A5050626716- Immune Cell Function and Interaction
- Complement system in diseases
- Diabetes and associated disorders
- Hemoglobinopathies and Related Disorders
- Hepatitis C virus research
- HIV Research and Treatment
- Head and Neck Cancer Studies
- Lymphoma Diagnosis and Treatment
- HIV-related health complications and treatments
- Monoclonal and Polyclonal Antibodies Research
- Prostate Cancer Diagnosis and Treatment
- Effects of Radiation Exposure
- HIV/AIDS drug development and treatment
- Hepatitis B Virus Studies
- Parasites and Host Interactions
- Amoebic Infections and Treatments
- Liver Disease Diagnosis and Treatment
- Atherosclerosis and Cardiovascular Diseases
- Chronic Lymphocytic Leukemia Research
- Antimicrobial Peptides and Activities
- Service-Oriented Architecture and Web Services
- Semantic Web and Ontologies
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Invertebrate Immune Response Mechanisms
- Immunodeficiency and Autoimmune Disorders
Universidade de Pernambuco
2011-2024
Universidade de Brasília
2024
Military Institute of Engineering
2014-2024
Universidade Federal do Piauí
2023
Universidade Federal de Pernambuco
2014-2017
Federico II University Hospital
1997-1998
New York Medical College
1991
Lectins are carbohydrate-binding proteins broadly distributed in plants and have several biological functions, including antimicrobial action. Portulaca elatior is a Caatinga plant whose chemical composition biotechnological potential not been extensively studied. In this work, lectin was isolated from P. root extract evaluated for activity. The (PeRoL) showed native molecular mass of 33 kDa, pI 3.8 comprised two subunits 15 kDa linked by disulfide bonds. No sequence similarities with...
O objetivo no presente artigo foi o de relatar um caso clínico insucesso do tratamento primário e retratamento endodôntico realizado em única sessão. Paciente 42 anos, encaminhado ao consultório especialista endodontia para molar inferior. exame radiográfico demonstrou uma obturação adequada. material obturador removido com sistema rotatório Prodesgn repreparo Lima Solla Collors rotatórias 50/04 a patência foraminal feita Glidepath 16/02 forame apical.. A realizada pela técnica cone único...
Trata-se de um relato caso com objetivo descrever o tratamento endodôntico do primeiro molar superior direito canal mésio-vestibular 2 (MV2). Paciente gênero masculino, 54 anos idade, compareceu a consultório particular e após anamnese exame clínico recebeu diagnóstico pulpite irreversível. O foi realizado em sessão única, iniciando pela anestesia, isolamento absoluto cirurgia acesso, localização todos os canais inserto ultrassom The finder (Helse, Brasil), preparo químico-mecânico sistema...
Objetivo: Analisar a inter-relação entre as práticas de harmonização orofacial e implantodontia através uma revisão integrativa. Métodos: Trata-se um estudo descritivo do tipo integrativa da literatura com artigos publicados 2014 2024, nos idiomas inglês e/ou português íntegra completa, selecionados das bases dados: PubMed, MEDLINE, SciELO BVS, utilizando-se os descritores: “Dental Implants”, “Esthetics” “Mouth Rehabilitation”. Resultados: Após análise criteriosa dos trabalhos científicos,...
Variations in the root canal anatomy of a maxillary first molar are often challenging to diagnose and treat; thus, clinicians must have thorough knowledge same. This case report highlights successful nonsurgical endodontic management with an unusual morphology. Three canals were prepared using Sequence Niti rotary instruments (MK Life) #25.06, irrigated 2,5% sodium hypochlorite solution. Root filling was performed single cone technique associated Bio-C Sealer cement 25.06 taper gutta-percha...
BackgroundMannose-binding lectin (MBL) activates the complement system promoting opsonophagocytosis, which could represent an advantage for Mycobacterium leprae, intracellular pathogen. Therefore, a single nucleotide polymorphism (SNP) in MBL2 gene associated with low levels of MBL confer protection against development leprosy disease.MethodsIn this study, we investigated SNPs and 228 Brazilian patients 232 controls.ResultsThere were no differences frequencies variant genotypes haplotypes...
This work reports, for the first time, purification, characterization and antibacterial activity of an elastase inhibitor from Lasiodora sp. hemocytes (EILaH). The hemocyte extract inhibited chymotrypsin (22%), trypsin (44%), tissue plasminogen activator (52%), urokinase (58%) human neutrophil (99%). EILaH was purified by Trypsin-Sepharose column RP-HPLC. SDS-PAGE revealed a molecular mass 8 kDa MALDI-TOF spectrometry single 8274 Da. amino terminal sequence determined LPC(PF)PYQQELTC....
Turner syndrome (TS) is characterized by a set of clinical conditions, including autoimmune/inflammatory diseases and infectious that can compromise patient's quality life. Here we assessed polymorphisms in CTLA-4 +49A/G (rs231775), PTPN22 +1858G/A (rs2476601), MBL2 -550 (H/L) (rs11003125), -221(X/Y) (rs7096206) exon 1 (A/O) women from northeastern Brazil to determine whether within these key immune response genes confer differential susceptibility conditions TS. A case-control genetic...
OBJETIVO: Avaliar a necessidade de monitoração semanal, pela contagem leucócitos e plaquetas, dos pacientes portadores câncer das áreas cabeça pescoço, tórax pelve submetidos radioterapia externa convencional. MATERIAIS E MÉTODOS: Cento um adultos, pescoço (11 pacientes), (35 pacientes) (55 radioterapia, avaliados semanalmente com leucograma comparando-se as contagens células antes do início tratamento obtidas nas semanas ao longo tratamento, área tratada, sexo faixa etária. RESULTADOS: A...
Interleukin 12 plays an important role in immunoregulation between the T helper 1/T 2 lymphocytes and antiviral antitumor immune response. The aim of this study was to investigate possible association interleukin 12B polymorphism rs3212227 risk develop Hodgkin's lymphoma childhood adolescents. A total 100 patients with a group 181 healthy controls were selected at random from forensic laboratory University Pernambuco. AA genotype detected (53.04%) AC found (54%). showed development (odds...
Objetivo: analisar as estratégias de cuidado Enfermagem empregadas no manejo da dor em crianças com anemia falciforme. Método: revisão integrativa literatura sobre o tema nas bases virtuais dados Scielo, Lilacs, PubMed, MEDLINE e BDENF nos meses janeiro fevereiro 2020. Resultados: foram selecionados 17 artigos identificadas duas categorias analíticas: conhecimento dos profissionais educação das familiares processo patológico tratamento farmacológico não para dor. Conclusão: como...
Infectious complications represent the main cause of morbidity and mortality in chronic lymphocytic leukemia. It has been reported that polymorphisms mannosebinding lectin 2 (MBL2) genes are correlated with MBL protein serum levels and, consequently, associated development infectious diseases.The purpose this study was to investigate possible association between MBL2 gene risk infection leukemia patients.Peripheral blood samples from 116 patients were collected; after genomic DNA extraction,...
Sickle cell anemia (SCA) presents heterogenous clinical manifestations that cannot be explained solely by alterations to hemoglobin (Hb); other components such as endothelial adhesion, thrombosis and inflammation may involved. The mannose-binding lectin (MBL) has an important role in innate immunity inflammatory diseases. In this report, we describe association between MBL2 polymorphism related low production of serum MBL the frequency vasoocclusive events (FVOE) children ≤ 5 years old with...