A5101447467- Head and Neck Cancer Studies
- Advanced Radiotherapy Techniques
- Ear and Head Tumors
- Brain Metastases and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Salivary Gland Tumors Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Digital Radiography and Breast Imaging
- Head and Neck Surgical Oncology
- Lung Cancer Research Studies
- Lung Cancer Diagnosis and Treatment
- Colorectal Cancer Screening and Detection
- Cardiovascular Health and Risk Factors
- Radiation Therapy and Dosimetry
- Cardiovascular Disease and Adiposity
- Pancreatitis Pathology and Treatment
- Advanced X-ray and CT Imaging
- Appendicitis Diagnosis and Management
- Statistical Methods and Inference
- Blood disorders and treatments
- Statistical Methods in Clinical Trials
- Surgical site infection prevention
- Sirtuins and Resveratrol in Medicine
- Gastric Cancer Management and Outcomes
- Testicular diseases and treatments
Sun Yat-sen University
2014-2025
Sun Yat-sen University Cancer Center
2014-2025
Key Laboratory of Guangdong Province
2023
State Key Laboratory of Oncology in South China
2014-2023
Baotou Central Hospital
2008-2022
Xinjiang Medical University
2015
Yunnan Agricultural University
2015
First Affiliated Hospital of Xinjiang Medical University
2015
Chengdu Third People's Hospital
2014
University of Southern California
2012
SIRT6, a member of the NAD (+)-dependent class III deacetylase sirtuin family, plays important roles in maintenance cardiovascular homeostasis. Telomere shortening is risk factor for age-associated diseases, including heart disease. In present study, we investigated role SIRT6 and telomerase mouse model transverse aortic constriction (TAC)-induced failure. reverse transcriptase (TERT), telomere repeat binding (TRF)-1 were significantly downregulated TAC mice compared with their expression...
This study aims to investigate the feasibility of contouring target volume according residual tumor and decreasing dose regression field after induction chemotherapy (IC) in locoregionally advanced nasopharyngeal carcinoma (NPC).From August 2009 2013, patients with stage III-IVB NPC were treated IC concurrent chemoradiotherapy. Gross nasopharynx (GTVnx)-residual gross cervical lymph node (GTVnd)-residual contoured post-IC primary any N+ disease, respectively. The was included CTVnx1/CTVnd1...
Nonalcoholic fatty liver disease (NAFLD) has become an emerging health issue with a high prevalence in general population. The cross-sectional study was performed to investigate the association between NAFLD and coronary artery calcification (CAC) individuals from northern city of China. A total 2345 participants aged ≥40 (1035 men 1310 women) were selected Jidong community Tangshan city. Liver ultrasonography used diagnosis NAFLD. 64-slice CT scanner determine score (CACS), CACS > 0 defined...
Background: The aim of this study was to build nomograms predict local recurrence (LR) and regional (RR) in patients with nasopharyngeal carcinoma (NPC) underwent intensity-modulated radiation therapy (IMRT). Patients Methods : A total 1811 non-metastatic NPC treated IMRT (with or without chemotherapy) between October 2009 February 2012 at our center were involved for building the nomograms. Nomograms LR-free rate RR-free 3- 5- year generated as visualizations Cox proportional hazards...
Abstract Past epidemiologic studies have indicated that the ideal cardiovascular health (CVH) metrics are associated with a lower risk of diseases (CVDs) and stroke. Carotid artery stenosis (CAS) causes approximately 10% ischemic strokes. The association between CVH extracranial CAS has not yet been assessed. In current study, was assessed by carotid duplex ultrasonography. Logistic regression used to analyze CAS. A total 3297 participants (52.2% women) aged 40 years older were selected from...
Early and accurate assessment of severity in acute pancreatitis (AP) is great importance to provide effective disease management prevent mortality. In this study, we aim evaluate early indicators that predict the mortality AP. We retrospectively analyzed 24-hour clinical characteristics laboratory data 166 AP patients recruited between January 2014 November 2015 Baotou Central Hospital. total, 18 did not survive disease. Multivariate logistic regression showed red cell distribution (RDW) (OR...
To validate the feasibility and efficiency of a fully automatic knowledge-based planning (KBP) method for nasopharyngeal carcinoma (NPC) cases, with special attention to possible way that success rate auto-planning can be improved. A dose volume histogram (DVH) prediction model was developed based on 99 formerly treated NPC patients, by means which optimization objectives corresponding priorities intensity modulation radiation therapy (IMRT) were automatically generated each head neck organ...
Aortic stenosis (AS) leads to chronic pressure overload, cardiac remodeling and eventually heart failure. Chemokines their receptors have been implicated in overload‑induced dysfunction. In the present study, role of C‑C chemokine receptor 5 (CCR5) dysfunction was investigated mice subjected transverse aortic constriction (TAC). Cardiac levels CCR5 motif ligands (CCLs)3, 4 were determined by western blotting reverse transcription‑quantitative PCR, respectively. functional parameters...
Surgical site infections (SSIs) are among the most common complications after definitive treatment for intestinal fistulae. Serum inflammatory markers including white blood cell count (WBC), C-reactive protein (CRP), interleukin-6 (IL-6), as well procalcitonin (PCT) have been used to help diagnosis post-operative complications.The goal of this study was assess clinical value markers, specifically IL-6, in predicting SSIs fistulae resection.A total 184 consecutive patients who underwent...
We consider the power and sample size calculation of diagnostic studies with normally distributed multiple correlated test results. derive statistics obtain formulas. The methods are illustrated using an example comparison CT PET scanner for detecting extra-hepatic disease colorectal cancer.
Abstract Background and purpose To explore whether a highly refined dose volume histograms (DVH) prediction model can improve the accuracy reliability of knowledge-based volumetric modulated arc therapy (VMAT) planning for cervical cancer. Methods materials The proposed underwent repeated refining through progressive training until samples increased from initial 25 prior plans up to 100 cases. estimated DVHs derived models different runs were compared in 35 new cancer patients analyze effect...
Abstract Background Most nasopharyngeal carcinoma (NPC) protocols define primary gross tumor volume (GTVnx) plus a range from 2 to 5 mm as the high‐dose clinical target (hd‐CTV). However, in China, hd‐CTV is defined GTVnx 0 mm. Methods A total of 40 patients with newly diagnosed nonmetastatic NPC (T1–T4 ten cases each) treated IMRT were consecutively enrolled. Real and virtual treatment plans designed according definitions recommended by China Radiation Therapy Oncology Group (RTOG),...
We assessed the diagnostic value of "one-step" dual energy CT (DECT) in combination with coronary angiography and iodine mapping within myocardial blood pool detecting acute infarction (AMI).Five minipigs were subjected to transcatheter embolization artery a gelatin sponge induce AMI. Arterial-phase DECT imaging was carried out 1 h before 24 after embolism coronary. Color-coded maps used evaluate deficits 17-segment model. Myocardial MI induction for final comparison post-mortem histology.We...
Objective To verify IMRT plans in point,planar and 3D dose,and to concretely analyze the dose differences of anatomic structure based on Gamma passing rate.Methods Thimble ion-chamber,Matrixx ArcCheck were separately used measure six nasopharyngeal carcinoma treatment lung cancer plans.The measurement deviation center point was compared as well rate verification under criteria both 3％/3 mm 2％/2 mm,the group t-test one-way ANOVA also proceeded.3DVH system target volume (TV) organ at risk...
Background To analyze the relationship between rotational and residual setup errors dose deviation on nasopharyngeal carcinoma (NPC) treated by helical tomotherapy (HT). Methods From 25 July 2017 to 20 August 2019, 16 NPC patients were enrolled in study. These scanned with full target range megavoltage computed tomography (MVCT) every other day. Adaptive radiotherapy function application software MIM7.1.3 used accumulate actual dose. The initial plan of patients’ organs at risk (OAR)...