients. Patients Methods: This multicenter, double-blind, placebo-controlled, III...
<p>Figure S1: Thyroglobulin concentrations changes for individual patients with negative thyroglobulin antibody from baseline to the end of cycle 2.</p>
<div>AbstractPurpose:<p>The phase II/III study of donafenib was initiated when there no available treatment indicated for Chinese patients with progressive radioactive iodine-refractory differentiated thyroid cancer (RAIR-DTC). Donafenib, an oral tyrosine kinase inhibitor (TKI), showed good efficacy and tolerability in the II study. We aimed to further evaluate antitumor activity safety RAIR-DTC.</p>Patients Methods:<p>This multicenter, double-blind,...
<p>Figure S1: Thyroglobulin concentrations changes for individual patients with negative thyroglobulin antibody from baseline to the end of cycle 2.</p>
<p>Figure S1: Thyroglobulin concentrations changes for individual patients with negative thyroglobulin antibody from baseline to the end of cycle 2.</p>
To search for certain signature proteins and the expression profiles in lacrimal passage stenosis,rabbit models of stenosis were treated by 125I seed brachytherapy.All separated two-dimensional electrophoresis,and identified mass spectrometry.The results show that up-regulated are peptidyl-prolyl cis-trans isomerase A(PPIase A),and epidermal fatty acid-binding protein(E-FABP),while down-regulated myosin light chain 1(isomer skeletal muscle),myosin polypeptide 6(isomer 1 smooth muscle...
Objective To investigate the value of 99Tcm-HYNIC-(poly-(ethylene glycol),PEG) 4-E (PEG4-c(RGDfK))2 (99Tcm-3P4-RGD2) SPECT imaging in diagnosis SPN by visual and semiquantitative analysis.Methods Twenty-one patients (13 men,8 women; age range 37-77 (58±11) years)with observed on CT were analyzed prospectively.All underwent after administration 99Tcm-3P4-RGD2 with a dose (939 ± 118) MBq.The gold standard was based histopathological surgical samples from all recruited patients.The diagnostic...