A5050255050- Pituitary Gland Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Obstructive Sleep Apnea Research
- Neuroendocrine Tumor Research Advances
- Parathyroid Disorders and Treatments
- Adrenal and Paraganglionic Tumors
- Medical Imaging and Pathology Studies
- Thyroid Disorders and Treatments
- Neuroscience of respiration and sleep
- Cancer, Hypoxia, and Metabolism
- Regulation of Appetite and Obesity
- Radiopharmaceutical Chemistry and Applications
- Thyroid and Parathyroid Surgery
- Growth Hormone and Insulin-like Growth Factors
- Hormonal Regulation and Hypertension
- Lung Cancer Research Studies
- Glioma Diagnosis and Treatment
- Bone health and treatments
- Biomarkers in Disease Mechanisms
- Adrenal Hormones and Disorders
- Diet and metabolism studies
- PARP inhibition in cancer therapy
- Genetic Syndromes and Imprinting
- Inflammation biomarkers and pathways
- Pericarditis and Cardiac Tamponade
Poznan University of Medical Sciences
2016-2024
GTx (United States)
2019
The biological association between chronic lymphocytic thyroiditis (CLT) and differentiated thyroid cancer (DTC) has not been elucidated yet. aim of the study was to assess whether presence CLT exerts any influence on clinical or histological presentation DTC. Nine hundred seven consecutive patients with DTC treated in years 1998–2016 were divided into two groups according absence concomitant CLT. statistical differences analysed. Out 907 included study, 331 diagnosed (studied group), while...
Diagnostic imaging and radionuclide therapy of prostate (PC) breast cancer (BC) using radiolabeled gastrin-releasing peptide receptor (GRPR)-antagonists represents a promising approach. We herein propose the GRPR-antagonist based radiotracer [99mTc]Tc-DB15 ([99mTc]Tc-N4-AMA-DGA-DPhe6,Sar11,LeuNHEt13]BBN(6-13); N4: 6-carboxy-1,4,8,11-tetraazaundecane, AMA: aminomethyl-aniline, DGA: diglycolic acid) as new diagnostic tool for GRPR-positive tumors applying SPECT/CT. The uptake was tested in...
Obstructive sleep apnea (OSA), a disorder characterized by repetitive collapse of the upper respiratory tract during sleep, occurs in about 4% middle-aged men and 2% women. The incidence is rising due to an increase obesity ageing population. Patients with obstructive are at elevated risk some endocrinal metabolic disorders, which may lead serious consequences including shortening life expectancy. recognition understanding interactions between local airway dysfunction its therefore vital. In...
Klotho has been recently described as a carcinogenesis suppressor. Large cell neuroendocrine lung carcinoma (LCNEC) is rare, highly malignant neoplasm. In the light of increasing incidence tumours, biomarkers predicting survival are needed. We consider that might be one.We analysed records all patients diagnosed with LCNEC, atypical carcinoid and typical operated on in our institution between 2007 2015. Initially, we found 134 cases. Forty-six specimens were unattainable thus excluded from...
Objectives The aim of this study was to investigate the fluorine-18-fluorodeoxyglucose (18F-FDG) uptake on integrated PET [PET/computed tomography (CT)] images and its correlation with nestin expression in a series neuroendocrine lung tumours. As incidence tumours is rising, tools predicting diagnosis, outcome assisting selection treatment regimens are needed. Patients methods We reviewed records patients diagnosed large cell carcinoma, atypical carcinoid typical who were operated upon our...
The study was designed to evaluate the relationship between thyroid antibodies and gland dysfunction, with aim of finding a clinically useful threshold value thyreoperoxidase antibodies, which could prove be predictive for failure.The conducted on 99 women, ages ranging from 18-91 years (mean age: 45.5 ±17.0), were treated as outpatients in Department Endocrinology, Metabolism Internal Medicine. Analysis serum samples TSH concentration anti-TPO titers conducted.The most common disorder...
INTRODUCTION Myeloid‑derived suppressor cells (MDSCs) have the potent ability to suppress T‑cell function, and are important in regulation of chronic inflammation carcinogenesis. MDSCs may influence local systemic carcinogenesis COPD; however, their presence bronchoalveolar lavage fluid (BALF) peripheral blood (PB) or relationship with clinical parameters COPD has not been studied yet. OBJECTIVES The aim study was assess BALF PB analyze between COPD. PATIENTS AND METHODS included 64 patients...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Brominska B, Gabryel P, Jarmołowska-Jurczyszyn D, et al. Clinical significance of nestin and its association with survival in neuroendocrine lung tumours. Polish Journal Pathology. 2017;68(4):291-296. doi:10.5114/pjp.2017.73924. APA Brominska, B., Gabryel, P., Jarmołowska-Jurczyszyn, D., Janicka-Jedyńska, M., Trojanowski, & Sawicka-Gutaj, N. (2017). Pathology, 68(4), 291-296....
Introduction. Ghrelin, originally isolated from the endocrine cells of gastric mucosa, is also expressed in many peripheral tissues, including normal adrenals and adrenocortical tumors. It was shown that ghrelin stimulates proliferation inhibits apoptosis cells. In current study, we compared expression at protein level various adrenal We analyzed whether immunoreactive could be considered as a potential marker for different types Material methods. Study carried out on 200 specimens arranged...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Saliva could be an attractive alternative to blood for assessing thyroid hormonal function.
INTRODUCTIONThere is growing evidence that obstructive sleep apnea (OSA) influences both bone metabolism and structure.Chitinase -3-like protein 1 (YKL -40) a novel inflammatory remodeling marker, the levels of which were shown to increase in OSA.YKL -40 can probably alter turnover.OBJECTIVES The aim study was assess possible interplay between YKL turnover markers patients with different stages OSA, evaluate relation mass, severity levels. PATIENTS AND METHODSThe involved 72 male OSA.They...
ARTICLE Ghrelin in patients with adrenocortical carcinoma 469 Histopathologic diagnosis of ACC is based on Weiss criteria. 2ACC forms a very heterogenous group tumors different biology, overall survival, and prognosis. 3The stages range from I to IV. Complete surgical resection constitutes the first essential step treatment.Mitotane single drug approved for treatment.It exerts antitumoral antihormonal effects, 4 can be beneficial both as an adjuvant therapy metastatic spread.Its effect...
BACKGROUND: Although differentiated thyroid cancer (DTC) has relatively favorable course, factors predicting the course of disease are intensively searched. The aim study was to identify clinical determining incomplete response radioiodine therapy in patients with DTC.METHODS: We retrospectively analyzed 385 consecutive DTC treated and followed-up at a single tertiary reference center. investigated detectable during first hospitalization 3-6 months following total thyroidectomy due DTC,...
The purpose of the study was to assess clinical, biochemical, and sonographic factors influencing performance parathormone washout measurement (PTHw) vs. MIBI in preoperative localization parathyroid adenoma (PA). studied group consisted 39 patients with primary or tertiary hyperparathyroidism. PTH concentrations performed using an electro-chemiluminescence immunoassay. Scintigraphic PA carried out dual-tracer planar neck scintigraphy, 74 MBq 99mTc-pertechnetate 740 99mTc-MIBI. unambiguously...
Abstract There is growing evidence that obstructive sleep apnoea (OSA) influences the hypothalamic–pituitary–gonadal axis (HPG axis) in men. The aim of study was to assess association nesfatin-1 with HPG disturbances OSA. This a prospective consecutive enrolment. It comprises 72 newly diagnosed OSA patients ((AHI: apnoea-hypopnea index) 18 subjects: 5 ≤ AHI < 15; 24: 15 30; 30: ≥ 30) and control group composed 19 (AHI 5). All underwent polysomnography fasting blood collection for...