A5071619062- Mosquito-borne diseases and control
- Long-Term Effects of COVID-19
- Inflammasome and immune disorders
- Fatty Acid Research and Health
- COVID-19 Clinical Research Studies
- Healthcare Regulation
- Patient Safety and Medication Errors
- Viral Infections and Vectors
- Science and Education Research
- IL-33, ST2, and ILC Pathways
- Public Health in Brazil
- Olfactory and Sensory Function Studies
- Virology and Viral Diseases
- COVID-19 and Mental Health
- Venous Thromboembolism Diagnosis and Management
- Adipose Tissue and Metabolism
- Gut microbiota and health
- Advancements in Transdermal Drug Delivery
- Lipid metabolism and disorders
- Photodynamic Therapy Research Studies
- Thermoregulation and physiological responses
- Neuroinflammation and Neurodegeneration Mechanisms
- Lipid Membrane Structure and Behavior
- Circadian rhythm and melatonin
- Adipokines, Inflammation, and Metabolic Diseases
Universidade de Brasília
2018-2022
The implication of inflammation in pathophysiology several type cancers has been under intense investigation. Omega-3 fatty acids can modulate and present anticancer effects, promoting cancer cell death. Pyroptosis is an related death so far, the function docosahexaenoic acid (DHA) pyroptosis not described. This study investigated role DHA triggering activation breast cells. MDA-MB-231 cells were supplemented with was analyzed. DHA-treated triggered increased caspase-1and gasdermin D...
Foam cells are specialized lipid-loaded macrophages derived from monocytes and a key pathological feature of atherosclerotic lesions. Lysophosphatidylcholine (LPC) is major lipid component the plasma membrane with broad spectrum proinflammatory activities plays role in atherosclerosis. However, LPC droplet (LD) biogenesis modulation inflammasome activation still poorly understood. In present study, we investigated whether can induce foam cell formation through an analysis LD determined...
Photodynamic therapy (PDT) mediated by photosensitizers loaded in nanostructures as solid lipid nanoparticles has been pinpointed an effective and safe treatment against different skin cancers. Amazon butters have interesting composition when it comes to forming (SLN). In the present report, a new third-generation photosensitizing system consisting of aluminum-phthalocyanine associated with butter-based (SLN-AlPc) is described. The SLN was developed using murumuru butter, monodisperse...
Abstract Zika virus (ZIKV) has a strong tropism for the nervous system and been related to post-infection neurological syndromes. Once neuronal cells are infected, is capable of modulating cell metabolism, leading neurotoxicity cellular death. The negative effect ZIKV in neuron characterized. However, description molecules reversing these cytotoxic effects still under investigation. In this context, it largely demonstrated that docosahexaenoic acid (DHA), an omega-3 polyunsaturated fatty...
Gut microbiota composition can modulate neuroendocrine function, inflammation, and cellular immunological responses against different pathogens, including viruses. Zika virus (ZIKV) infect adult immunocompetent individuals trigger brain damage antiviral responses. However, it is not known whether ZIKV infection could impact the gut microbiome from mice. Here, we investigated modifications induced by in of C57BL/6J Adult mice were infected with was analyzed next-generation sequencing V4...