A5084832466- Ethnobotanical and Medicinal Plants Studies
- Pharmacological Effects of Natural Compounds
- Ziziphus Jujuba Studies and Applications
- Natural Antidiabetic Agents Studies
- Drug-Induced Hepatotoxicity and Protection
- Natural product bioactivities and synthesis
- Essential Oils and Antimicrobial Activity
- Traditional and Medicinal Uses of Annonaceae
- Phytochemistry and Biological Activities
- Phytochemistry and biological activities of Ficus species
- Morinda citrifolia extract uses
- Pharmacogenetics and Drug Metabolism
- Phytochemistry and Bioactivity Studies
- Phytochemicals and Medicinal Plants
- Alkaloids: synthesis and pharmacology
- Phytochemistry and biological activity of medicinal plants
- Neuroscience and Neuropharmacology Research
- Phytochemistry and Bioactive Compounds
- Bioactive Compounds and Antitumor Agents
- Vaccine Coverage and Hesitancy
- Malaria Research and Control
- Medicinal Plants and Neuroprotection
- Moringa oleifera research and applications
- Advances in Cucurbitaceae Research
- Computational Drug Discovery Methods
National Institute for Pharmaceutical Research and Development
2012-2023
Adamawa State University
2020
Universidade Federal de Mato Grosso
2015-2017
Mbarara University of Science and Technology
2014
Kampala International University
2008-2011
Ahmadu Bello University
2008-2009
Vernonia amygdalina possesses several bioactive compounds and is used in traditional medicines of southwestern Uganda, along with other regions. Its analgesic potential has not been investigated thus far. The present study examines the antinociceptive aqueous leaf extract (50–200 mg/kg) using three models nociception (acetic acid-induced writhing, formalin test, tail-flick test), antiplasmodial activity, toxicology extract. results show significantly inhibits acetic writhing test mice but...
Zizyphus spina-christi (Rhamnaceae) grows wild in tropical Africa and Asia can be domesticated. It has folkloric usage pain related ailments throughout these regions. In view of the claimed therapeutic potentials, investigation plant’s root bark was initiated our laboratory. The plant material first sequentially extracted with hexane, chloroform, ethylacetate methanol, this report, a fraction (numbered) ZS-4D from methanol extract eluted 70:30% (chloroform : methanol) using flash column...
Abstract A methanol extract of Zizyphus oxyphylla Edgew leaves has been investigated for its analgesic and antipyretic activities in Adult Wistar Swiss albino mice either sex at 50, 100 200 mg/kg orally. The demonstrated marked activity against Brewer's yeast‐induced pyrexia rats. significant peripheral effect the acetic acid‐induced writhing test mice. phytochemical tests revealed that contained alkaloids, anthraquinones, flavonoids, glycosides, phenols, resins, saponins tannins using...
Copaifera malmei Harms (Fabaceae) is a plant that occurs in the central region of Brazil, where plant's leaves infusion popularly used to treat gastric ulcer and inflammatory diseases. This study was aimed investigate gastroprotective activity mode action plants' order establish scientific basis for such usage, assess its potential as source an anti-ulcer agent. Leaves extract (SIECm) prepared, freeze dried lyophilised. Its qualitative quantitative phytochemical constituents were...
ABSTRACT Preclinical Research Ocimum gratissimum L. leaves have attracted considerable attention from researchers because of their medicinal value that include anti‐inflammatory, analgesic, antimicrobial, and antioxidant activities. In the present study, toxicity protective effect phenolic extract O. leaf (EAFO g ) against acute inflammation oxidative stress in rats was assessed. EAFOg, enriched phenols had no cytotoxic CHO‐k1 cells, lethality brine shrimp eggs or mice at a dose 2000 mg/kg....
Abstract Background: Ocimum gratissimum leaf is used in managing rheumatism and other inflammatory conditions. In this study, we investigated the antioxidant anti-inflammatory effects of phenolic extract obtained by sequential methanol extraction O. leaves (MEO g ). Methods: The ) was after maceration (n-hexane, chloroform methanol) dried leaves. fingerprint using a high-performance liquid chromatrographic method. vitro were tested 1,1-Diphenyl-2-picryl-hydrazyl (DPPH), nitric oxide (NO)...
Preparations of Crossopteryx febrifuga have been used in traditional medicine for treatment pain and malaria many years their efficacies are widely acclaimed among the Hausa communities northern Nigeria. The methanolic extract C. was evaluated analgesic, anti-inflammatory, antipyretic anti-plasmodial activities rodents. significantly diminished acetic acidinduced writhes mice increased threshold rats dose-dependently. It also demonstrated significant anti-plasmodial, anti-inflammatory a...
Copaifera malmei Harms (Fabaceae), known mainly as óleo-mirim, is a native and endemic plant found in the states of Mato Grosso Goiás Brazil. The plant's leaves infusion popularly used by riverine communities northern Araguaia microregion, Grosso, Brazil, for treatment gastric ulcers inflammatory diseases respiratory tract. antiulcer activity standardized extract (SIECm) rodents has been reported. objective this study was to advance investigation safety profile SIECm evaluating genotoxicity...
Zizyphus spina-christi is used in ethnomedical practice for the treatment of fever. Bio-assay guided investigation plant's root bark was initiated and ZS-2A, a fraction from chloroform extract material, eluted with hexane-ethylacetate (50:50) using flash column chromatography, evaluated vivo antiplasmodial activity against Plasmodium berghei mice. Four-day suppressive, curative effect established infection prophylactic models studies were used. The (25, 50 100 mg/kg, p.o.) showed potent...