A5046209435- Head and Neck Cancer Studies
- Lung Cancer Research Studies
- Head and Neck Surgical Oncology
- Advanced Radiotherapy Techniques
- Lung Cancer Diagnosis and Treatment
- Brain Metastases and Treatment
- Radiation Therapy and Dosimetry
- Medical Imaging Techniques and Applications
- Lung Cancer Treatments and Mutations
- Ear and Head Tumors
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Radiomics and Machine Learning in Medical Imaging
- Gastric Cancer Management and Outcomes
- Effects of Radiation Exposure
- Colorectal and Anal Carcinomas
- Esophageal Cancer Research and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Clinical Nutrition and Gastroenterology
- Glioma Diagnosis and Treatment
- Advances in Oncology and Radiotherapy
- Liver Disease and Transplantation
- Radiopharmaceutical Chemistry and Applications
- Enhanced Recovery After Surgery
- Tannin, Tannase and Anticancer Activities
- Oral health in cancer treatment
Sun Yat-sen University
2015-2024
Sun Yat-sen University Cancer Center
2015-2024
Gansu Provincial Hospital
2023
Beijing Institute of Petrochemical Technology
2023
Gansu University of Traditional Chinese Medicine
2023
Zhuhai People's Hospital
2023
The Seventh Affiliated Hospital of Sun Yat-sen University
2019-2022
State Key Laboratory of Oncology in South China
2012-2022
Key Laboratory of Guangdong Province
2022
Southern Medical University
2009-2017
Ultrahigh dose-rate irradiation (FLASH-IR) was reported to be efficient in tumor control while reducing normal tissue radiotoxicity. However, the mechanism of such phenomenon is still unclear. Besides, FLASH experiments using high energy X-ray, most common modality clinical radiotherapy, are rarely reported. This study aims investigate radiobiological response 6 MV X-ray FLASH-IR or conventional IR (CONV-IR).The superconducting linac Chengdu THz Free Electron Laser (CTFEL) facility used for...
Abstract Purpose We aimed to perform the commissioning and clinical evaluation of myQA SRS detector array for patient‐specific quality assurance (PSQA) stereotactic radiosurgery (SRS)/ body radiotherapy (SBRT) plans. Methods To SRS, its dose linearity, dose‐rate dependence, angular field‐size dependence were investigated. Ten SBRT plans selected evaluation: 1) Common deviations based on original plan (Plan0), including multileaf collimator (MLC) positioning deviation treatment introduced. 2)...
Introduction To evaluate the prognostic value of gross tumor volume (TV) in patients with locally recurrent, nonmetastatic nasopharyngeal carcinoma. Methods Between 2001 and 2012, 291 consecutive carcinoma underwent salvage IMRT were retrospectively reviewed. The correlations between TV recurrent T classification analyzed. Survival analyses performed. Receiver operating characteristic (ROC) curves calculated to identify cut-off point TV. Akaike information criterion Harrell's concordance...
This study aims to investigate the feasibility of contouring target volume according residual tumor and decreasing dose regression field after induction chemotherapy (IC) in locoregionally advanced nasopharyngeal carcinoma (NPC).From August 2009 2013, patients with stage III-IVB NPC were treated IC concurrent chemoradiotherapy. Gross nasopharynx (GTVnx)-residual gross cervical lymph node (GTVnd)-residual contoured post-IC primary any N+ disease, respectively. The was included CTVnx1/CTVnd1...
This study was aimed to investigate long-term survivals and toxicities of early-stage nasopharyngeal carcinoma (NPC) in endemic area, evaluating the role chemotherapy stage II patients.Totally 187 patients with newly diagnosed NPC restaged American Joint Committee on Cancer/International Union Against Cancer 8th T1-2N0-1M0 were retrospectively recruited. All received intensity-modulated radiotherapy (IMRT)±chemotherapy (CT) from 2001 2010.With 15.7-year median follow-up, 10-year locoregional...
The purpose of this study was to compare the survival and toxicities in cervical esophageal squamous cell carcinoma (CESCC) treated by concurrent chemoradiothrapy with either three-dimensional conformal radiotherapy (3D-CRT) or intensity-modulated (IMRT) techniques.A total 112 consecutive CESCC patients were retrospectively reviewed. 3D-CRT IMRT groups had been analyzed propensity score matching method, sex, age, Karnofsky performance status, induction chemotherapy, tumor stage well matched....
Substantial morbidity and mortality are associated with postcardiac arrest brain injury (PCABI). MicroRNAs(miRNAs) essential regulators of neuronal metabolism processes have been shown to contribute alleviated neurological after cardiac arrest. In this study, we identified miRNAs related the prognosis patients dysfunction cardiopulmonary resuscitation based on data obtained from Gene Expression Omnibus (GEO) database. Then, explored effects miR-483-5p mitochondrial biogenesis,...
The correlation between primary tumor volume and nasopharyngeal carcinoma (NPC) UICC 2002 T classification, N classification distant metastasis after radiation therapy was discussed to provide further evidence for the inclusion of into TNM staging system.Between February 2001 December 2008, 666 patients with NPC treated intensity-modulated (IMRT) were analyzed retrospectively. Primary gross calculated from treatment planning computed tomography scans. Kruskal-Wallis Mann-Whitney tests used...
Objective To investigate the long-term outcome and prognostic factors of patients with nasopharyngeal carcinoma treated intensity-modulated radiation therapy (IMRT). Methods From February 2001 to December 2006, 419 in Cancer Center Sun yatsen University received IMRT. The number stage Ⅰ,Ⅱ,Ⅲ Ⅳ disease was 28, 113, 202 76, respectively. In all, 182 237 radiotherapy alone chemoradiotherapy. prescription doses were as follows:66-70 Gy/25 -30 f GTV_(nx), 60 -64 GTV_(nd), 55 -62 CTV_1, 42 -54...
The two-dimensional phantom dose verification (2D-PDV) using hybrid plan and planar measurement has been widely used for IMRT treatment QA. Due to the lack of information about correlations between results anatomical structure patients, it is inadequate in clinical evaluation. A three-dimensional (3D-ADV) method was this study evaluate IMRT/VMAT delivery nasopharyngeal carcinoma comparison with 2D-PDV analyzed. Twenty (NPC) patients treated were recruited study. 2D ion-chamber array both...
Abstract Background To analysis the clinical outcomes of concurrent chemoradiotherapy (CCRT) alone based on 10-year results for loco-regionally advanced nasopharyngeal carcinoma (LANPC), so as to provide evidence individualized treatment strategy and designing appropriate trial different risk LANPC patients. Methods Consecutive patients with stage III-IVa (AJCC/UICC 8th) were enrolled in this study. All received radical intensity-modulated radiotherapy (IMRT) cisplatin chemotherapy (CDDP)....