A5029787709- Healthcare during COVID-19 Pandemic
- Healthcare Regulation
- Education during COVID-19 pandemic
- Phytochemistry Medicinal Plant Applications
- Glycosylation and Glycoproteins Research
- Agricultural and Food Sciences
- Influenza Virus Research Studies
- Acute Lymphoblastic Leukemia research
- Histone Deacetylase Inhibitors Research
- Immunotherapy and Immune Responses
- SARS-CoV-2 and COVID-19 Research
- Rural Development and Agriculture
- Antioxidants, Aging, Portulaca oleracea
- Click Chemistry and Applications
- Plant-Microbe Interactions and Immunity
- Extracellular vesicles in disease
- Papaya Research and Applications
- Immune Cell Function and Interaction
- Peptidase Inhibition and Analysis
- Respiratory viral infections research
- Galectins and Cancer Biology
- Plant Pathogenic Bacteria Studies
- SARS-CoV-2 detection and testing
- Public Health in Brazil
Universidade Federal de Pernambuco
2016-2024
This work describes the isolation of a lectin (CasuL) from leaf pinnulae Calliandra surinamensis and evaluation its cytotoxic, antimicrobial antibiofilm properties. Proteins extract were precipitated with ammonium sulphate (60% saturation) submitted to Sephadex G-75 chromatography, which yielded isolated CasuL (purification factor: 113). Native is an acidic protein (pI 5.82) relative molecular mass 48 kDa. also oligomeric composed three subunits spectrometry revealed similarities Sorghum...
Lectins are carbohydrate-binding proteins broadly distributed in plants and have several biological functions, including antimicrobial action. Portulaca elatior is a Caatinga plant whose chemical composition biotechnological potential not been extensively studied. In this work, lectin was isolated from P. root extract evaluated for activity. The (PeRoL) showed native molecular mass of 33 kDa, pI 3.8 comprised two subunits 15 kDa linked by disulfide bonds. No sequence similarities with...
Paullinia cupana (Guarana) is a native plant of Amazon region that has very traditional importance. Its seeds are rich in bioactive compounds, including tannins, which exhibit relevant properties. Objective. This study aimed to evaluate antibacterial, antineoplastic, and immunomodulatory activity P. crude extract (CE) ethyl-acetate fraction (EAF). Methods. Antibacterial was evaluated by determination minimal inhibitory concentration (MIC) bactericidal (MBC). Antineoplastic MTT assays...
Multiple myeloma (MM) is a malignant disease characterized by the proliferation of plasma cells, primarily in bone marrow. It accounts for approximately 1% all cancers and 10% hematologic malignancies. Clinical manifestations include hypercalcemia, anemia, renal failure, lesions. The pathogenesis MM involves complex interactions between cells their microenvironment. Galectins, family β-galactoside-binding proteins, particularly galectin-1, -3, -4, -7, -9, have been implicated development....
A ampla testagem da população é uma das formas mais eficazes para o controle disseminação Covid-19. Portanto, a Universidade Federal de Pernambuco (UFPE), em parceria com outras instituições públicas, forneceu infraestrutura e prestação serviço realização dos exames moleculares do novo coronavírus, ampliando na no estado Pernambuco. Este artigo relata experiência UFPE processo implementação teste molecular detecção Para implementação, foram necessárias articulações conjuntas entre Gabinete...
Introdução: A pandemia da COVID-19 causou impacto no cenário mundial nos últimos anos, levando também a implicações para carga de trabalho dos profissionais saúde, sobretudo os equipe enfermagem. Objetivo: Descrever o perfil clínico pacientes com internados em uma UTI e Métodos: Estudo descritivo, transversal, abordagem quantitativa, mediado por análise documental. Foram analisados prontuários diagnóstico um centro terapia intensiva durante meses março 2020 fevereiro 2022. Resultados: 261...
Herein, the authors describe a simple enhancement to commercial rapid DNA extraction kit based on viral lysis for detecting COVID-19 via RT-qPCR.After testing several different modifications, adapted protocol with best results in preliminary experiments was statistically evaluated comparison an automated robotic protocol.Processing and of 119 nasopharyngeal samples ultimately yielded near-perfect agreement (κ = 0.981 [95% confidence interval 0.943-1.000]).The low cost rapidity enhanced makes...