A5018353906- Regulation of Appetite and Obesity
- Medical Imaging and Pathology Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Lung Cancer Research Studies
- Neuroendocrine Tumor Research Advances
- Neuroblastoma Research and Treatments
- Parathyroid Disorders and Treatments
- Thyroid and Parathyroid Surgery
- Adipose Tissue and Metabolism
- Folate and B Vitamins Research
- Iron Metabolism and Disorders
- Bone health and treatments
- Erythropoietin and Anemia Treatment
Poznan University of Medical Sciences
2022-2025
Despite recent advances, neuroendocrine tumors (NETs) remain a challenging topic, due to their diversity and the lack of suitable biomarkers. Multianalyte assays shift an omics-based approach improve on conventional single-analyte strategy, albeit with own drawbacks. We explored potential serum β-hCG as biomarker for NETs discussed its role in disease monitoring. recruited 40 patients non-functioning pancreatic NETs, all liver metastases. Serum concentrations were measured at 3-month...
Introduction Neuroendocrine tumors (NETs) are rare neoplasms that occur in various locations throughout the body. Despite their usually benign character, they might manifest with distant metastases. N-terminal prohormone of brain natriuretic peptide (NT-proBNP) has previously been described as a useful biomarker diagnosing carcinoid heart disease (CHD), common advanced NETs manifestation. We observed plasma concentrations NT-proBNP metastatic midgut over 4-year period. Objectives aimed to...
Hepcidin is a protein responsible for maintaining iron (Fe) homeostasis. Data regarding the role of hepcidin in pathomechanism Fe balance disturbances associated with acromegaly (AG) are scarce. The aim study was to assess impact alterations complete blood count parameters, homeostasis, gonadal status and GH/IGF-1 on level AG patients. evaluated differences concentration homeostasis between patients newly diagnosed comparison healthy control subjects (CS). We prospectively enrolled 25 adult...
Primary hyperparathyroidism is a common endocrine disorder characterised by excessive parathormone secretion that results in hypercalcemia, primarily caused parathyroid adenoma. Accurate localisation of hyperfunctioning tissue essential for curative surgical treatment. Although conventional imaging modalities like ultrasonography and
The purpose of the study was to assess clinical, biochemical, and sonographic factors influencing performance parathormone washout measurement (PTHw) vs. MIBI in preoperative localization parathyroid adenoma (PA). studied group consisted 39 patients with primary or tertiary hyperparathyroidism. PTH concentrations performed using an electro-chemiluminescence immunoassay. Scintigraphic PA carried out dual-tracer planar neck scintigraphy, 74 MBq 99mTc-pertechnetate 740 99mTc-MIBI. unambiguously...