A5070530148- Thyroid Disorders and Treatments
- Adipose Tissue and Metabolism
- Thyroid Cancer Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Growth Hormone and Insulin-like Growth Factors
- Mitochondrial Function and Pathology
- Muscle Physiology and Disorders
- Obstructive Sleep Apnea Research
- Cancer, Hypoxia, and Metabolism
- Biomarkers in Disease Mechanisms
- Peroxisome Proliferator-Activated Receptors
- Vitamin D Research Studies
- Exercise and Physiological Responses
- Birth, Development, and Health
- Eicosanoids and Hypertension Pharmacology
- GDF15 and Related Biomarkers
- ATP Synthase and ATPases Research
- Human Health and Disease
- Glaucoma and retinal disorders
- Regulation of Appetite and Obesity
- Digestive system and related health
- Cardiovascular Function and Risk Factors
- Congenital heart defects research
- Studies on Chitinases and Chitosanases
- Neuroscience of respiration and sleep
Poznan University of Medical Sciences
2016-2024
Introduction: Irisin, a cleaved and secreted part of the transmembrane protein FNDC5, is recently discovered adipo-myokine that said to have significant influence on body metabolism. Changes in thyrometabolic state may also alter serum irisin level. Since already reported data are not fully consistent, aim present research evaluate time-dependent changes level patients affected by overt hypothyroidism. Material methods: The study involved 36 subjects — two groups 12 with long-lasting (AITD)...
Summary Background Irisin is a new adipo‐myokine, encoded by the FNDC 5 gene. Currently, there discussion regarding relation between thyroid function and irisin concentration. This prospective study assesses influence of thyrometabolic changes on serum concentration in association with altered muscle metabolism. performed large cohort patients affected severe hypo‐ or hyperthyroidism, as well expression gene tissue different pathologies. Methods The group comprised 119 newly diagnosed...
We hypothesized that regulation of visfatin in hypothyroidism might be altered by coexisting chronic autoimmune thyroiditis. This is a prospective case-control study 118 subjects. The group (AIT) consisted 39 patients newly diagnosed with course nonautoimmune (TT) 40 thyroidectomized due to the differentiated thyroid cancer staged pT1. control comprised healthy volunteers adjusted for age, sex, and BMI normal function negative antibodies. Exclusion criteria other diseases, active neoplastic...
Subclinical hyperthyroidism (sHT) was found to be associated with elevated heart rate, blood pressure and increased risk of extrasystoles. However, the full clinical relevance morphological functional implications sHT on cardiovascular system is still a matter debate. The aim study prospectively assess influence endogenous exercise capacity cardiac function during workout use electrocardiography (ExECG) perfusion scintigraphy. studied group consisted 44 consecutively recruited patients...
To investigate the role of NAMPT/visfatin in euthyroid patients with Graves' disease without (GD) and ophthalmopathy (GO), we analyzed NAMPT leukocyte expression its serum concentration. This was a single-center, cross-sectional study consecutive enrollment. In total, 149 diagnosed were enrolled study. We excluded subjects hyper- or hypothyroidism, diabetes mellitus, other autoimmune disorders, active neoplastic disease, infection. The control group recruited among healthy volunteers...
Thyroid hemiagenesis (THA) is a rare abnormality characterized by the absence of one thyroid lobe. Elevated stimulating hormone (TSH) level and higher incidence diseases were reported in THA. The aim study to evaluate autoimmunity patients with THA influence than average TSH on volume (TV) its change age. included group naive control subjects bilobate thyroid. All underwent clinical examination, ultrasound, scintiscan laboratory tests. In studied presence autoantibodies (TAb) was evaluated....
Dysregulation of thyroid function has known impact on body metabolism, however, data regarding metabolic outcome after restoration is limited. Therefore, the aim study was to investigate effect euthyroidism serum visfatin, and its associations with insulin resistance composition. This an observational consecutive enrollment. Forty-nine hyperthyroid (median age 34 years) 44 hypothyroid women 46 completed study. Laboratory parameters composition analysis were assessed before therapy. In group,...
Abstract We aimed to analyze the potential influence of thyroid autoimmunity on visfatin/NAMPT serum concentration and its leukocyte expression in hyperthyroid patients. This is a single-center, cross-sectional study with consecutive enrollment. All patients newly diagnosed overt hyperthyroidism course Graves' disease or toxic nodular goiter were included study. They underwent physical examination, laboratory investigation, body composition analysis, ultrasound. NAMPT mRNA expressions...
It is well established that thyroid hormones significantly affect skeletal muscle function, causing symptoms like myalgia and weakness. Hypothyroid patients present increased levels of creatine kinase (CK), indicating destruction. Lately, we proposed new serum markers disturbances in disorders: titin (TTN) dystrophin (DMD). The aim this study to determine the association between status, metabolism, TTN DMD affected by hypoand hyperthyroidism, before after treatment.In 56 subjects were...
Cardiovascular diseases constitute a major cause of health problems and death in developed countries across the world. The increased value index distribution red blood cells volume (RDW) may be prognostic marker patients diagnosed with chronic heart failure (CHF). Hypothyroid present higher RDW values if compared to healthy controls. Taking into consideration that might both affected by thyroid status CHF, we decided determine effect concomitant hypothyroidism following radioiodine therapy...
The goal of this paper was the evaluation changes in expression profile irisin, ghrelin, and titin carcinoma tissue blood patients with head neck squamous cell (HNSCC), including determining their relation to patient nutrition. study included 56 diagnosed HNSCC T3 T4 stages disease. Healthy control specimens were collected from an area 10 mm outside histologically negative margin. In turn, serum group came healthy volunteers treated for non-oncologic reasons (n = 70). molecular analysis...
INTRODUCTIONThere is growing evidence that obstructive sleep apnea (OSA) influences both bone metabolism and structure.Chitinase -3-like protein 1 (YKL -40) a novel inflammatory remodeling marker, the levels of which were shown to increase in OSA.YKL -40 can probably alter turnover.OBJECTIVES The aim study was assess possible interplay between YKL turnover markers patients with different stages OSA, evaluate relation mass, severity levels. PATIENTS AND METHODSThe involved 72 male OSA.They...
ATPase inhibitory factor 1 is a myokine inhibiting the hydrolytic activity of mitochondrial adenosine triphosphate synthase and ecto-F1-ATPase on surface many cells. IF1 affects ATP metabolism in mitochondria extracellular space upregulates glucose uptake myocytes; these processes are essential physical activity. It unknown whether serum concentration associated with exercise capacity. This study explored association between resting capacity indices healthy people. was measured samples...
Abstract There is growing evidence that obstructive sleep apnoea (OSA) influences the hypothalamic–pituitary–gonadal axis (HPG axis) in men. The aim of study was to assess association nesfatin-1 with HPG disturbances OSA. This a prospective consecutive enrolment. It comprises 72 newly diagnosed OSA patients ((AHI: apnoea-hypopnea index) 18 subjects: 5 ≤ AHI < 15; 24: 15 30; 30: ≥ 30) and control group composed 19 (AHI 5). All underwent polysomnography fasting blood collection for...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Objectives: Thyroid hemiagenesis (THA) is a congenital anomaly of unknown origin. The aim this study was to assess for the first time whether there any seasonality in date birth patients with THA comparison general population. Methods: studied group consisted 105 THA. control data regarding total live births Poland were derived from Polish Statistical Annals (n = 2 421 384). Both groups subdivided according month birth, season and quarter year. Results: Analysis months revealed that born...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)