James C. Kile

ORCID: 0000-0001-6240-2871
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About
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Research Areas
  • Animal Disease Management and Epidemiology
  • Influenza Virus Research Studies
  • Viral Infections and Vectors
  • Viral gastroenteritis research and epidemiology
  • Respiratory viral infections research
  • Zoonotic diseases and public health
  • Poxvirus research and outbreaks
  • COVID-19 epidemiological studies
  • Bacillus and Francisella bacterial research
  • Mosquito-borne diseases and control
  • Disaster Response and Management
  • Food Waste Reduction and Sustainability
  • Viral Infections and Outbreaks Research
  • Clinical Laboratory Practices and Quality Control
  • Pneumonia and Respiratory Infections
  • Human-Animal Interaction Studies
  • COVID-19 Pandemic Impacts
  • Fecal contamination and water quality
  • Herpesvirus Infections and Treatments
  • Plant and Fungal Interactions Research
  • Water Treatment and Disinfection
  • Data-Driven Disease Surveillance
  • Healthcare and Environmental Waste Management
  • Plant Virus Research Studies
  • Market Dynamics and Volatility

National Center for Immunization and Respiratory Diseases
2005-2023

Centers for Disease Control and Prevention
2005-2023

Chattogram Veterinary and Animal Sciences University
2020

Johns Hopkins University
2020

Centers for Disease Control and Prevention
2017

Ministry of Health
2015

National Institute of Public Health
2015

National Center for Health Research
2015

CDC Foundation
2015

National Center for Environmental Health
2005-2006

Effectively preventing and controlling zoonotic diseases requires a One Health approach that involves collaboration across sectors responsible for human health, animal health (both domestic wildlife), the environment, as well other partners. Here we describe Generalizable Framework (GOHF), five-step framework provides structure using in disease programs being implemented at local, sub-national, national, regional, or international level. Part of is toolkit compiles existing resources...

10.1038/s41598-022-12619-1 article EN cc-by Scientific Reports 2022-05-21

Abstract Most infectious diseases that recently emerged in humans originated animals. Besides close contact between animals and humans, other factors probably contribute to the cross-species transmission of diseases. It is critical establish effective mechanisms for coordination collaboration animal, human, environmental health sectors before new threats emerge by bringing different together tackle endemic zoonotic greatest concern. Such multisectoral partnerships should begin identifying...

10.3201/eid2313.170544 article EN cc-by Emerging infectious diseases 2017-10-31

In 2003, human monkeypox was first identified in the United States. The outbreak associated with exposure to infected prairie dogs, but potential for person-to-person transmission a concern. This study examines health care worker (HCW) 3 patients confirmed monkeypox.Exposed HCWs, defined as HCWs who entered 2-m radius surrounding case monkeypox, were by infection-control practitioners. A self-administered questionnaire and analysis of paired serum specimens determined status, immune...

10.1086/427805 article EN Clinical Infectious Diseases 2005-02-17

Among all influenza viruses assessed using CDC's Influenza Risk Assessment Tool (IRAT), the Asian lineage avian A(H7N9) virus (Asian H7N9), first reported in China March 2013,* is ranked as with highest potential pandemic risk (1). During October 1, 2016-August 7, 2017, National Health and Family Planning Commission of China; CDC, Taiwan; Hong Kong Centre for Protection; Macao CDC 759 human infections H7N9 viruses, including 281 deaths, to World Organization (WHO), making this largest five...

10.15585/mmwr.mm6635a2 article EN MMWR Morbidity and Mortality Weekly Report 2017-09-07

In Bangladesh, live bird market environments are frequently contaminated with avian influenza viruses. Shop-level biosecurity practices might increase risk for environmental contamination. We sought to determine which shop-level were associated surveyed 800 poultry shops describe and collect samples. Samples from 205 (26%) positive A viral RNA, 108 (14%) H9, 60 (8%) H5. Shops that slaughtered poultry, kept overnight, remained open without rest days, had uneven muddy floors, held on the...

10.3201/eid2609.191029 article EN cc-by Emerging infectious diseases 2020-07-23

Abstract Cross-species virus transmission events can lead to dire public health emergencies in the form of epidemics and pandemics. One example animals is emergence H3N8 equine influenza (EIV), first isolated 1963 Miami, FL, USA, after emerging among horses South America. In early 21st century, American lineage EIV diverged into two ‘Florida’ clades that persist today, while an transferred dogs around 1999 gave rise canine (CIV), reported 2004. Here, we compare CIV reveal their host-specific...

10.1093/ve/vead052 article EN cc-by-nc Virus Evolution 2023-07-01

<h3>Objective</h3> To describe a cluster of human monkeypox cases associated with exposure to ill prairie dogs in home child care. <h3>Design, Setting, Participants</h3> We identified all persons exposed 2 pet County A, Indiana; performed active surveillance for symptomatic infection; and evaluated the types that may have resulted infection. For children who attended care where animals were housed, we also measured rate seroconversion virus. <h3>Main Outcome Measures</h3> Nine (13%) 70...

10.1001/archpedi.159.11.1022 article EN Archives of Pediatrics and Adolescent Medicine 2005-11-01

Abstract Objective —To estimate West Nile virus (WNV) infection rates, assess environmental variables that correlated with seropositivity in dogs and cats, whether pets should be considered as possible sentinels for WNV therefore of potential human exposure. Design —Cross-sectional serosurvey. Animals —442 138 cats. Procedure —Serum samples were screened against by use the plaque reduction neutralization test. Results —116 (26%) 13 (9%) cats yielded positive results. The odds outdoor-only...

10.2460/javma.2005.226.1349 article EN Journal of the American Veterinary Medical Association 2005-04-01

After an outbreak of West Nile virus (WNV) infections in Slidell, Louisiana, 2002, we detected neutralizing antibodies to WNV 13 120 mammals, representing five six species sampled. Seroprevalence was measured opossum, Didelphis virginiana (75%, n = 8), raccoons, Procyon lotor (60%, 5), black rats, Rattus rattus (6%, 36), hispid cotton Sigmodon hispidus (4%, 24), and eastern gray squirrels, Sciurus carolinensis (2%, 43).

10.1089/vbz.2005.5.288 article EN Vector-Borne and Zoonotic Diseases 2005-09-01

Chlorination destroys pathogens in swimming pool water, but by-products of chlorination can cause human illness. We investigated outbreaks ocular and respiratory symptoms associated with chlorinated indoor pools at two hotels.We interviewed registered guests companions who stayed hotels X Y within 2 days outbreak onset. performed bivariate stratified analyses, calculated relative risks (RR), conducted environmental investigations areas.Of 77 hotel X, 47 (61%) completed questionnaires. Among...

10.1289/ehp.9555 article EN public-domain Environmental Health Perspectives 2006-11-28

During February 2013-March 2015, a total of 602 human cases low pathogenic avian influenza A(H7N9) were reported; no autochthonous reported outside mainland China. In contrast, since highly A(H5N1) reemerged during 2003 in China, 784 16 countries and poultry outbreaks 53 have been reported. Whether the absence China represents lack spread or detection remains unclear. We compared epidemiologic virologic features used animal surveillance data collected April 2013-May 2014 from 4 Southeast...

10.3201/eid2105.141756 article EN cc-by Emerging infectious diseases 2015-04-06

In 2003, a major power outage occurred in the midwest and northeast United States affecting some 50 million people. The outages affected multiple systems state local municipalities and, turn, public health.Semi-structured interviews were conducted using open-ended questionnaires, with convenience sample of state- locally selected subject matter experts from Ohio, Michigan, New York. Respondents interviewed groups representing one five areas interest, including: (1) emergency preparedness;...

10.1017/s1049023x00002259 article EN Prehospital and Disaster Medicine 2005-04-01

Mutation and reassortment of highly pathogenic avian influenza A(H5N1) viruses at the animal-human interface remain a major concern for emergence with pandemic potential. To understand relationship H5N1 circulating in poultry those isolated from humans, comprehensive phylogenetic molecular analyses collected both hosts Vietnam between 2003 2010 were performed. We examined temporal spatial distribution human cases relative to outbreaks characterized genetic lineages amino acid substitutions...

10.1093/infdis/jix003 article EN public-domain The Journal of Infectious Diseases 2017-01-04

We conducted environmental surveillance to detect avian influenza viruses circulating at live poultry markets (LPMs) and farms in Guangxi Autonomous Region, China, where near the China-Vietnam border. From November through April 2017-2018 2018-2019, we collected samples from 14 LPMs, 4 farms, 5 households with backyard two counties of tested for A, H5, H7, H9 by real-time reverse transcription-polymerase chain reaction (rRT-PCR). In addition, four cross-sectional questionnaire surveys among...

10.1016/j.bsheal.2022.12.006 article EN cc-by-nc-nd Biosafety and Health 2023-01-02

Highly pathogenic avian influenza (HPAI) H5N1 is endemic in Vietnamese poultry and has caused sporadic human infection Vietnam since 2003. Human infections with HPAI are of concern due to a high mortality rate the potential for emergence pandemic viruses sustained human-to-human transmission. Viruses isolated from humans southern have been classified as clade 1 single genome constellation (VN3) their earliest detection This consistent this clade/genotype Mekong River Delta surrounding...

10.1371/journal.pone.0133867 article EN public-domain PLoS ONE 2015-08-05

Please cite this paper as : Vuong et al . (2013). The genetic match between vaccine strains and circulating seasonal influenza A viruses in Vietnam, 2001–2009. Influenza Other Respiratory Viruses 7(6), 1151–1157. Background Vietnam is currently developing domestic capability to manufacture vaccines but information on the antigenic characteristics of locally limited. To assess relevance WHO recommended situation we analyzed relatedness hemagglutinin (HA) gene from 2001 2009 over same period....

10.1111/irv.12038 article EN other-oa Influenza and Other Respiratory Viruses 2012-11-08

ABSTRACT Cross-species virus transmission events can lead to dire public health emergencies in the form of epidemics and pandemics. One example animals is emergence H3N8 equine influenza (EIV), first isolated 1963 Miami, Florida, USA, after emerging among horses South America. In early 21 st century American lineage EIV diverged into two ‘Florida’ clades that persist today, while an transferred dogs around 1999 gave rise canine (CIV), reported 2004. Here, we compare CIV reveal their...

10.1101/2023.03.22.533763 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2023-03-23

<sec> <title>BACKGROUND</title> Avian influenza (AI) virus detections occurred frequently in 2022 and continue to pose a health, economic, food security risk. The most recent global analysis of official reports animal outbreaks human infections with all reportable AI viruses was published almost decade ago. Increased or renewed viruses, especially high pathogenicity H5N8 H5N1 birds H5N1, H5N8, H5N6 humans globally, have established the need for comprehensive review current surveillance data...

10.2196/preprints.46383 preprint EN 2023-02-17
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