A5101996539- Animal Nutrition and Physiology
- Meat and Animal Product Quality
- Genetic and phenotypic traits in livestock
- Aortic aneurysm repair treatments
- Ruminant Nutrition and Digestive Physiology
- Animal Behavior and Welfare Studies
- Adipose Tissue and Metabolism
- Reproductive Physiology in Livestock
- Pulmonary Hypertension Research and Treatments
- Cancer Cells and Metastasis
- Hormonal Regulation and Hypertension
- Biochemical Analysis and Sensing Techniques
- MicroRNA in disease regulation
- Muscle metabolism and nutrition
- Atherosclerosis and Cardiovascular Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Systemic Lupus Erythematosus Research
- Infectious Aortic and Vascular Conditions
- Gastrointestinal disorders and treatments
- Glycosylation and Glycoproteins Research
- Pancreatic and Hepatic Oncology Research
- Moyamoya disease diagnosis and treatment
- Biological Activity of Diterpenoids and Biflavonoids
- Nausea and vomiting management
- Diet, Metabolism, and Disease
Hunan Normal University
2019-2024
Jinzhou Medical University
2024
First Affiliated Hospital of Xi'an Jiaotong University
2023
Sun Yat-sen University
2022
Beijing Fengtai Hospital
2021
Wuhan Union Hospital
2021
Hubei University of Chinese Medicine
2021
Huanggang Central Hospital
2021
Guangdong Provincial Hospital of Traditional Chinese Medicine
2020
University of Kentucky
2002-2018
In humans, the incidence and severity of abdominal aortic aneurysms (AAA) are greater in males than females. Chronic infusion angiotensin II (AngII) into apolipoprotein E-deficient (apoE(-/-)) mice promotes atherosclerosis causes formation AAAs. Just as human more susceptible to developing AAAs, male AngII-induced We hypothesized that sex steroid hormones mediate gender differences AAA through regulation renin-angiotensin system. To define role ovarian hormones, female apoE(-/-) were...
Abstract This experiment was conducted to investigate the effects of different dietary energy levels on growth performance, slaughter traits, meat quality and blood biochemical parameters in fattening male Hu lambs. Sixty lambs were fed five iso‐protein diets which contained metabolizable a completely randomized design for 70 days. At end study, fifteen harvested further study. With increase level, daily weight gain dry matter intake extremely increased ( p < .001), feed conversion ratio...
This study evaluated the effects of dietary energy levels on growth performance, carcass traits, meat quality, and serum biochemical female Hu lambs. Seventy lambs (aged 4 months) were randomly allotted to 5 treatments. Lambs fed diets with metabolizable (ME): 9.17 (E1), 9.59 (E2), 10.00 (E3), 10.41 (E4), 10.82 MJ/kg (E5). The adapted experimental for 10 d experiment period lasted 60 d. Dry matter intake feed conversion ratio linearly (P < 0.001) increased decreased 0.001), respectively,...
Antibiotics are commonly overused to reduce weaning stress that leads economic loss in swine production. As potential substitutes of antibiotics, plant extracts have attracted the attention researchers. However, one extracts, tannic acid (TA), has an adverse effect on growth performance, palatability, and intestinal absorption piglets when used at a large amount. Thus, this study aimed investigate effects proper dose microencapsulated TA organ development, morphology, nutrient transporters,...
The present study was conducted to evaluate the effect of dietary folic acid on growth performance, intestinal morphology, and epithelial cells renewal in post-weaning piglets. Twenty-eight piglets (weaned at day 21, initial body weight 6.73 ± 0.62 kg) were randomly allotted 4 treatments with 7 pens per diet 1 piglet pen. fed same antibiotic-free zinc oxide-free basal diets supplemented 0, 3, 9, 18 mg/kg for 14 days. results showed that supplementation increased villus height (VH) (P =...
Background It remains unclear about the pathogenesis of intracranial aneurysms (IAs) in setting autoimmune disorders (ADs). However, underlying systemic inflammatory characteristics ADs may affect IAs through shared pathways. Therefore, this study was conducted to explore relationship between and assess causal effects. Methods In study, 6 common were included their with IAs. Besides, a bidirectional two-sample univariable Mendelian randomization (UVMR) analysis performed. addition, primary...
Abstract Weaning stresses often induce markedly structural and functional changes in the small intestine. However, little data are available on of morphology, function, health cecum piglets post-weaning. This study was conducted to measure effects weaning piglets. Forty were weaned at 21 d samples collected different time points (days 0, 1, 3, 7, 14) The crypt depth, width, total epithelial cell numbers increased days 7 14, compared with 3 (P &lt; 0.001). value Ki67/total cells highest...
The pathogenesis of pulmonary arterial hypertension (PAH) and associated biomarkers remain to be studied. Copper metabolism is an emerging metabolic research direction in many diseases, but its role PAH still unclear.PAH-related datasets were downloaded from the Gene Expression Omnibus database, 2067 copper metabolism-related genes (CMGs) obtained GeneCards database. Differential expression analysis Venn algorithm used acquire differentially expressed CMGs (DE-CMGs). DE-CMGs then for...
This study explored the effects of different protein and energy levels on growth performance serum biochemical indices ewes during early mid-pregnancy. A total 132 were assigned to 5 groups (P1, P2 = E2, P3, E1, E3) dietary (P1: 9.22%, P2: 10.04%, P3: 10.86%) (E1: 9.04 MJ/kg, E2: 9.53 E3: 10.02 MJ/kg). Blood urea nitrogen (BUN) increased with an increase in pregnancy (P .008). In group, creatinine, triglyceride, lactate lowest highest mid-pregnancy < .05). Final weight, weight gain, average...
Increased tissue redox state may result in sub-optimal growth. Our goal was to determine if glutathione (GSH) content and expression of proteins involved with GSH metabolism change longissimus dorsi (LD), subcutaneous adipose (SA), liver tissues growing vs. finishing steer phenotypes. Tissues were taken from 16 Angus steers (BW = 209 ± 29.4 kg) randomly assigned (n 8) develop through Growing (final BW 301 7.06 Finished 576 36.9 growth phases, at slaughter had achieved different rib-eye area...
Abstract Background Although salt plays an important role in maintaining the normal physiological metabolism of human body, many abnormalities liver caused by a high-salt diet, especially with pathological results, are not well characterized. Methods Eight-week-old female C57BL/6 mice were randomly divided into group and high group. These groups then fed or sodium-rich chow (containing 6% NaCl) for 6 weeks. Liver injury was evaluated, influences diet on analyzed transcriptome sequencing at...
Copper (Cu) is an essential micronutrient for animals. Many studies have been conducted on the effects of dietary Cu growth performance, intestinal morphology, and function piglets. However, underlying mechanism remains to be explored. Intestinal stem cells (ISC) drive development constant renewal epithelium. Therefore, we hypothesized that affects piglets’ via modulating ISC activity. A total eighty-five 21-day-old piglets were randomly assigned five groups, where 25, 50, 75, 100, 125 mg...
This study explored the effects of different vitamin B5 (VB5) levels on intestinal growth and function weaned piglets. Twenty-one piglets (7.20 ± 1.11 kg) were included in a 28-day feeding trial with three treatments, including 0 mg/kg (L-VB5), 10 (Control) 50 (H-VB5) VB5 supplement. The results showed that: Large intestine weight/body weight was highest H-VB5 group, Control groups had significantly higher villus height height/crypt depth than L-VB5 ileum (p < .05). Goblet cells (ileal...
Abstract This study was conducted to determine the effects of oral administration with glutamate on metabolism suckling piglets based 1 H‐Nuclear magnetic resonance ( H NMR) spectroscopy through level metabolism. Forty‐eight healthy [(Yorkshire × Landrace) Duroc] born same day a similar birth bodyweight (1.55 ± 0.20 kg) were obtained from six sows (8 per sow). The each sow randomly assigned into four treatments (2 treatment). given 0.09 g/kg body weight (BW) sodium chloride (CN group), 0.03...
Niacin deficiency leads to inflammation of mucous membranes and diarrhoea. There are few reports on the effects niacin intestinal health weaned piglets. The present study was conducted analyse in piglets along with its underlying mechanism. A total 48 25-day-old (24 females 24 males) were randomly allotted into four groups, each treatment supplemented 22.5, 30, 45, 75 mg kg-1 for a period 14 days, 12 per diet 1 piglet pen. Six (3 males 3 females) selected from group euthanised tissue...
The purpose of this study was to investigate the effects different protein levels in late pregnancy on ewe and lamb growth performance, serum biochemical indexes. Thirty-three ewes (46.4 ± 1.38 kg initial weight) were randomly divided into 3 groups, with 11 each group. three diets formulated provide components meet 10.00 MJ/kg ME requirements were: 10.12%, 11.26%, 12.4%. Ewes raised from 90th day end delivery, lambs weaned at 60 days. Dietary had significant blood urea nitrogen, glucose,...
Hepatic glutamate uptake and conversion to glutamine is critical for whole-body N metabolism, but how this process regulated during growth poorly described. The hepatic activities, protein content of system $${\text{X}}^{ - }_{\text{AG}}$$ transporters (EAAC1, GLT-1) regulatory proteins (GTRAP3-18, ARL6IP1), synthetase (GS) activity content, glutathione (GSH) were compared in liver tissue weaned Angus steers randomly assigned (n = 8) predominantly lean (growing) or lipid (finished) regimens....
Abstract Background In the setting of autoimmune disorders(ADs), formation intracranial aneurysms (IA) is poorly understood, and underlying systemic inflammatory characteristics ADs may affect IA through shared pathways. Our research sought to determine likelihood that contributed calculate magnitude causal effects. Methods We included 6 common explore their relationship with IA. performed a bidirectional two-sample univariable Mendelian randomization (UVMR) analysis. The inverse variance...
Ampelopsis megalophylla has been found to demonstrate anticancer activities in human cancer cells; however, the effect of total flavone extract (TFE), commonly used Traditional Chinese Medicine, remains unclear. Furthermore, there is limited information on its effects breast cell lines. The present study aimed investigate inhibitory TFE different In addition, underlying mechanisms and signaling pathways involved were also investigated by determining tumor morphological changes, differences...