A5100636722- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Thyroid Disorders and Treatments
- Radiation Dose and Imaging
- Radiopharmaceutical Chemistry and Applications
- Head and Neck Anomalies
- Hematopoietic Stem Cell Transplantation
- Medical Imaging Techniques and Applications
- Cardiac, Anesthesia and Surgical Outcomes
- Medical Imaging and Pathology Studies
- Gastric Cancer Management and Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Lung Cancer Diagnosis and Treatment
- Meningioma and schwannoma management
- Gallbladder and Bile Duct Disorders
- Medical Research and Treatments
- Cardiac Ischemia and Reperfusion
- Salivary Gland Tumors Diagnosis and Treatment
- Peptidase Inhibition and Analysis
- Pediatric Hepatobiliary Diseases and Treatments
- Pituitary Gland Disorders and Treatments
- Renal cell carcinoma treatment
- Sarcoma Diagnosis and Treatment
Sichuan University
2016-2025
West China Hospital of Sichuan University
2016-2025
Fuyang City People's Hospital
2019-2025
Zhengzhou University
2024
Second Hospital of Hebei Medical University
2024
Viva Biotech (China)
2024
Hebei Medical University
2024
Ningxia Medical University
2023
Capital Medical University
2010-2023
Beijing Chest Hospital
2023
Planar whole-body imaging with I-radiolabeled metaiodobenzylguanidine (I-MIBG) is routinely used in the follow-up evaluation of neuroblastoma. In recent years, SPECT integrated low-dose CT (SPECT/CT) has become more accessible. We investigated how much SPECT/CT can have additional diagnostic value over planar detection residual and recurrent neuroblastoma.A total 170 I-MIBG scans performed 147 patients known high-risk neuroblastoma were retrospectively analyzed. Regions increased uptake on...
Introduction: Cholesterol gallstone (CGS) is a biliary tract disorder requiring treatment in approximately 20% of patients. The efficacy Chaihu Shugan preventing CGS recurrence after successful remains uncertain. Methods: We examined the vivo preventive using mouse model and used multi-omics to study interplay between gut microbiota, metabolism, gene expression. Results: intestinal microbiota was severely dysregulated during formation CGS, showing marked decrease abundance beneficial...
Objective: This study aims to assess the clinical significance of peripheral blood neutrophil-to-lymphocyte ratio (NLR) in predicting chemotherapy outcomes for patients with small cell lung cancer (SCLC).Methods: A cohort 44 diagnosed SCLC between January 2021 June 2022 at Fuyang People's Hospital was selected analysis.All this group received a first-line platinum-based doublet regimen.In parallel, control consisting healthy individuals undergoing routine physical examinations same hospital...
ABSTRACT Background This study aimed to evaluate the correlation between number of examined lymph nodes (eLNs) and postoperative residual lateral LN disease in patients with papillary thyroid cancer (PTC) nodal metastasis (N1b) determine minimal threshold for eLNs. Methods Patients diagnosed unilateral N1b PTC who underwent total thyroidectomy therapeutic dissection central compartments January 2012 December 2022 were included. Multivariate logistic regression analyses performed identify...
Chronic inflammatory and immune dysregulation are critical drivers of the development progression chronic obstructive pulmonary disease (COPD). Posttranslational modifications, such as glycosylation Immunoglobulin G (IgG), crucial in modulating systemic homeostasis. This study aims to profile plasma IgG glycopeptides (IgGPs) COPD patients uncover new insights into their pathogenesis identify novel biomarkers. An integrated platform that combines Fe3O4@PDA@DETA nanospheres enrichment with...
In this study, vitamin C was administered at various times as a sour stimulant to thyroid cancer patients, and the effect on salivary absorbed dose of therapeutic radioiodine ((131)I) investigated.Patients with differentiated who had been prepared for remnant ablation after total thyroidectomy were prospectively recruited and, using random-number table, divided into 4 groups. hypothyroid condition, patients in groups A, B, C, D began sucking (100 mg every h daytime over 6 d) 1, 5, 13, 25 h,...
The aim of this study was to assess the prognostic value for NSCLC patients who were scheduled receive lung cancer radical resection.In cohort (Dec.2014-Feb.2016), with non-small cell (NSCLC) underwent thoracotomy enrolled and accessed at postoperative complications, one-year overall survival (OS) relapse-free (RFS). preoperative PLR NLR all calculated based on complete blood counts. Univariate multivariate Cox regression analyses performed determine associations OS RFS.A total 174 studied....
The purpose of this study was to evaluate whether a nodule with taller-than-wide shape (ie, an anteroposterior diameter that is longer than the transverse on or longitudinal plane [anteroposterior-to-transverse ratio] >1) good predictor papillary thyroid carcinoma (PTC) according size.We retrospectively examined 207 nodules in our hospital from September 2011 February 2013. Nodules were divided into groups by size: small (≤0.5 cm; group A), medium (0.5-1 B), and large (>1 C). Sonographic...
The phase II/III study of donafenib was initiated when there no available treatment indicated for Chinese patients with progressive radioactive iodine-refractory differentiated thyroid cancer (RAIR-DTC). Donafenib, an oral tyrosine kinase inhibitor (TKI), showed good efficacy and tolerability in the II study. We aimed to further evaluate antitumor activity safety RAIR-DTC.This multicenter, double-blind, placebo-controlled, III enrolled 191 RAIR-DTC randomized a ratio 2:1 (300 mg twice daily,...
Abstract Context The risk of persistent and recurrent disease in patients with differentiated thyroid cancer (DTC) is a continuum that ranges from very low to high, even within the 3 primary categories. It important identify independent clinicopathological parameters accurately predict clinical outcomes. Objective To examine association between pre-ablation stimulated thyroglobulin (ps-Tg) DTC investigate whether incorporation ps-Tg could provide more individualized estimate Design, Setting,...
Single nucleotide polymorphisms (SNPs) in the apolipoprotein A5 gene (APOA5) are associated with hypertriglyceridaemia our population. We studied associations of SNPs APOA5 metabolic syndrome (MetS) Hong Kong and Guangzhou Chinese.We genotyped five tagging 1330 unrelated subjects from Cardiovascular Risk Factor Prevalence Study cohort follow-up after a median interval 6·4 years; 1952 Biobank Cohort Study-Cardiovascular Disease Subcohort were used to replicate findings. The MetS was defined...
Abstract Objective Neck lymph node (LN) metastasis is a common feature of paediatric papillary thyroid cancer, and LN ratio (LNR) defined as the number positive LNs excised to total removed. Unlike in adults, few data are available regarding clinical implication LNR population. Our purpose was investigate association with outcomes cancer. Design & Methods The study retrospectively reviewed 136 consecutive children adolescents cancer involvement but no initial distant metastasis. Initial...
Abstract Testosterone replacement for older men is increasingly common, with some observations suggesting a protective effect on cognitive function. We examined the association of endogenous testosterone function among in Mendelian randomization study using separate-sample instrumental variable (SSIV) analysis estimator to minimize confounding and reverse causality. A genetic score predicting was developed 289 young Chinese from Hong Kong, based selected testosterone-related single...