- Viral gastroenteritis research and epidemiology
- Salmonella and Campylobacter epidemiology
- Streptococcal Infections and Treatments
- Clostridium difficile and Clostridium perfringens research
- Health Systems, Economic Evaluations, Quality of Life
- Escherichia coli research studies
- Antimicrobial Resistance in Staphylococcus
- Gut microbiota and health
- Antibiotic Resistance in Bacteria
- Nosocomial Infections in ICU
- Cervical Cancer and HPV Research
- Mycobacterium research and diagnosis
- Bacillus and Francisella bacterial research
- Antibiotic Use and Resistance
- Otolaryngology and Infectious Diseases
- Gastrointestinal motility and disorders
- Actinomycetales infections and treatment
- Statistical Methods in Clinical Trials
- Viral Infections and Outbreaks Research
- Leptospirosis research and findings
- Meta-analysis and systematic reviews
- Advanced Biosensing Techniques and Applications
- SARS-CoV-2 detection and testing
- Fecal contamination and water quality
- Pharmaceutical Practices and Patient Outcomes
Hospital Universitario Río Hortega
2000-2025
Université Paris Cité
2005
Université Paris-Saclay
2005
Clostridioides difficile infection (CDI) is currently one of the most important causes infectious diarrhea in developed countries and main cause healthcare settings. Here, we characterized gut microbiota from feces 57 patients with nosocomial community-acquired CDI. We performed an ecological analysis by high-throughput sequencing V3-V4 region 16S rRNA amplicons evaluated association various profiles CDI risk factors. Among all samples Bacteroidaceae 31.01%, Enterobacteriaceae 9.82%,...
An extensively drug-resistant (XDR) Klebsiella pneumoniae isolate MS3802 from a tracheostomy exudate was whole-genome sequenced using MiSeq and Oxford Nanopore MinION platforms in order to identify the antimicrobial resistance virulence determinates their genomic context. Isolate belonged clone ST23 presented capsular serotype K1, associated with hypervirulent K. (hvKp) isolates. The harboured chromosomally encoded blaCTX-M-15 gene contained large IncHI1B hybrid virulence/resistance plasmid...
Background Enteroaggregative Escherichia coli (EAEC) is increasingly associated with domestically acquired diarrheal episodes in high-income countries, particularly among children. However, its specific role endemic diarrhea this setting remains under-recognized and information on molecular characteristics of such EAEC strains limited. We aimed to investigate the occurrence patients non-travel related Spain molecularly characterize illness setting. Methods In a prospective multicenter study,...
Health-related quality of life (HRQL) measurements enable us to take patient perception into account when evaluating treatment outcomes from clinical trials (CTs). The purpose this study was evaluate the use HRQL questionnaires as a measurement efficacy in CT design. A duplicate systematic review CTs examined by Clinical Research Ethics Committee between 1995 and 2006 performed check for HRQL. We gathered data concerning general aspects including medical specialty, drugs evaluated,...
Clostridioides difficile infection (CDI) is the leading cause of healthcare-associated diarrhea. The associated with a high mortality rate and risk recurrence. We assessed factors for death or recurrent CDI in patients diabetes mellitus (DM).
Since the discovery of SARS-CoV-2 virus, polymerase chain reaction technique (RT-PCR) has become fundamental method for diagnosing disease in its acute phase. The objective is to describe demand-based series RT-PCR determinations received at a Microbiology Service third-level reference hospital health area three months spanning from onset epidemic by SARS-CoV-2. A retrospective analysis total requested analyzed 02/25/2020 05/26/2020 (90 days) been carried out. They have grouped...