A5087492193- Plant-Microbe Interactions and Immunity
- Fungal and yeast genetics research
- Fungal Biology and Applications
- Plant Pathogens and Fungal Diseases
- Autophagy in Disease and Therapy
- Plant Stress Responses and Tolerance
- Plant Gene Expression Analysis
- Legume Nitrogen Fixing Symbiosis
- Cellular transport and secretion
- Plant Pathogenic Bacteria Studies
- Plant Parasitism and Resistance
- Plant Disease Resistance and Genetics
- Peptidase Inhibition and Analysis
- Nematode management and characterization studies
- Plant nutrient uptake and metabolism
- Neurobiology and Insect Physiology Research
- Crystallization and Solubility Studies
- Aluminum toxicity and tolerance in plants and animals
- Mycorrhizal Fungi and Plant Interactions
- X-ray Diffraction in Crystallography
- Metal complexes synthesis and properties
- Plant biochemistry and biosynthesis
- Microbial Natural Products and Biosynthesis
- Plant tissue culture and regeneration
- Plant Pathogens and Resistance
Shandong Agricultural University
2020-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Huazhong Agricultural University
2025
Nanjing Agricultural University
2015-2024
Soochow University
2024
Hunan University of Science and Engineering
2023
Nanjing Forestry University
2021
Ministry of Education of the People's Republic of China
2019
Capital Medical University
2009
By 2050, the world population will increase to 10 billion which urged global demand for food production double. Plant disease and land drought make situation more dire, safer environment-friendly materials are thus considered as a new countermeasure. The rice blast fungus, Magnaporthe oryzae, causes one of most destructive diseases cultivated worldwide that seriously threatens production. Unfortunately, traditional breeding nor chemical approaches along control it well. Nowadays,...
Eukaryotic cells respond to environmental stimuli when cell surface receptors are bound by ligands. The binding initiates a signal transduction cascade that results in the appropriate intracellular responses. Studies have shown endocytosis is critical for receptor internalization and signaling activation. In rice blast fungus Magnaporthe oryzae, non-canonical G-protein coupled receptor, Pth11, membrane sensors MoMsb2 MoSho1 thought function upstream of G-protein/cAMP Pmk1 MAPK pathway...
Cells are faced with various stresses during their growth and development, autophagy is a degradative process in which cells can break down own components to recycle macromolecules provide energy under these stresses. For pathogenic fungi that utilize cell wall as the first barrier against external stress, integrity (CWI) pathway also provides an essential role responding However, specific connection between CWI remains elusive either model including budding yeast Saccharomyces cerevisiae or...
Macroautophagy/autophagy is critical for normal appressorium formation and pathogenicity of the rice blast fungus Magnaporthe oryzae, but molecular base autophagy linked to remains elusive in this or other pathogenic fungi. We found that MoHat1, a histone acetyltransferase (HAT) homolog, had role regulation through acetylation related proteins MoAtg3 MoAtg9. also MoHat1 was subject by protein kinase MoGsk1 modulated translocation from nucleus cytoplasm with assistance MoSsb1, chaperone. The...
Ensuring the safety of crop production presents a significant challenge to humanity. Pesticides and fertilizers are commonly used eliminate external interference provide nutrients, enabling crops sustain growth defense. However, addition chemical substances does not meet environmental standards required for agricultural production. Recently, natural sources such as biostimulants have been found help plants with The development provides new solutions product has become widely utilized tool in...
In the rice blast fungus Magnaporthe oryzae, high-affinity cyclic adenosine monophosphate (cAMP) phosphodiesterase MoPdeH is important not only for cAMP signalling and pathogenicity, but also cell wall integrity (CWI) maintenance through an unknown mechanism. By utilizing affinity purification, we found that interacts with MoMck1, one of components mitogen-activated protein (MAP) kinase cascade regulates CWI. Overexpression MoMCK1 suppressed defects in autolysis pathogenicity ΔMopdeH mutant,...
Environmental conditions are key factors in the progression of plant disease epidemics. Light affects outbreak diseases, but underlying molecular mechanisms not well understood. Here, we report that light-harvesting complex II protein, LHCB5, from rice is subject to light-induced phosphorylation during infection by blast fungus Magnaporthe oryzae We demonstrate single-nucleotide polymorphisms (SNPs) LHCB5 promoter control expression which turn correlates with LHCB5. enhances broad-spectrum...
The production of reactive oxygen species (ROS) is a ubiquitous defense response in plants. Adapted pathogens evolved mechanisms to counteract the deleterious effects host-derived ROS and promote infection. How plant regulate this elaborate against burst remains unclear. Using rice blast fungus Magnaporthe oryzae, we uncovered self-balancing circuit controlling planta virulence. During infection, induces phosphorylation high osmolarity glycerol pathway kinase MoOsm1 its nuclear...
Bacterial leaf streak caused by Xanthomonas oryzae pv. oryzicola (Xoc) is a continuous threat to rice cultivation, leading substantial yield losses with socioeconomic implications. Iron ions are essential mineral nutrients for plant growth, but little information available on how they influence mechanisms of immunity against Xoc. Here, we investigated the role myeloblastosis-related (MYB) transcriptional repressor OsMYBxoc1 in modulation resistance through control iron ion transport....
Summary We have shown previously that the transcription factor MoAP1 governs oxidative response and is important for pathogenicity in rice blast fungus Magnaporthe oryzae . To explore underlying mechanism, we identified thioredoxin MoTrx2 as a target of M. Thioredoxins are highly conserved 12‐kDa oxidoreductase enzymes containing dithiol–disulfide active site, function antioxidants against free radicals, such reactive oxygen species (ROS). In yeast fungi, thioredoxins stress tolerance...
The fungal cell wall plays an essential role in maintaining morphology, transmitting external signals, controlling growth, and even virulence. Relaxation irreversible stretching of the are prerequisites division development, but they also inevitably cause stress. Both Mitotic Exit Network (MEN) Cell Wall Integrity (CWI) signaling pathways that govern stress response, respectively, how these cross talk to coordinate cellular pathogenicity remains not fully understood. We have identified...
GTP-binding protein (G-protein) and regulator of G-protein signaling (RGS) mediated signal transduction are critical in the growth virulence rice blast pathogen Magnaporthe oryzae. We have previously reported that there eight RGS RGS-like proteins named MoRgs1 to MoRgs8 playing distinct shared regulatory functions M. oryzae has a more prominent role compared others fungus. To further explore unique mechanism MoRgs1, we screened cDNA library for genes encoding MoRgs1-interacting identified...
Rice sheath blight (ShB) caused by Rhizoctonia solani is one of the most destructive diseases in rice. Fungicides are widely used to control ShB agriculture. However, decades excessive traditional fungicide use have led environmental pollution and increased pathogen resistance. Generally, plant elicitors regarded as environmentally friendly biological pesticides that enhance disease resistance triggering immunity. Previously, we identified immune inducer ZhiNengCong (ZNC), a crude extract...
Fruit lycopene, shape, and resistance are essential traits in vegetables whose final product is fruit, they also closely related to strictly regulated by multiple transcription factors. Lycopene, which cannot be synthesized the human body can only ingested from outside, was important maintaining health. During fruit ripening post-harvest, tomato plants face a variety of biotic or abiotic stresses, might inflict great damage quality due its flat shape pointed tip during storage...
Autophagy and Cell wall integrity (CWI) signaling are critical stress-responsive processes during fungal infection of host plants. In the rice blast fungus Magnaporthe oryzae , autophagy-related (ATG) proteins phosphorylate CWI kinases to regulate virulence; however, how autophagy interplays with coordinate such regulation remains unknown. Here, we have identified phosphorylation ATG protein MoAtg4 as an important process in coordination between M . The kinase MoAtg1 phosphorylates inhibit...
Chronic inflammatory and immune dysregulation are critical drivers of the development progression chronic obstructive pulmonary disease (COPD). Posttranslational modifications, such as glycosylation Immunoglobulin G (IgG), crucial in modulating systemic homeostasis. This study aims to profile plasma IgG glycopeptides (IgGPs) COPD patients uncover new insights into their pathogenesis identify novel biomarkers. An integrated platform that combines Fe3O4@PDA@DETA nanospheres enrichment with...