Yige Zhang

ORCID: 0000-0001-6213-1899
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About
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Research Areas
  • Bone Metabolism and Diseases
  • Osteoarthritis Treatment and Mechanisms
  • Diabetic Foot Ulcer Assessment and Management
  • Renal Diseases and Glomerulopathies
  • Listeria monocytogenes in Food Safety
  • Inflammasome and immune disorders
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Immune Response and Inflammation
  • Foot and Ankle Surgery
  • Extracellular vesicles in disease
  • Bacterial biofilms and quorum sensing
  • Nanoplatforms for cancer theranostics
  • Cancer-related molecular mechanisms research
  • Blood groups and transfusion
  • Menopause: Health Impacts and Treatments
  • Complement system in diseases
  • Bacterial Infections and Vaccines
  • Pressure Ulcer Prevention and Management
  • Cardiovascular Function and Risk Factors
  • Rheumatoid Arthritis Research and Therapies
  • Cytokine Signaling Pathways and Interactions
  • Catalytic Processes in Materials Science
  • Metal-Organic Frameworks: Synthesis and Applications
  • Heme Oxygenase-1 and Carbon Monoxide
  • Wound Healing and Treatments

The University of Tokyo
2025

The First People's Hospital of Changzhou
2020-2024

Soochow University
2017-2024

Wenzhou Medical University
2023-2024

First Affiliated Hospital of Zhengzhou University
2017-2024

State Key Laboratory of Biotherapy
2018-2022

Sichuan University
2018-2022

Henan Normal University
2018

Listeria monocytogenes is an important food-borne pathogen that can persist in food processing environments and thus contaminate products. Benzalkonium chloride (BC) a common disinfectant widely used industry. Selective pressure associated with exposure to BC may result adaptation this agent L. monocytogenes. In study, the effect of on susceptibility antimicrobial agents tolerance environmental stresses, as well role efflux pumps were investigated Exposure progressively increasing...

10.3389/fmicb.2018.02906 article EN cc-by Frontiers in Microbiology 2018-11-28

Summary Complement activation has a deep pathogenic influence in immunoglobulin (Ig)A nephropathy (IgAN). C3a and C5a, small cleavage fragments generated by complement activation, are key mediators of inflammation. The exert broad proinflammatory effects binding to specific receptors (C3aR C5aR, respectively). However, no studies thus far have investigated the C3a, C5a their on IgAN. We observed that C3aR C5aR antagonists repressed IgA-induced cell proliferation interleukin (IL)-6 monocyte...

10.1111/cei.12961 article EN Clinical & Experimental Immunology 2017-03-15

Acute ischemic stroke (AIS) induces high level of neutrophils, which correlates inversely with patient survival. Pyroptosis induced by gasdermin D (GSDMD) has been shown to have an important role in the pathophysiology several inflammatory disorders. The GSDMD neutrophils after AIS is unknown. Using a middle cerebral artery occlusion (MCAO) mouse model, we identified activation pyroptosis signal, including expression caspase-1/11, GSDMD, and interleukin-1β/18 (IL-1β/18), brain spleen at...

10.1038/s41420-023-01349-6 article EN cc-by Cell Death Discovery 2023-02-08

Background: Immune cells play a pivotal role in maintaining ovarian function. However, the specific contributions of different immune cell phenotypes to pathogenesis ovarian-related diseases remain poorly understood. We aim investigate correlation between 731 immunophenotypes and diseases. Materials Methods: Utilizing publicly available genetic data, we undertook series quality control measures identify instrumental variables (IVs) associated with exposure. Subsequently, conducted two-sample...

10.1097/js9.0000000000001814 article EN cc-by-nc-nd International Journal of Surgery 2024-06-17

Abstract Desulfurization technology is rather difficult and urgently needed for carbon dioxide (CO 2 ) utilization in industry. A new Cu(I)‐based adsorbent was synthesized examined the capacity of removing carbonyl sulfide (COS) from a CO stream an effort to solve competitive adsorption between COS seek opportunity advance capacity. wide range characterization techniques were used investigate physicochemical properties Cu(I) featuring π ‐complexation their correlations with performance....

10.1002/smo.20240027 article EN cc-by Smart Molecules 2025-01-04

To investigate whether angiogenesis changes in early menopausal osteoporosis treated with estrogen replacement therapy, 120 rats were randomly divided into five groups: sham operation group (SHAM), ovariectomy (OVX), and plus three different doses therapy groups (OVX + E2). We detected the bone microarchitecture measured expression levels of receptor beta (ER β ), vascular endothelial growth factor (VEGF), osteoprotegerin (OPG), activator NF- κ B ligand (RANKL). CD31 immunofluorescence...

10.1155/2019/1283717 article EN BioMed Research International 2019-07-04

To explore the bidirectional causal relationship between Ankylosing Spondylitis (AS) and Osteoarthritis (OA) at genetic level within European ancestry. We implemented a series of quality control steps to select instrumental variables (IVs) related exposure. conducted two-sample Mendelian randomization (MR) using inverse-variance weighted method as primary approach. adjusted significance levels Bonferroni correction, assessed heterogeneity Cochrane's Q test. Sensitivity analysis was through...

10.3389/fimmu.2024.1297454 article EN cc-by Frontiers in Immunology 2024-02-06

Aim: Atrial cardiomyopathy (ACM) is characterized by atrial dysfunction. This study aims to assess the prognostic significance of ACM in patients with noncardioembolic stroke (NCS).

10.5551/jat.64756 article EN Journal of Atherosclerosis and Thrombosis 2024-04-18

The surgical treatment and management of postoperative soft tissue complications in diabetic patients with displaced calcaneal fractures are still controversial. We aimed to evaluate the short-term efficacy percutaneous minimally invasive screw fixation Sanders II III under subtalar arthroscopy assisted by preoperative musculoskeletal ultrasonic locating lateral branch (LCB) sural nerve calcaneal-talar joint distraction device. clinical data 52 diagnosed or from March 2016 August 2020 were...

10.1186/s12891-024-07960-7 article EN cc-by-nc-nd BMC Musculoskeletal Disorders 2024-10-25

Background: Genetic factors are considered important risk for the occurrence of osteoarthritis (OA), which has received extensive attention. This study examined research on relationship between genetic and pathogenesis OA from a bibliometric perspective. Methods: We searched Web Science Core Collection original review articles OA. used R package “bibliometrix” to perform statistical visualization analysis countries, institutions, authors, journals, keywords. Results: A...

10.20944/preprints202312.1346.v1 preprint EN 2023-12-18
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