Di Lu

ORCID: 0009-0002-5499-260X
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About
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Research Areas
  • Advancements in Battery Materials
  • Advanced Battery Materials and Technologies
  • Supercapacitor Materials and Fabrication
  • Cancer-related molecular mechanisms research
  • Ferroptosis and cancer prognosis
  • RNA modifications and cancer
  • Animal Behavior and Reproduction
  • Healthcare and Venom Research
  • Mesenchymal stem cell research
  • Epigenetics and DNA Methylation
  • Amphibian and Reptile Biology
  • Esophageal Cancer Research and Treatment
  • Spinal Fractures and Fixation Techniques
  • Spine and Intervertebral Disc Pathology
  • Metabolomics and Mass Spectrometry Studies
  • interferon and immune responses
  • Histone Deacetylase Inhibitors Research
  • Advanced Algorithms and Applications
  • Advanced Sensor and Control Systems
  • Geoscience and Mining Technology
  • Lung Cancer Treatments and Mutations
  • Physical Activity and Health
  • Biochemical and biochemical processes
  • Scoliosis diagnosis and treatment
  • Genomics and Chromatin Dynamics

Capital Medical University
2023-2025

Guangzhou Medical University
2025

Atatürk University
2025

Third Affiliated Hospital of Sun Yat-sen University
2021-2024

Sun Yat-sen University
2021-2024

Van Andel Institute
2022-2024

Tongde Hospital of Zhejiang Province
2023-2024

Center for Life Sciences
2024

Tsinghua University
2024

Peking University
2024

Abstract The purpose of this study was to investigate the in vivo bone response strontium‐containing hydroxyapatite (Sr‐HA) bioactive cement injected into cancellous bone. Sr‐HA iliac crest rabbits for 1, 3, and 6 months. Active formation remodeling were observed after 1 month. Newly formed grow onto 3 Thick osteoid layer with osteoblasts along guided over surface reflected stimulating effect Sr‐HA. From scanning electron microscopy (SEM) energy‐dispersive X‐ray (EDX) analysis, high calcium...

10.1002/jbm.a.20089 article EN Journal of Biomedical Materials Research Part A 2003-12-30

Environmental variation associated with season length is likely to promote differentiation in life-history traits, but has been little studied natural populations of ectotherms. We investigated patterns egg size, clutch age at sexual maturity, maximum age, mean growth rate and adult body size relation among 17 Andrew’s toad (Bufo andrewsi) different latitudes altitudes the Hengduan Mountains, western China. found that increased decreasing season, whereas showed a converse cline. Body did not...

10.1186/s12983-016-0138-0 article EN cc-by Frontiers in Zoology 2016-02-09

Studies in genetically 'identical' individuals indicate that as much 50% of complex trait variation cannot be traced to genetics or the environment. The mechanisms generate this 'unexplained' phenotypic (UPV) remain largely unknown. Here, we identify neuronatin (NNAT) a conserved factor buffers against UPV. We find Nnat deficiency isogenic mice triggers emergence bi-stable polyphenism, where littermates emerge into adulthood either 'normal' 'overgrown'. Mechanistically, is mediated by an...

10.1038/s42255-022-00629-2 article EN cc-by Nature Metabolism 2022-09-12

Tibial cortex transverse distraction is a surgical method for treating severe diabetic foot ulcers (DFUs), but the underlying mechanism unclear. We show that antioxidant proteins and small extracellular vesicles (sEVs) with multiple-tissue regenerative potential are released during bone transport (BT) in humans rats. These accumulate wounds enriched microRNAs (miRNAs) (e.g., miR-494-3p) have high activities improve circulation of ischemic lower limbs while also promoting neovascularization,...

10.1016/j.xcrm.2024.101588 article EN cc-by-nc-nd Cell Reports Medicine 2024-05-22

Hypothalamic hamartomas (HHs) are congenital developmental malformations located in the hypothalamus. They associated with a characteristic clinical manifestation known as gelastic seizures (GS). However, traditional understanding of HHs has been limited, resulting insufficient treatment options and high recurrence rates after surgery. This is consistent network hypothesis focal epilepsy that epileptogenic zone not only limited to HH but may also involve distant cerebral cortex external...

10.1177/11795735241237627 article EN cc-by-nc Journal of Central Nervous System Disease 2024-03-05

Background: Immune cells play a pivotal role in maintaining ovarian function. However, the specific contributions of different immune cell phenotypes to pathogenesis ovarian-related diseases remain poorly understood. We aim investigate correlation between 731 immunophenotypes and diseases. Materials Methods: Utilizing publicly available genetic data, we undertook series quality control measures identify instrumental variables (IVs) associated with exposure. Subsequently, conducted two-sample...

10.1097/js9.0000000000001814 article EN cc-by-nc-nd International Journal of Surgery 2024-06-17

As the foundation of Web3 trust system, blockchain technology faces increasing demands for scalability. Sharding emerges as a promising solution, but it struggles to handle highly concurrent cross-shard transactions (\textsf{CSTx}s), primarily due simultaneous ledger operations on same account. Hyperledger Fabric, permissioned blockchain, employs multi-version concurrency control parallel processing. Existing solutions use channels and intermediaries achieve cross-sharding in Fabric....

10.48550/arxiv.2501.04265 preprint EN arXiv (Cornell University) 2025-01-07

Digital technology is reshaping the landscape of higher education, especially in field computer science. As digital platforms become central to learning process, understanding student engagement these continuously evolving environments increasingly vital. This study explores current state online among undergraduate science students, investigates factors influencing their engagement, and proposes strategies enhance education. The research framework grounded TPACK model, behaviorist theory,...

10.1038/s41598-025-90142-9 article EN cc-by-nc-nd Scientific Reports 2025-02-26

Objective: To evaluate the efficacy and safety of stereotactic electroencephalography (SEEG)-guided 3D radiofrequency thermocoagulation (RF-TC) in treatment drug-resistant mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE-HS). Methods: This study was a randomized controlled trial. The patients mTLE-HS recruited from Xuanwu Hospital, Capital Medical University between August 2019 October 2022 were prospectively enrolled. randomly assigned to receive either anterior lobectomy...

10.3760/cma.j.cn112137-20240925-02179 article EN PubMed 2025-03-18

Recent studies of humans, dogs and rodents have started to discover the genetic underpinnings high altitude adaptations, yet amphibians received little attention in this respect. To identify possible signatures adaptation altitude, we performed a genome scan 15 557 single nucleotide polymorphisms (SNPs) obtained with restriction site-associated DNA sequencing pooled samples from 11 populations Andrew's toad (Bufo andrewsi) edge Tibetan Plateau, spanning an altitudinal gradient 1690 2768...

10.1111/mec.13722 article EN Molecular Ecology 2016-06-11

Premature senescence is related to progerin and involves in endothelial dysfunction liver diseases. Activating sirtuin 1 (SIRT1) ameliorates fibrosis. However, the mechanisms of premature defenestration hepatic sinusoidal cells (HSECs) how SIRT1 affects HSECs fenestrae remain elusive.

10.1111/cpr.12991 article EN Cell Proliferation 2021-02-01

Prospective clinical-radiographic study.To investigate the natural coupling behavior between frontal deformity correction and simultaneous changes in thoracic kyphosis, to examine how postoperative sagittal realignment relates this behavior.Restoration of alignment is one fundamental goals scoliosis surgery. It generally achieved by rod precontouring intraoperatively. However, clinical studies suggested that seems be more affected inherent properties spine rather than instrumentation or...

10.1097/brs.0b013e3181bb49f3 article EN Spine 2010-03-25

Fifty sets of photographs showing facial features Caucasian males aged 18 to 60 years were examined establish a morphological classification the face. It is suggested that such could assist identification by photocomparison. The selection criteria stress importance interassessor agreement and discrimination among feature subset units in formulating proposed classification.

10.1520/jfs13998j article EN Journal of Forensic Sciences 1996-09-01

In Brief Study Design. A prospective study on comparing coronal deformity correction in thoracic scoliosis using four different instrumentations. Objectives. To compare the ability of instrumentation systems correcting based curve flexibility as reviewed by fulcrum-bending radiograph. Summary Background Data. The radiograph has been shown to be able accurately reflect curves, and fulcrum bending index (FBCI) predicts amount achieved current surgical techniques. By recruiting curves known...

10.1097/01.brs.0000106494.14707.b2 article EN Spine 2004-02-24

Three new leucothane-type (1–3), two micrathane-type (4, 5), eight grayanane-type diterpenoids (6–13), and four known compounds were obtained from the ethanol extract of leaves twigs Rhododendron decorum. The structures determined based on NMR spectra, quantum chemical calculations, X-ray crystallography. antinociceptive activities 1, 3, 4, 6, 8, 10–13, 15–17 evaluated via acetic acid-induced writhing test. Compounds 11–13, 15 exhibited significant activities. In particular, 12 found to be...

10.1021/acs.jnatprod.7b00941 article EN Journal of Natural Products 2018-05-14

SnSe possesses great potential as an engaging anode candidate for lithium-ion batteries (LIBs) due to its excellent lithium storage capabilities. Nonetheless, the poor electrical conductivity and large volume expansion upon cycling greatly limit practical application. Rational design synthesis of material with outstanding electrochemical performance are highly desirable. Herein, a one-dimensional hollow tubular structured SnSe@NCNT nanomaterial nanoparticles encapsulated in carbon nanotubes...

10.1021/acssuschemeng.3c05884 article EN ACS Sustainable Chemistry & Engineering 2023-12-22
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