Paweł Komarnicki

ORCID: 0000-0001-6548-0613
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About
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Research Areas
  • Neuroblastoma Research and Treatments
  • Lung Cancer Research Studies
  • Neuroendocrine Tumor Research Advances
  • Pituitary Gland Disorders and Treatments
  • Thyroid Cancer Diagnosis and Treatment
  • Adrenal and Paraganglionic Tumors
  • Infectious Encephalopathies and Encephalitis
  • Selenium in Biological Systems
  • Long-Term Effects of COVID-19
  • Hormonal Regulation and Hypertension
  • Trace Elements in Health
  • Heavy Metal Exposure and Toxicity
  • Herpesvirus Infections and Treatments
  • Parathyroid Disorders and Treatments
  • Medical Imaging and Pathology Studies
  • Hypothalamic control of reproductive hormones
  • Glioma Diagnosis and Treatment
  • Myasthenia Gravis and Thymoma
  • Radiomics and Machine Learning in Medical Imaging
  • Electrolyte and hormonal disorders

Poznan University of Medical Sciences
2021-2025

Differentiated thyroid cancer (DTC) is the most common endocrine malignancy, with incidence rising in recent decades. Despite a favorable prognosis, management remains complex, often involving thyroidectomy followed by radioactive iodine (RAI) therapy, varying efficacy. We aimed to assess predictive models for RAI therapy efficacy patients DTC and identify biomarker cutoff values. This retrospective study included 744 who underwent remnant ablation at single center. Clinicopathological...

10.20452/pamw.16920 article EN Polskie Archiwum Medycyny Wewnętrznej 2025-01-07

Introduction Certain trace elements are essential for life and affect immune system function, their intake varies by region population. Alterations in serum Se, Zn Cu have been associated with COVID-19 mortality risk. We tested the hypothesis that a disease-specific decline occurs correlates risk different countries Europe. Methods Serum samples from 551 patients (including 87 non-survivors) who had participated observational studies Europe (Belgium, France, Germany, Ireland, Italy, Poland)...

10.3389/fimmu.2022.1022673 article EN cc-by Frontiers in Immunology 2022-11-28

Introduction Neuroendocrine tumors (NETs) are rare neoplasms that occur in various locations throughout the body. Despite their usually benign character, they might manifest with distant metastases. N-terminal prohormone of brain natriuretic peptide (NT-proBNP) has previously been described as a useful biomarker diagnosing carcinoid heart disease (CHD), common advanced NETs manifestation. We observed plasma concentrations NT-proBNP metastatic midgut over 4-year period. Objectives aimed to...

10.1530/ec-23-0249 article EN cc-by-nc-nd Endocrine Connections 2023-08-08

Endogenous Cushing's Syndrome (ECS) results from excessive glucocorticoid secretion.ACTH-secreting pituitary adenomas are the most common presentation, followed by ectopic

10.20452/pamw.16748 article EN Polskie Archiwum Medycyny Wewnętrznej 2024-05-13

Despite recent advances, neuroendocrine tumors (NETs) remain a challenging topic, due to their diversity and the lack of suitable biomarkers. Multianalyte assays shift an omics-based approach improve on conventional single-analyte strategy, albeit with own drawbacks. We explored potential serum β-hCG as biomarker for NETs discussed its role in disease monitoring. recruited 40 patients non-functioning pancreatic NETs, all liver metastases. Serum concentrations were measured at 3-month...

10.3390/cancers16112060 article EN Cancers 2024-05-29

Hyperthyroidism is characterized by the increased production of thyroid hormones, with diverse etiology and treatment methods [1].The most common cause Graves' disease,

10.20452/pamw.16802 article EN Polskie Archiwum Medycyny Wewnętrznej 2024-07-12

The biochemical diagnosis of neuroendocrine tumours (NETs) uses assays specific and nonspecific markers. Nonspecific markers include, among others, neuron-specific enolase (NSE). aim this study was to evaluate NSE in patients with midgut type treated somatostatin analogues.The group NETs the small intestine included 41 patients. Grade G1 found 19 cases, while G2 seen remaining 22 cases. Liver metastases were all studied. examined analogues receiving octreotide LAR at a dose 30 mg. control...

10.5603/ep.a2021.0060 article EN cc-by-nc-nd Endokrynologia Polska 2021-07-22

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)

10.1530/endoabs.99.ep552 article EN Endocrine Abstracts 2024-05-06

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)

10.1530/endoabs.102.41 article EN Endocrine Abstracts 2024-08-30

Introduction and Objectives: Isolated hypogonadotropic hypogonadism (IHH) may be associated with pituitary gland olfactory system disorders. We aimed to correlate findings of Magnetic Resonance Imaging (MRI) the in IHH patients patients’ phenotype. Patients methods: The present research was a single-center retrospective case-control study. MRI patterns were studied 46 patients, whom 29 (63%) classified on basis olfactometry as having Kallmann syndrome (KS) (16 anosmia; 13 hyposmia) 17 (37%)...

10.1530/ec-24-0437 article EN cc-by-nc-nd Endocrine Connections 2024-12-01
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