A5062151567- Ethics in Clinical Research
- Patient-Provider Communication in Healthcare
- Childhood Cancer Survivors' Quality of Life
- Delphi Technique in Research
- Ethics and Legal Issues in Pediatric Healthcare
- Health Systems, Economic Evaluations, Quality of Life
- Palliative Care and End-of-Life Issues
- Mental Health and Patient Involvement
- Health Policy Implementation Science
- Pharmaceutical studies and practices
- Empathy and Medical Education
- Adolescent and Pediatric Healthcare
- Family Support in Illness
- Meta-analysis and systematic reviews
- Child and Adolescent Health
- Health and Medical Research Impacts
- Pharmacovigilance and Adverse Drug Reactions
- Autoimmune and Inflammatory Disorders Research
- Family and Disability Support Research
- Ethics in medical practice
- Clinical practice guidelines implementation
- Family and Patient Care in Intensive Care Units
- Cancer survivorship and care
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Child and Adolescent Psychosocial and Emotional Development
University of Liverpool
2016-2025
Douglas Mental Health University Institute
2025
Royal North Shore Hospital
1995-2024
Fox Corporation (United States)
2024
University of Miami
2023
Health and Human Development (2HD) Research Network
2019
RELX Group (United States)
2019
Institute of Population and Public Health
2019
John Hunter Hospital
1993-2018
Czech Academy of Sciences, Institute of Psychology
2018
Systematic review has developed as a specific methodology for searching for, appraising and synthesizing findings of primary studies, rapidly become cornerstone the evidence-based practice policy movement. Qualitative research traditionally been excluded from systematic reviews, much effort is now being invested in resolving daunting methodological epistemological challenges associated with trying to move towards more inclusive forms review. We describe our experiences, very diverse...
Objective: Qualitative research is increasingly valued as part of the evidence for policy and practice, but how it should be appraised contested. Various appraisal methods, including checklists other structured approaches, have been proposed rarely evaluated. We aimed to compare three methods appraising qualitative papers that were candidates inclusion in a systematic review on support breast-feeding. Method: A sample 12 breast-feeding was by six reviewers using methods: unprompted...
Atypical meningiomas are an intermediate grade brain tumour with a recurrence rate of 39–58 %. It is not known whether early adjuvant radiotherapy reduces the risk and potential side-effects justified. An alternative management strategy to perform active monitoring magnetic resonance imaging (MRI) treat at recurrence. There no randomised controlled trials comparing these two approaches. A total 190 patients will be recruited from neurosurgical/neuro-oncology centres across United Kingdom,...
<h3>Abstract</h3> <b>Objectives:</b> To examine young people9s and parents9 accounts of communication about cancer in childhood. <b>Design:</b> Semistructured interviews analysed using the constant comparative method. <b>Setting:</b> Paediatric oncology unit. <b>Participants:</b> 13 families, comprising 19 parents (13 mothers, six fathers) patients aged 8–17 years, recruited from one paediatric The had or brain tumour. <b>Results:</b> Most described acting an executive-like capacity,...
Qualitative research makes an important contribution to our understanding of health and healthcare. However, qualitative evidence can be difficult search for identify, the effectiveness different types strategies is unknown. Three in example area support breast-feeding were evaluated using six electronic bibliographic databases. The based on thesaurus terms, free-text terms broad-based terms. These combined with recognised previously used a Cochrane review. For each strategy, we recall...
Questionnaires were distributed to 346 fourth-year students in nine medical schools. The asked state their selected specialty and rank the importance that each of 25 influences, listed as questionnaire items, had making choice specialty. Factor analysis showed particular items significantly associated with factors. first factor emphasized perceived lifestyle (items this category gave remuneration, personal time, prestige); second cerebral activities a practice orientation; third stressed...
Funders of research are increasingly requiring researchers to involve patients and the public in their research. Patient involvement (PPI) can potentially help make sure that design is relevant, it participant friendly ethically sound. Using sharing PPI resources benefit those involved undertaking PPI, but existing not used consistently this lead duplication effort. This paper describes how we developing a toolkit support clinical trials teams unit. The will provide key 'off shelf' resource...
Core outcome sets (COS) help to minimise bias in trials and facilitate evidence synthesis. Delphi surveys are increasingly being used as part of a wider process reach consensus about what outcomes should be included COS. Qualitative research can inform the development surveys. This is an advance field COS one which potentially valuable; however, little guidance exists for developers on how best use qualitative methods challenges are. paper aims provide early potential role contribution this...
Background Patient and public involvement (PPI) is advocated in clinical trials yet evidence on how to optimise its impact limited. We explored researchers' PPI contributors' accounts of the within factors likely influence impact. Methods Semi-structured qualitative interviews with researchers contributors accessed through a cohort randomised trials. Analysis transcripts audio-recorded was informed by principles constant comparative method, elements content analysis informant triangulation....
: Patient and public involvement (PPI) in research is increasingly required, although evidence to inform its implementation limited.Inform the base by describing how plans for PPI were implemented within clinical trials identifying challenges lessons learnt teams.We compared extracted from trial grant applications (funded National Institute Health Research Technology Assessment Programme between 2006 2010) with researchers' contributors' interview accounts of implementation. Analysis...
Objective Alternatives to prospective informed consent enable children with life-threatening conditions be entered into trials of emergency treatments are needed. Across Europe, a process called deferred has been developed as an alternative. Little is known about the views and experiences those first-hand experience this controversial process. To inform how sought for future paediatric critical care trials, we explored parents practitioners involved in CATheter infections CHildren (CATCH)...
While non-operative treatment has emerged as an alternative to surgery for the of uncomplicated acute appendicitis in children, comparative patient-centred outcomes are not well documented. We investigated these a feasibility randomised trial. Of 57 participants, data were available 26. Compared with appendicectomy, children allocated reported higher short-term quality life scores, shorter duration requiring analgesia, more rapid return normal activities and parental absence from work. These...