A5101874037- Dialysis and Renal Disease Management
- Renal Transplantation Outcomes and Treatments
- Organ Donation and Transplantation
- Organ Transplantation Techniques and Outcomes
- Renal and Vascular Pathologies
- Central Venous Catheters and Hemodialysis
- Chronic Kidney Disease and Diabetes
- Health Systems, Economic Evaluations, Quality of Life
- Pregnancy and Medication Impact
- Renal Diseases and Glomerulopathies
- Neurological Complications and Syndromes
- Pregnancy and preeclampsia studies
- Healthcare Policy and Management
- Healthcare cost, quality, practices
- Legal principles and applications
- Viral-associated cancers and disorders
- Archaeology and Natural History
- Diabetes Treatment and Management
- Acute Kidney Injury Research
- Transplantation: Methods and Outcomes
- Commonwealth, Australian Politics and Federalism
- Judicial and Constitutional Studies
- Muscle and Compartmental Disorders
- Climate Change and Health Impacts
- Indigenous Health, Education, and Rights
The University of Adelaide
2016-2025
Australia and New Zealand Dialysis and Transplant Registry
2016-2025
South Australian Health and Medical Research Institute
2016-2025
Royal Adelaide Hospital
2016-2025
Medical Research Institute of New Zealand
2024
Women's and Children's Health Network
2017-2024
James Cook University
2024
The University of Texas Southwestern Medical Center
2023
Central Adelaide Local Health Network
2017-2023
SA Health
2013-2022
Immune suppression after organ transplantation is associated with a markedly increased risk of nonmelanoma skin cancer and few virus-associated cancers. Although it generally accepted that other cancers do not occur at rates, there have been long-term population-based cohort studies performed.To compare the incidence in patients receiving immune kidney same population 2 periods before receipt suppression: during dialysis end-stage disease renal replacement therapy (RRT).A study 28,855 who...
Although renal-replacement therapy for children with end-stage renal disease has been used several decades, data on patients' long-term survival are sparse.
ABSTRACT. The native arteriovenous fistula (AVF) is the preferred vascular access because of its longevity and lower rates infection intervention. Recent studies suggest that AVF may offer a survival advantage. Because these data were derived from observational studies, they are prone to potential bias. use propensity scores offers an additional method reduce bias resulting nonrandomized treatment assignment. Adult (age 18 yr or more) patients who commenced hemodialysis in Australia New...
Mortality differences between peritoneal dialysis (PD) and hemodialysis (HD) are widely debated. In this study, mortality was compared patients treated with PD HD (including home HD) using data from 27,015 in the Australia New Zealand Dialysis Transplant Registry, 25,287 of whom were still receiving or 90 d after entry into registry. Overall rates significantly lower during 90- to 365-d period among those being at day (adjusted hazard ratio [HR] 0.89; 95% confidence interval [CI] 0.81 0.99];...
Peritonitis is a major complication of peritoneal dialysis, but the relationship between peritonitis and mortality among these patients not well understood. In this case-crossover study, we included 1316 who received dialysis in Australia New Zealand from May 2004 through December 2009 either died on or within 30 days transfer to hemodialysis. Each patient served as his her own control. The mean age was 70 years, time receiving 3 years. total, there were 1446 reported episodes with 27%...
Cardiovascular (CVS) disease is the commonest cause of death after kidney transplantation. In general population, CVS mortality has reduced significantly over last two decades; however, this trend not been specifically examined in transplant population.We studied all patients Australia and New Zealand with a functioning between 1980 2007 trends timing 2195 deaths recorded transplantation Dialysis Transplant registry. Poisson regression was used to compare rates time periods.CVS events were...
We analyzed data from the Australia and New Zealand Dialysis Transplant Registry for 1 October 2003 to 31 December 2008 with aim of describing nature peritonitis, therapies, outcomes in patients on peritoneal dialysis (PD) Australia. At least episode PD was observed 6639 patients. The overall peritonitis rate 0.60 episodes per patient–year (95% confidence interval: 0.59 0.62 episodes), 6229 occurring 3136 Of those episodes, 13% were culture-negative, 11% polymicrobial. Gram-positive...
Background. After transplantation, cancer risk varies from no increase for several common cancers to a many-fold number of, chiefly virus-associated, cancers. The smaller excess of in dialysis has been less well described, but two studies suggested that impaired immunity might be responsible.
SUMMARY Background: Renal replacement therapy (RRT) consumes sizable proportions of health budgets internationally, but there is considerable variability in choice RRT modality among and within countries with major implications for outcomes costs. We aimed to quantify these increasing kidney transplantation improving the rate home‐based dialysis. Methods: A multiple cohort Markov model was used assess costs new end‐stage disease (ESKD) patients Australia 2005–2010, using a health‐care funder...
Although obesity is associated with increased risks of morbidity and death in the general population, a number studies patients undergoing hemodialysis have demonstrated that increasing body mass index (BMI) correlated decreased mortality risk. Whether this association holds true among treated peritoneal dialysis (PD) has been less well studied. The aim investigation was to examine between BMI outcomes new PD large cohort, long-term follow-up monitoring. Using data from Australia New Zealand...
Backgound. While obesity increases postoperative complications and cardiovascular risks, its effects on long-term kidney transplant outcomes are less clear. Methods. We used data from the Australian New Zealand Dialysis Transplant (ANZDATA) Registry to examine relationships between body mass index (BMI, classified according World Health Organization criteria) at outcome. Patients starting renal replacement therapy April 1991 who received a single-organ, primary (when aged ≥16 years) December...
Although early studies observed that peritoneal membrane transport characteristics were determinants of morbidity and mortality in dialysis (PD) patients, more recent investigations, such as the Ademex trial, have refuted these findings. The aim this study was to determine whether baseline status predicted subsequent survival Australian New Zealand PD patients. included all adult patients Australia who commenced between April 1, 1999, March 31, 2004, had a equilibration test (PET) performed...
<b>Objective</b> To compare cancer incidence in kidney transplant recipients during periods of function (and immunosuppression) and after failure (when immunosuppression is ceased or reduced). <b>Design, setting, participants</b> Nationwide, population based retrospective cohort study 8173 Australian registered on the Australia New Zealand Dialysis Transplant Registry who first received a 1982-2003. Incident cancers were ascertained using linkage with national registry records. <b>Main...
Understanding the impact of hepatitis C virus (HCV) infection in patients with end-stage renal disease before and after transplantation requires more data. We examined outcomes HCV antibody positive (HCVAb+) dialysis transplant using Australian New Zealand Dialysis Transplant registry.Two cohorts (n=23,046) (n=7572) were identified. Survival outcomes, causes mortality, graft failure examined.Dialysis Cohort: 362 (1.6%) HCVAb+ve. The cause HCVAb+ve group was likely to be glomerulonephritis or...
Fertility rates, pregnancy, and maternal outcomes are not well described among women with a functioning kidney transplant. Using data from the Australian New Zealand Dialysis Transplant Registry, we analyzed 40 yr of pregnancy-related for transplant recipients. This analysis included 444 live births reported 577 pregnancies; absolute but relative fertility rate fell during these four decades. Of pregnancies achieved, 97% were beyond first year after transplantation. The mean age at time...
Summary Background and objectives Pregnancy in ESRD is rare poses substantial risk for mother baby. This study describes a large series of pregnancies women undergoing long-term dialysis treatment reviews maternal fetal outcomes. Specifically, who had conceived before after starting are compared. Design, setting, participants, & measurement All reported to the Australian New Zealand Dialysis Transplantation Registry from 2001 2011 ( n =77), following introduction specific parenthood data...
Extremely high temperatures over many consecutive days have been linked to an increase in renal disease several cities. This is becoming increasingly relevant with heatwaves longer, more intense, and frequent climate change. study aimed extend the known relationship between daily temperature kidney include incidence of eight temperature-prone specific categories – total disease, urolithiasis, failure, acute injury (AKI), chronic (CKD), urinary tract infections (UTIs), lower (LUTIs)...