A5042861604- Heat shock proteins research
- Ovarian cancer diagnosis and treatment
- Neuroscience and Neuropharmacology Research
- Biochemical effects in animals
- Nonmelanoma Skin Cancer Studies
- Cancer and Skin Lesions
- Sarcoma Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
- Healthcare and Venom Research
- Uterine Myomas and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Urological Disorders and Treatments
- Animal Ecology and Behavior Studies
- BRCA gene mutations in cancer
- Gastrointestinal Tumor Research and Treatment
- Epilepsy research and treatment
- Genetics and Neurodevelopmental Disorders
- Infectious Diseases and Mycology
- Nitric Oxide and Endothelin Effects
- Biliary and Gastrointestinal Fistulas
- Ear and Head Tumors
- Renal and related cancers
- COVID-19 Clinical Research Studies
- Multiple and Secondary Primary Cancers
- Pelvic and Acetabular Injuries
Medical University of Sofia
2012-2025
Ministry of Interior
2024
Medical University Plovdiv
2024
Alexandrovska Hospital
2012-2023
University of Central Florida
2018
Florida College
2018
Background: The Notch signaling pathway is an important regulator of stem cell activity in various tissues, including the central nervous system. It has been implicated neurodevelopmental processes, neuronal differentiation and synaptic plasticity. Research suggests that its expression may be associated with certain epileptogenic lesions, particularly those origin. aim this study was to investigate Notch-1 brain biopsies from cases pharmacoresistant epilepsy. Methods: Here, we used...
With the growing popularity of winter sports, it is necessary to pay more attention types traumatic injuries that a person can sustain in various incidents related their practice. We present case which an adult man died as result collision with tree while skiing. Although deaths are associated different and severity craniocerebral majority cases, here we dealing abdominal injury rupture stomach, pancreas, left renal artery. The exact localization resulting mechanism occurrence were examined....
To provide an overview of the morphologic subtypes ovarian carcinomas in Bulgaria relation to current healthcare organization using Bulgarian National Cancer Registry data. Further, we investigated hospital volume as a factor influencing quality care for patients with cancer.Bulgarian carcinoma data were retrieved (2009-2011) and distribution histologic types was analyzed. Cases divided compared respect main treatment: no surgery, surgery at hospitals dealing ≥30 cancer patients/year (high...
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal of gastrointestinal tract. Rarely, GISTs can be located in mesentery, retroperitoneal space, omentum or pancreas. In these cases, neoplasm is defined as "extra-gastrointestinal tumors" (EGISTs).We reported a case 63-year-old male patient diagnosed by computer tomography with large intraabdominal tumor vague origin, postoperatively determined an EGIST. The diagnosis was confirmed immunohistochemical study. had multiple,...
Background: αB-crystallin (HspB5) is a chaperone whose role as marker of innate immunity activation well its therapeutic potential have recently been investigated in several inflammatory diseases: multiple sclerosis, myocardial ischemia, and Guillain–Barré syndrome. Aim: The aim this study to determine the chronic obstructive pulmonary disease (COPD) pathogenesis inflammation. Materials: Plasma levels were studied 163 patients: 52 healthy non-COPD smokers; 20 COPD smokers Global Initiative...
A 67-year-old woman presented with clinical symptoms, radiological findings, and preoperative work-up highly suggestive of advanced stage IV carcinoma the gallbladder (CG). An extended cholecystectomy excision adjacent liver segments loco-regional lymphadenectomy was performed. Final pathology results revealed diffuse xanthogranulomatous cholecystitis (XG) ruptured Rokitansky-Aschoff sinuses tumor-resembling adenomyosis without atypical or malignant cells. There a reactive inflammatory fatty...
Methanol, or wood alcohol, is a clear liquid with weak odor, slightly sweeter than ethanol, which easily accessible. The last makes it product of choice for intentional self-harm, severe intoxication, even suicide. Accidental ingestion and homicidal usage are not exclusions. We present discuss the case man in his 20s who was continuous alcoholic intoxication until he finally abused methanol admitted to hospital, where died six days later. When comes there often no apparent findings that...
Summary We present a case of 75-year-old female who underwent total abdominal hysterectomy with bilateral salpingooophorectomy for an ovarian tumor. Hematoxylin-eosin- stained slides from tumor specimen revealed 1) focci benign Brenner tumor; 2) mucinous cysts and 3) intracystic papillary projections resembling low-grade transitional cell carcinoma (Grade 1-2) squamous differentiation comedo-type necrosis; 4) focal areas noninvasive Grade 3. Immunohistochemical investigation panel antibodies...
Cervical cancer is one of the most common oncologic diseases, diagnosed during pregnancy and its management significantly varies depending on stage cancer, age pregnancy, patient’s wishes. We present a case 31-year-old multiparous woman, with cervical routine monitoring at 12 weeks gestation. Due to desire keep was treated 14th gestational cold knife conization done. The successful normal delivery in 39th week. presented an example for role importance colposcopy diagnostic abnormal cytology,...